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Pulmonary vaccine delivery.
Expert Rev Vaccines. 2007 Apr; 6(2):213-26.ER

Abstract

This review will discuss developments in the field of pulmonary vaccine delivery. The possibilities of adopting aerosol-generation technology and specific pharmaceutical formulations for the purpose of pulmonary immunization are described. Aerosol-generation systems might offer advantages with respect to vaccine stability and antigenicity. Adjuvants and their inclusion in vaccine-delivery systems are described. Other formulation components, such as surfactants, particulate systems and dispersion of the aerosols are detailed in this paper. The noninvasive, relatively safe and low-cost nature of pulmonary delivery may provide great benefits to the public health vaccination campaign.

Authors+Show Affiliations

Division of Molecular Pharmaceutics, School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. ludm@email.unc.eduNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

17408371

Citation

Lu, Dongmei, and Anthony J. Hickey. "Pulmonary Vaccine Delivery." Expert Review of Vaccines, vol. 6, no. 2, 2007, pp. 213-26.
Lu D, Hickey AJ. Pulmonary vaccine delivery. Expert Rev Vaccines. 2007;6(2):213-26.
Lu, D., & Hickey, A. J. (2007). Pulmonary vaccine delivery. Expert Review of Vaccines, 6(2), 213-26.
Lu D, Hickey AJ. Pulmonary Vaccine Delivery. Expert Rev Vaccines. 2007;6(2):213-26. PubMed PMID: 17408371.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pulmonary vaccine delivery. AU - Lu,Dongmei, AU - Hickey,Anthony J, PY - 2007/4/6/pubmed PY - 2007/5/4/medline PY - 2007/4/6/entrez SP - 213 EP - 26 JF - Expert review of vaccines JO - Expert Rev Vaccines VL - 6 IS - 2 N2 - This review will discuss developments in the field of pulmonary vaccine delivery. The possibilities of adopting aerosol-generation technology and specific pharmaceutical formulations for the purpose of pulmonary immunization are described. Aerosol-generation systems might offer advantages with respect to vaccine stability and antigenicity. Adjuvants and their inclusion in vaccine-delivery systems are described. Other formulation components, such as surfactants, particulate systems and dispersion of the aerosols are detailed in this paper. The noninvasive, relatively safe and low-cost nature of pulmonary delivery may provide great benefits to the public health vaccination campaign. SN - 1744-8395 UR - https://www.unboundmedicine.com/medline/citation/17408371/Pulmonary_vaccine_delivery_ L2 - http://www.tandfonline.com/doi/full/10.1586/14760584.6.2.213 DB - PRIME DP - Unbound Medicine ER -