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Comparison between omega-3 and omega-6 polyunsaturated fatty acid intakes as assessed by a food frequency questionnaire and erythrocyte membrane fatty acid composition in young children.
Eur J Clin Nutr. 2008 Jun; 62(6):733-8.EJ

Abstract

OBJECTIVE

We conducted a dietary validation study in youth aged 1-11 years by comparing dietary intake of omega-3 and omega-6 polyunsaturated fatty acids (PUFAs) as assessed by a parent-completed semiquantitative food frequency questionnaire (FFQ) over time to erythrocyte membrane composition of the same fatty acids.

DESIGN

The study population included youth aged 1-11 years who were participants in the Diabetes Autoimmunity Study in the Young (DAISY), a longitudinal study in Denver, Colorado that is following a cohort of youth at risk for developing type I diabetes. Four hundred and four children who had erythrocyte membrane fatty acid data matched to an FFQ corresponding to the same time frame for a total of 917 visits (matches) were included. PUFA intake was expressed both as g/day (adjusted for total energy) and as percent of total fat intake. We used mixed models to test the association and calculate the correlation between the erythrocyte membrane estimates and PUFA intake using all records of data for each youth.

RESULTS

Intakes of total omega-3 fatty acids (beta=0.52, P<0.0001, rho=0.23) and marine PUFAs (beta=1.62, P<0.0001, rho=0.42), as a percent of total fat in the diet, were associated with percent of omega-3 and marine PUFAs in the erythrocyte membrane. Intakes of omega-6 PUFAs (beta=0.04, P=0.418, rho=0.05) and arachidonic acid (beta=0.31, P=0.774, rho=0.01) were not associated.

CONCLUSIONS

In these young children, an FFQ using parental report provided estimates of average long-term intakes of marine PUFAs that correlated well with their erythrocyte cell membrane fatty acid status.

Authors+Show Affiliations

Department of Preventive Medicine and Biometrics, University of Colorado at Denver and Health Sciences Center, Denver, CO 80262, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Validation Study

Language

eng

PubMed ID

17440518

Citation

Orton, H D., et al. "Comparison Between Omega-3 and Omega-6 Polyunsaturated Fatty Acid Intakes as Assessed By a Food Frequency Questionnaire and Erythrocyte Membrane Fatty Acid Composition in Young Children." European Journal of Clinical Nutrition, vol. 62, no. 6, 2008, pp. 733-8.
Orton HD, Szabo NJ, Clare-Salzler M, et al. Comparison between omega-3 and omega-6 polyunsaturated fatty acid intakes as assessed by a food frequency questionnaire and erythrocyte membrane fatty acid composition in young children. Eur J Clin Nutr. 2008;62(6):733-8.
Orton, H. D., Szabo, N. J., Clare-Salzler, M., & Norris, J. M. (2008). Comparison between omega-3 and omega-6 polyunsaturated fatty acid intakes as assessed by a food frequency questionnaire and erythrocyte membrane fatty acid composition in young children. European Journal of Clinical Nutrition, 62(6), 733-8.
Orton HD, et al. Comparison Between Omega-3 and Omega-6 Polyunsaturated Fatty Acid Intakes as Assessed By a Food Frequency Questionnaire and Erythrocyte Membrane Fatty Acid Composition in Young Children. Eur J Clin Nutr. 2008;62(6):733-8. PubMed PMID: 17440518.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison between omega-3 and omega-6 polyunsaturated fatty acid intakes as assessed by a food frequency questionnaire and erythrocyte membrane fatty acid composition in young children. AU - Orton,H D, AU - Szabo,N J, AU - Clare-Salzler,M, AU - Norris,J M, Y1 - 2007/04/18/ PY - 2007/4/19/pubmed PY - 2008/10/24/medline PY - 2007/4/19/entrez SP - 733 EP - 8 JF - European journal of clinical nutrition JO - Eur J Clin Nutr VL - 62 IS - 6 N2 - OBJECTIVE: We conducted a dietary validation study in youth aged 1-11 years by comparing dietary intake of omega-3 and omega-6 polyunsaturated fatty acids (PUFAs) as assessed by a parent-completed semiquantitative food frequency questionnaire (FFQ) over time to erythrocyte membrane composition of the same fatty acids. DESIGN: The study population included youth aged 1-11 years who were participants in the Diabetes Autoimmunity Study in the Young (DAISY), a longitudinal study in Denver, Colorado that is following a cohort of youth at risk for developing type I diabetes. Four hundred and four children who had erythrocyte membrane fatty acid data matched to an FFQ corresponding to the same time frame for a total of 917 visits (matches) were included. PUFA intake was expressed both as g/day (adjusted for total energy) and as percent of total fat intake. We used mixed models to test the association and calculate the correlation between the erythrocyte membrane estimates and PUFA intake using all records of data for each youth. RESULTS: Intakes of total omega-3 fatty acids (beta=0.52, P<0.0001, rho=0.23) and marine PUFAs (beta=1.62, P<0.0001, rho=0.42), as a percent of total fat in the diet, were associated with percent of omega-3 and marine PUFAs in the erythrocyte membrane. Intakes of omega-6 PUFAs (beta=0.04, P=0.418, rho=0.05) and arachidonic acid (beta=0.31, P=0.774, rho=0.01) were not associated. CONCLUSIONS: In these young children, an FFQ using parental report provided estimates of average long-term intakes of marine PUFAs that correlated well with their erythrocyte cell membrane fatty acid status. SN - 0954-3007 UR - https://www.unboundmedicine.com/medline/citation/17440518/Comparison_between_omega_3_and_omega_6_polyunsaturated_fatty_acid_intakes_as_assessed_by_a_food_frequency_questionnaire_and_erythrocyte_membrane_fatty_acid_composition_in_young_children_ L2 - http://dx.doi.org/10.1038/sj.ejcn.1602763 DB - PRIME DP - Unbound Medicine ER -