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Seminal vesicle invasion in radical prostatectomies: which is the most common route of invasion?
Int Urol Nephrol. 2007; 39(4):1097-102.IU

Abstract

INTRODUCTION

Very few studies have been published on seminal vesicle invasion (SVI), and these have obtained conflicting results. The aim of the present investigation was to determine the most frequent of three possible routes of seminal vesicle invasion: (1) extraprostatic extension (EPE) into soft tissue adjacent to the seminal vesicle and then into the wall of the seminal vesicle, (2) invasion via the sheath of the ejaculatory duct, penetrating the muscular wall of the ejaculatory duct or extending up the ejaculatory duct into the seminal vesicle muscle wall, or (3) discontinuous metastases.

MATERIALS AND METHODS

The surgical specimens of 230 consecutive patients submitted to radical prostatectomy were histologically evaluated by complete embedding and whole-mount processing.

RESULTS

Of the surgical specimens obtained from 230 patients, 28 (12.17%) showed the presence of either unilateral or bilateral SVI. The routes of SVI in these 28 specimens were: (1) only via the sheath of the ejaculatory duct (0/28; 0%); (2) discontinuous metastases (3/28; 11%), (3) both EPE and via the sheath of the ejaculatory duct (6/28; 21%), and (4) only EPE (19/28; 68%). One-half (14/28; 50%) of the 28 seminal vesicles involved had unilateral invasion and, in most of these cases (42.85%), EPE was unilateral and ipsilateral.

CONCLUSION

Our results suggest that the most important and most frequent route of SVI is extraprostatic extension of prostate carcinoma into the soft tissue adjacent to the ipsilateral seminal vesicle and then into the wall of the seminal vesicle.

Authors+Show Affiliations

Anatomic Pathology, School of Medicine, State University of Campinas, Caixa Postal 6111, Campinas, 13084-971, Brazil. athanase@fcm.unicamp.brNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17431809

Citation

Billis, Athanase, et al. "Seminal Vesicle Invasion in Radical Prostatectomies: Which Is the Most Common Route of Invasion?" International Urology and Nephrology, vol. 39, no. 4, 2007, pp. 1097-102.
Billis A, Teixeira DA, Stelini RF, et al. Seminal vesicle invasion in radical prostatectomies: which is the most common route of invasion? Int Urol Nephrol. 2007;39(4):1097-102.
Billis, A., Teixeira, D. A., Stelini, R. F., Quintal, M. M., Guimarães, M. S., & Ferreira, U. (2007). Seminal vesicle invasion in radical prostatectomies: which is the most common route of invasion? International Urology and Nephrology, 39(4), 1097-102.
Billis A, et al. Seminal Vesicle Invasion in Radical Prostatectomies: Which Is the Most Common Route of Invasion. Int Urol Nephrol. 2007;39(4):1097-102. PubMed PMID: 17431809.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Seminal vesicle invasion in radical prostatectomies: which is the most common route of invasion? AU - Billis,Athanase, AU - Teixeira,Daniel A, AU - Stelini,Rafael F, AU - Quintal,Maísa M, AU - Guimarães,Marbele S, AU - Ferreira,Ubirajara, Y1 - 2007/03/13/ PY - 2006/12/11/received PY - 2007/01/22/accepted PY - 2007/4/14/pubmed PY - 2008/3/26/medline PY - 2007/4/14/entrez SP - 1097 EP - 102 JF - International urology and nephrology JO - Int Urol Nephrol VL - 39 IS - 4 N2 - INTRODUCTION: Very few studies have been published on seminal vesicle invasion (SVI), and these have obtained conflicting results. The aim of the present investigation was to determine the most frequent of three possible routes of seminal vesicle invasion: (1) extraprostatic extension (EPE) into soft tissue adjacent to the seminal vesicle and then into the wall of the seminal vesicle, (2) invasion via the sheath of the ejaculatory duct, penetrating the muscular wall of the ejaculatory duct or extending up the ejaculatory duct into the seminal vesicle muscle wall, or (3) discontinuous metastases. MATERIALS AND METHODS: The surgical specimens of 230 consecutive patients submitted to radical prostatectomy were histologically evaluated by complete embedding and whole-mount processing. RESULTS: Of the surgical specimens obtained from 230 patients, 28 (12.17%) showed the presence of either unilateral or bilateral SVI. The routes of SVI in these 28 specimens were: (1) only via the sheath of the ejaculatory duct (0/28; 0%); (2) discontinuous metastases (3/28; 11%), (3) both EPE and via the sheath of the ejaculatory duct (6/28; 21%), and (4) only EPE (19/28; 68%). One-half (14/28; 50%) of the 28 seminal vesicles involved had unilateral invasion and, in most of these cases (42.85%), EPE was unilateral and ipsilateral. CONCLUSION: Our results suggest that the most important and most frequent route of SVI is extraprostatic extension of prostate carcinoma into the soft tissue adjacent to the ipsilateral seminal vesicle and then into the wall of the seminal vesicle. SN - 0301-1623 UR - https://www.unboundmedicine.com/medline/citation/17431809/Seminal_vesicle_invasion_in_radical_prostatectomies:_which_is_the_most_common_route_of_invasion L2 - https://doi.org/10.1007/s11255-007-9189-7 DB - PRIME DP - Unbound Medicine ER -