Tags

Type your tag names separated by a space and hit enter

Pakistani immigrant children and adults in Denmark have severely low vitamin D status.

Abstract

OBJECTIVE

To determine vitamin D and bone status in adolescent girls, pre-menopausal women and men of Pakistani origin, to single out determinants of vitamin D status and to determine the association between vitamin D status, bone metabolism and bone status.

SUBJECTS/METHODS

Cross-sectional study, Copenhagen (55 degrees N), January-November. Serum 25-hydroxyvitamin D (S-25OHD), serum intact parathyroid hormone (S-iPTH), bone turnover markers and whole body and lumbar spine bone mineral density were measured. Sun, smoking and clothing habits, age, body mass index (BMI), and vitamin D and calcium from food and from supplements were recorded. Thirty-seven girls (median age, range: 12.2 years, 10.1-14.7), 115 women (36.2 years, 18.1-52.7) and 95 men (38.3 years, 17.9-63.5) of Pakistani origin (immigrants or descendants with Pakistani parents) took part in the study.

RESULTS

Median concentration of S-25OHD was 10.9, 12.0 and 20.7 nmol/l for girls, women and men, respectively. Forty-seven per cent of the girls, 37% of the women and 24% of the men had elevated S-iPTH, and there was a negative relationship between S-iPTH and S-25OHD. Use of vitamin D-containing supplements had a positive association with S-25OHD for men (P=0.04) and women (P=0.0008). Twenty-one per cent of the women and 34% of the men had osteopenia. Neither S-25OHD nor S-iPTH was associated with lumbar spine or whole body bone mineral content.

CONCLUSIONS

Severely low vitamin D status and elevated S-iPTH is common among Pakistani immigrants in Denmark. The low vitamin D status is not associated with bone markers or bone mass among relatively young Pakistanis.

Links

  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Department of Nutrition, National Food Institute, Technical University of Denmark, Mørkhøj Bygade 19, Søborg, Denmark. ria@food.dtu.dk

    , , , , , ,

    Source

    MeSH

    Adolescent
    Adult
    Bone Density
    Bone Density Conservation Agents
    Bone and Bones
    Calcium, Dietary
    Child
    Cross-Sectional Studies
    Denmark
    Dietary Supplements
    Female
    Humans
    Male
    Middle Aged
    Nutritional Status
    Pakistan
    Parathyroid Hormone
    Skin Pigmentation
    Smoking
    Sunlight
    Vitamin D
    Vitamin D Deficiency

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    17440527

    Citation

    Andersen, R, et al. "Pakistani Immigrant Children and Adults in Denmark Have Severely Low Vitamin D Status." European Journal of Clinical Nutrition, vol. 62, no. 5, 2008, pp. 625-34.
    Andersen R, Mølgaard C, Skovgaard LT, et al. Pakistani immigrant children and adults in Denmark have severely low vitamin D status. Eur J Clin Nutr. 2008;62(5):625-34.
    Andersen, R., Mølgaard, C., Skovgaard, L. T., Brot, C., Cashman, K. D., Jakobsen, J., ... Ovesen, L. (2008). Pakistani immigrant children and adults in Denmark have severely low vitamin D status. European Journal of Clinical Nutrition, 62(5), pp. 625-34.
    Andersen R, et al. Pakistani Immigrant Children and Adults in Denmark Have Severely Low Vitamin D Status. Eur J Clin Nutr. 2008;62(5):625-34. PubMed PMID: 17440527.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Pakistani immigrant children and adults in Denmark have severely low vitamin D status. AU - Andersen,R, AU - Mølgaard,C, AU - Skovgaard,L T, AU - Brot,C, AU - Cashman,K D, AU - Jakobsen,J, AU - Lamberg-Allardt,C, AU - Ovesen,L, Y1 - 2007/04/18/ PY - 2007/4/19/pubmed PY - 2008/9/16/medline PY - 2007/4/19/entrez SP - 625 EP - 34 JF - European journal of clinical nutrition JO - Eur J Clin Nutr VL - 62 IS - 5 N2 - OBJECTIVE: To determine vitamin D and bone status in adolescent girls, pre-menopausal women and men of Pakistani origin, to single out determinants of vitamin D status and to determine the association between vitamin D status, bone metabolism and bone status. SUBJECTS/METHODS: Cross-sectional study, Copenhagen (55 degrees N), January-November. Serum 25-hydroxyvitamin D (S-25OHD), serum intact parathyroid hormone (S-iPTH), bone turnover markers and whole body and lumbar spine bone mineral density were measured. Sun, smoking and clothing habits, age, body mass index (BMI), and vitamin D and calcium from food and from supplements were recorded. Thirty-seven girls (median age, range: 12.2 years, 10.1-14.7), 115 women (36.2 years, 18.1-52.7) and 95 men (38.3 years, 17.9-63.5) of Pakistani origin (immigrants or descendants with Pakistani parents) took part in the study. RESULTS: Median concentration of S-25OHD was 10.9, 12.0 and 20.7 nmol/l for girls, women and men, respectively. Forty-seven per cent of the girls, 37% of the women and 24% of the men had elevated S-iPTH, and there was a negative relationship between S-iPTH and S-25OHD. Use of vitamin D-containing supplements had a positive association with S-25OHD for men (P=0.04) and women (P=0.0008). Twenty-one per cent of the women and 34% of the men had osteopenia. Neither S-25OHD nor S-iPTH was associated with lumbar spine or whole body bone mineral content. CONCLUSIONS: Severely low vitamin D status and elevated S-iPTH is common among Pakistani immigrants in Denmark. The low vitamin D status is not associated with bone markers or bone mass among relatively young Pakistanis. SN - 0954-3007 UR - https://www.unboundmedicine.com/medline/citation/17440527/Pakistani_immigrant_children_and_adults_in_Denmark_have_severely_low_vitamin_D_status_ L2 - http://dx.doi.org/10.1038/sj.ejcn.1602753 DB - PRIME DP - Unbound Medicine ER -