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Development of a mucosal vaccine for influenza viruses: preparation for a potential influenza pandemic.
Expert Rev Vaccines. 2007 Apr; 6(2):193-201.ER

Abstract

Highly pathogenic avian H5N1 influenza A virus has caused influenza outbreaks in poultry and migratory birds in Southeast Asia, Africa and Europe, and there is concern that it could cause a new pandemic. This fear of an emerging pandemic of a new influenza strain underscores the urgency of preparing effective vaccines to meet the pandemic. One way to mitigate current concerns is to develop an influenza vaccine that is fully functional against drift influenza viruses. In our current situation, in which we cannot predict which strain will cause a pandemic, cross-protective immunity using potential and novel mucosal vaccines plays a particularly important role in preventing the spread of highly pathogenic influenza virus.

Authors+Show Affiliations

Hasegawa H
Department of Pathology, National Institute of Infectious Diseases, Gakuen, Musashimurayama-shi, Tokyo, Japan. hasegawa@nih.go.jp
Ichinohe T
No affiliation info available
Tamura S
No affiliation info available
Kurata T
No affiliation info available

MeSH

Administration, TopicalAnimalsBirdsCross ReactionsDisease OutbreaksDrug DesignHumansImmunity, InnateImmunity, MucosalInfluenza A Virus, H5N1 SubtypeInfluenza VaccinesInfluenza in BirdsInfluenza, Human

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

17408369

Citation

Hasegawa, Hideki, et al. "Development of a Mucosal Vaccine for Influenza Viruses: Preparation for a Potential Influenza Pandemic." Expert Review of Vaccines, vol. 6, no. 2, 2007, pp. 193-201.
Hasegawa H, Ichinohe T, Tamura S, et al. Development of a mucosal vaccine for influenza viruses: preparation for a potential influenza pandemic. Expert Rev Vaccines. 2007;6(2):193-201.
Hasegawa, H., Ichinohe, T., Tamura, S., & Kurata, T. (2007). Development of a mucosal vaccine for influenza viruses: preparation for a potential influenza pandemic. Expert Review of Vaccines, 6(2), 193-201.
Hasegawa H, et al. Development of a Mucosal Vaccine for Influenza Viruses: Preparation for a Potential Influenza Pandemic. Expert Rev Vaccines. 2007;6(2):193-201. PubMed PMID: 17408369.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Development of a mucosal vaccine for influenza viruses: preparation for a potential influenza pandemic. AU - Hasegawa,Hideki, AU - Ichinohe,Takeshi, AU - Tamura,Shin-ichi, AU - Kurata,Takeshi, PY - 2007/4/6/pubmed PY - 2007/5/4/medline PY - 2007/4/6/entrez SP - 193 EP - 201 JF - Expert review of vaccines JO - Expert Rev Vaccines VL - 6 IS - 2 N2 - Highly pathogenic avian H5N1 influenza A virus has caused influenza outbreaks in poultry and migratory birds in Southeast Asia, Africa and Europe, and there is concern that it could cause a new pandemic. This fear of an emerging pandemic of a new influenza strain underscores the urgency of preparing effective vaccines to meet the pandemic. One way to mitigate current concerns is to develop an influenza vaccine that is fully functional against drift influenza viruses. In our current situation, in which we cannot predict which strain will cause a pandemic, cross-protective immunity using potential and novel mucosal vaccines plays a particularly important role in preventing the spread of highly pathogenic influenza virus. SN - 1744-8395 UR - https://www.unboundmedicine.com/medline/citation/17408369/Development_of_a_mucosal_vaccine_for_influenza_viruses:_preparation_for_a_potential_influenza_pandemic_ DB - PRIME DP - Unbound Medicine ER -