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Role of aerobic fitness and aging on cerebral white matter integrity.
Ann N Y Acad Sci 2007; 1097:171-4AN

Abstract

Neuroimaging research suggests that cerebral white matter (WM) integrity, as reflected in fractional anisotropy (FA) via diffusion tensor imaging (DTI), is decreased in older adults, especially in the prefrontal regions of the brain. Behavioral investigations of cognitive functioning suggest that some aspects of cognition may be better preserved in older adults who possess higher levels of aerobic fitness. There are only a few studies, however, investigating potential mechanisms for the improvements in aerobic fitness. Our study suggests that greater aerobic fitness may be related to greater WM integrity in select brain regions.

Authors+Show Affiliations

Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, North Carolina, USA. marks@email.unc.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

17413020

Citation

Marks, Bonita L., et al. "Role of Aerobic Fitness and Aging On Cerebral White Matter Integrity." Annals of the New York Academy of Sciences, vol. 1097, 2007, pp. 171-4.
Marks BL, Madden DJ, Bucur B, et al. Role of aerobic fitness and aging on cerebral white matter integrity. Ann N Y Acad Sci. 2007;1097:171-4.
Marks, B. L., Madden, D. J., Bucur, B., Provenzale, J. M., White, L. E., Cabeza, R., & Huettel, S. A. (2007). Role of aerobic fitness and aging on cerebral white matter integrity. Annals of the New York Academy of Sciences, 1097, pp. 171-4.
Marks BL, et al. Role of Aerobic Fitness and Aging On Cerebral White Matter Integrity. Ann N Y Acad Sci. 2007;1097:171-4. PubMed PMID: 17413020.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Role of aerobic fitness and aging on cerebral white matter integrity. AU - Marks,Bonita L, AU - Madden,David J, AU - Bucur,Barbara, AU - Provenzale,James M, AU - White,Leonard E, AU - Cabeza,Roberto, AU - Huettel,Scott A, PY - 2007/4/7/pubmed PY - 2007/4/26/medline PY - 2007/4/7/entrez SP - 171 EP - 4 JF - Annals of the New York Academy of Sciences JO - Ann. N. Y. Acad. Sci. VL - 1097 N2 - Neuroimaging research suggests that cerebral white matter (WM) integrity, as reflected in fractional anisotropy (FA) via diffusion tensor imaging (DTI), is decreased in older adults, especially in the prefrontal regions of the brain. Behavioral investigations of cognitive functioning suggest that some aspects of cognition may be better preserved in older adults who possess higher levels of aerobic fitness. There are only a few studies, however, investigating potential mechanisms for the improvements in aerobic fitness. Our study suggests that greater aerobic fitness may be related to greater WM integrity in select brain regions. SN - 0077-8923 UR - https://www.unboundmedicine.com/medline/citation/17413020/Role_of_aerobic_fitness_and_aging_on_cerebral_white_matter_integrity_ L2 - https://doi.org/10.1196/annals.1379.022 DB - PRIME DP - Unbound Medicine ER -