Tags

Type your tag names separated by a space and hit enter

The effects of soy milk and isoflavone supplements on cognitive performance in healthy, postmenopausal women.
J Nutr Health Aging 2007 Mar-Apr; 11(2):155-64JN

Abstract

RATIONALE

The decline in estrogen concentrations in women after menopause can contribute to health related changes including impairments in cognition, especially memory. Because of the health concerns related to hormone replacement therapy (HRT), alternative approaches to treat menopausal symptoms, such as nutritional supplements and/or diet containing isoflavones, are of interest.

OBJECTIVES

This study investigated whether soy isoflavones (soy milk and supplement) could improve cognitive functioning in healthy, postmenopausal women. PARTICIPANTS, INTERVENTION AND DESIGN: A total of 79 postmenopausal women, 48-65 years of age, completed a double-blind, placebo-controlled trial in which they were randomly assigned to one of three experimental groups: cow's milk and a placebo supplement (control); soy milk and placebo supplement (soy milk, 72 mg isoflavones/day); or cow's milk and isoflavone supplement (isoflavone supplement, 70 mg isoflavones/day).

MEASUREMENTS

Cognitive functioning was assessed using various cognitive tasks before the intervention (baseline) and after the intervention (test).

RESULTS

In contrast to predictions, soy isoflavones did not improve selective attention (Stroop task), visual long-term memory (pattern recognition), short-term visuospatial memory (Benton Visual Retention Test), or visuo-spatial working memory (color match task). Also, the soy milk group showed a decline in verbal working memory (Digit Ordering Task) compared to the soy supplement and control groups.

CONCLUSION

Soy isoflavones consumed as a food or supplement over a 16-week period did not improve or appreciably affect cognitive functioning in healthy, postmenopausal women.

Authors+Show Affiliations

Department of Psychology, Washington State University, Pullman, WA 99164-4820, USA. Fournier@wsunix.wsu.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17435957

Citation

Fournier, L R., et al. "The Effects of Soy Milk and Isoflavone Supplements On Cognitive Performance in Healthy, Postmenopausal Women." The Journal of Nutrition, Health & Aging, vol. 11, no. 2, 2007, pp. 155-64.
Fournier LR, Ryan Borchers TA, Robison LM, et al. The effects of soy milk and isoflavone supplements on cognitive performance in healthy, postmenopausal women. J Nutr Health Aging. 2007;11(2):155-64.
Fournier, L. R., Ryan Borchers, T. A., Robison, L. M., Wiediger, M., Park, J. S., Chew, B. P., ... Beerman, K. A. (2007). The effects of soy milk and isoflavone supplements on cognitive performance in healthy, postmenopausal women. The Journal of Nutrition, Health & Aging, 11(2), pp. 155-64.
Fournier LR, et al. The Effects of Soy Milk and Isoflavone Supplements On Cognitive Performance in Healthy, Postmenopausal Women. J Nutr Health Aging. 2007;11(2):155-64. PubMed PMID: 17435957.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The effects of soy milk and isoflavone supplements on cognitive performance in healthy, postmenopausal women. AU - Fournier,L R, AU - Ryan Borchers,T A, AU - Robison,L M, AU - Wiediger,M, AU - Park,J S, AU - Chew,B P, AU - McGuire,M K, AU - Sclar,D A, AU - Skaer,T L, AU - Beerman,K A, PY - 2007/4/17/pubmed PY - 2007/7/4/medline PY - 2007/4/17/entrez SP - 155 EP - 64 JF - The journal of nutrition, health & aging JO - J Nutr Health Aging VL - 11 IS - 2 N2 - RATIONALE: The decline in estrogen concentrations in women after menopause can contribute to health related changes including impairments in cognition, especially memory. Because of the health concerns related to hormone replacement therapy (HRT), alternative approaches to treat menopausal symptoms, such as nutritional supplements and/or diet containing isoflavones, are of interest. OBJECTIVES: This study investigated whether soy isoflavones (soy milk and supplement) could improve cognitive functioning in healthy, postmenopausal women. PARTICIPANTS, INTERVENTION AND DESIGN: A total of 79 postmenopausal women, 48-65 years of age, completed a double-blind, placebo-controlled trial in which they were randomly assigned to one of three experimental groups: cow's milk and a placebo supplement (control); soy milk and placebo supplement (soy milk, 72 mg isoflavones/day); or cow's milk and isoflavone supplement (isoflavone supplement, 70 mg isoflavones/day). MEASUREMENTS: Cognitive functioning was assessed using various cognitive tasks before the intervention (baseline) and after the intervention (test). RESULTS: In contrast to predictions, soy isoflavones did not improve selective attention (Stroop task), visual long-term memory (pattern recognition), short-term visuospatial memory (Benton Visual Retention Test), or visuo-spatial working memory (color match task). Also, the soy milk group showed a decline in verbal working memory (Digit Ordering Task) compared to the soy supplement and control groups. CONCLUSION: Soy isoflavones consumed as a food or supplement over a 16-week period did not improve or appreciably affect cognitive functioning in healthy, postmenopausal women. SN - 1279-7707 UR - https://www.unboundmedicine.com/medline/citation/17435957/The_effects_of_soy_milk_and_isoflavone_supplements_on_cognitive_performance_in_healthy_postmenopausal_women_ L2 - https://medlineplus.gov/olderadulthealth.html DB - PRIME DP - Unbound Medicine ER -