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The utility of capsule endoscopy in the diagnosis of Crohn's disease based on patient's symptoms.
J Clin Gastroenterol. 2007 Apr; 41(4):384-7.JC

Abstract

BACKGROUND AND GOALS

Video capsule endoscopy (VCE) enables visualization of the entire small bowel and can identify lesions that may go undetected by conventional endoscopy and radiography. In this study, we assessed whether patient's selection based on symptoms may increase the yield of VCE in the diagnosis of Crohn's disease (CD).

STUDY

Findings of 125 consecutive patients referred for VCE in whom CD may be suspected, were analyzed. Indications for VCE included iron-deficiency anemia, abdominal pain, diarrhea, or a combination of symptoms. Capsule endoscopy (CE) results were defined positive if 4 or more obvious clear ulcers, erosions, or a region with clear exudate and mucosal hyperemia and edema were identified.

RESULTS

One hundred twelve patients were included in the final analysis. Mean age of patients was 44+/-22 years and median follow-up 36+/-15 months. Findings on CE were considered compatible with a diagnosis of CD in 7 patients (6%). In general, CE yielded a diagnosis of CD in a very small portion of the patients (0% to 4%), except in patients undergoing the test for a combination of abdominal pain and diarrhea. In this group, findings suggestive of inflammatory bowel disease were encountered in one-third of the patients (P=0.002).

CONCLUSIONS

The greatest yield of CE in diagnosing CD is achieved in young patients who present with symptoms of abdominal pain plus diarrhea.

Authors+Show Affiliations

Department of Gastroenterology, Sackler School of Medicine, Chaim Sheba Medical Center, Tel Aviv University, Israel.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Evaluation Study
Journal Article

Language

eng

PubMed ID

17413607

Citation

Fidder, Herma H., et al. "The Utility of Capsule Endoscopy in the Diagnosis of Crohn's Disease Based On Patient's Symptoms." Journal of Clinical Gastroenterology, vol. 41, no. 4, 2007, pp. 384-7.
Fidder HH, Nadler M, Lahat A, et al. The utility of capsule endoscopy in the diagnosis of Crohn's disease based on patient's symptoms. J Clin Gastroenterol. 2007;41(4):384-7.
Fidder, H. H., Nadler, M., Lahat, A., Lahav, M., Bardan, E., Avidan, B., & Bar-Meir, S. (2007). The utility of capsule endoscopy in the diagnosis of Crohn's disease based on patient's symptoms. Journal of Clinical Gastroenterology, 41(4), 384-7.
Fidder HH, et al. The Utility of Capsule Endoscopy in the Diagnosis of Crohn's Disease Based On Patient's Symptoms. J Clin Gastroenterol. 2007;41(4):384-7. PubMed PMID: 17413607.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The utility of capsule endoscopy in the diagnosis of Crohn's disease based on patient's symptoms. AU - Fidder,Herma H, AU - Nadler,Moshe, AU - Lahat,Adi, AU - Lahav,Maor, AU - Bardan,Eitan, AU - Avidan,Benjamin, AU - Bar-Meir,Simon, PY - 2007/4/7/pubmed PY - 2007/6/28/medline PY - 2007/4/7/entrez SP - 384 EP - 7 JF - Journal of clinical gastroenterology JO - J Clin Gastroenterol VL - 41 IS - 4 N2 - BACKGROUND AND GOALS: Video capsule endoscopy (VCE) enables visualization of the entire small bowel and can identify lesions that may go undetected by conventional endoscopy and radiography. In this study, we assessed whether patient's selection based on symptoms may increase the yield of VCE in the diagnosis of Crohn's disease (CD). STUDY: Findings of 125 consecutive patients referred for VCE in whom CD may be suspected, were analyzed. Indications for VCE included iron-deficiency anemia, abdominal pain, diarrhea, or a combination of symptoms. Capsule endoscopy (CE) results were defined positive if 4 or more obvious clear ulcers, erosions, or a region with clear exudate and mucosal hyperemia and edema were identified. RESULTS: One hundred twelve patients were included in the final analysis. Mean age of patients was 44+/-22 years and median follow-up 36+/-15 months. Findings on CE were considered compatible with a diagnosis of CD in 7 patients (6%). In general, CE yielded a diagnosis of CD in a very small portion of the patients (0% to 4%), except in patients undergoing the test for a combination of abdominal pain and diarrhea. In this group, findings suggestive of inflammatory bowel disease were encountered in one-third of the patients (P=0.002). CONCLUSIONS: The greatest yield of CE in diagnosing CD is achieved in young patients who present with symptoms of abdominal pain plus diarrhea. SN - 0192-0790 UR - https://www.unboundmedicine.com/medline/citation/17413607/The_utility_of_capsule_endoscopy_in_the_diagnosis_of_Crohn's_disease_based_on_patient's_symptoms_ L2 - https://doi.org/10.1097/01.mcg.0000225621.02094.8a DB - PRIME DP - Unbound Medicine ER -