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Cardiovascular effects of anesthesia in ECT: a randomized, double-blind comparison of etomidate, propofol, and thiopental.
J ECT. 2007 Mar; 23(1):6-8.JE

Abstract

Cardiovascular alterations during electroconvulsive therapy (ECT) are a major concern for this treatment. Although several studies have been performed to compare the effects of anesthetics on these alterations, the results are mixed and doubt still exists regarding the choice of the best drug. We conducted a randomized, double-blind clinical trial to compare the effects of 3 anesthetics used in ECT: etomidate, propofol, and thiopental. Patients (N=30) were randomized to receive one of these drugs as the anesthetic for the ECT procedure. Cardiovascular evaluation consisted of the measurement of blood systolic and diastolic pressure and heart rate before and immediately after the end of the seizure for each patient during a course of ECT. The results showed that etomidate, propofol, and thiopental were associated with similar cardiovascular effects.

Authors+Show Affiliations

Clinical Hospital, Institute of Psychiatry, University of Sao Paulo, Brazil. moarosa@hcnet.usp.brNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

17435563

Citation

Rosa, Moacyr Alexandro, et al. "Cardiovascular Effects of Anesthesia in ECT: a Randomized, Double-blind Comparison of Etomidate, Propofol, and Thiopental." The Journal of ECT, vol. 23, no. 1, 2007, pp. 6-8.
Rosa MA, Rosa MO, Marcolin MA, et al. Cardiovascular effects of anesthesia in ECT: a randomized, double-blind comparison of etomidate, propofol, and thiopental. J ECT. 2007;23(1):6-8.
Rosa, M. A., Rosa, M. O., Marcolin, M. A., & Fregni, F. (2007). Cardiovascular effects of anesthesia in ECT: a randomized, double-blind comparison of etomidate, propofol, and thiopental. The Journal of ECT, 23(1), 6-8.
Rosa MA, et al. Cardiovascular Effects of Anesthesia in ECT: a Randomized, Double-blind Comparison of Etomidate, Propofol, and Thiopental. J ECT. 2007;23(1):6-8. PubMed PMID: 17435563.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cardiovascular effects of anesthesia in ECT: a randomized, double-blind comparison of etomidate, propofol, and thiopental. AU - Rosa,Moacyr Alexandro, AU - Rosa,Marina O, AU - Marcolin,Marco A, AU - Fregni,Felipe, PY - 2007/4/17/pubmed PY - 2007/5/16/medline PY - 2007/4/17/entrez SP - 6 EP - 8 JF - The journal of ECT JO - J ECT VL - 23 IS - 1 N2 - Cardiovascular alterations during electroconvulsive therapy (ECT) are a major concern for this treatment. Although several studies have been performed to compare the effects of anesthetics on these alterations, the results are mixed and doubt still exists regarding the choice of the best drug. We conducted a randomized, double-blind clinical trial to compare the effects of 3 anesthetics used in ECT: etomidate, propofol, and thiopental. Patients (N=30) were randomized to receive one of these drugs as the anesthetic for the ECT procedure. Cardiovascular evaluation consisted of the measurement of blood systolic and diastolic pressure and heart rate before and immediately after the end of the seizure for each patient during a course of ECT. The results showed that etomidate, propofol, and thiopental were associated with similar cardiovascular effects. SN - 1095-0680 UR - https://www.unboundmedicine.com/medline/citation/17435563/Cardiovascular_effects_of_anesthesia_in_ECT:_a_randomized_double_blind_comparison_of_etomidate_propofol_and_thiopental_ L2 - https://doi.org/10.1097/01.yct.0000263251.68302.f2 DB - PRIME DP - Unbound Medicine ER -