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GliSODin, a vegetal sod with gliadin, as preventative agent vs. atherosclerosis, as confirmed with carotid ultrasound-B imaging.

Abstract

Prevention of cardiovascular disease should target high-risk subjects based on genetic/familial factors, blood chemistry, blood pressure, body mass index (BMI), and a history of/or current cigarette smoking. We selected active adults (n=76) aged 30-60 and investigated these risk factors, in order to recommend preventive measures. Another interesting variable is the preclinical status or atheroma of the arterial (carotid) wall or lumen. We also investigated the presence of oxidative stress in, and the anti-oxidant status of these subjects. We studied the anti-oxidative efficacy of superoxide dismutase (SOD) and variations of malondialdehyde (MDA). Supplementation with GliSODin, a vegetal SOD associated with gliadin, was effective in controlling the thickness of the carotid artery intima and media layers as measured by ultrasonography-B. We could demonstrate the preventive efficacy of GliSODin at a preclinical stage in subjects with risk factors of cardiovascular disease.

Authors+Show Affiliations

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Association Nationale de Prevention Médicale, 14, rue de l'Abbé Grégoire, F-75005 Paris.

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Source

MeSH

Adult
Carotid Arteries
Carotid Artery Diseases
Dietary Supplements
Female
Gliadin
Humans
Male
Malondialdehyde
Middle Aged
Superoxide Dismutase
Ultrasonography

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17441415

Citation

Cloarec, M, et al. "GliSODin, a Vegetal Sod With Gliadin, as Preventative Agent Vs. Atherosclerosis, as Confirmed With Carotid ultrasound-B Imaging." European Annals of Allergy and Clinical Immunology, vol. 39, no. 2, 2007, pp. 45-50.
Cloarec M, Caillard P, Provost JC, et al. GliSODin, a vegetal sod with gliadin, as preventative agent vs. atherosclerosis, as confirmed with carotid ultrasound-B imaging. Eur Ann Allergy Clin Immunol. 2007;39(2):45-50.
Cloarec, M., Caillard, P., Provost, J. C., Dever, J. M., Elbeze, Y., & Zamaria, N. (2007). GliSODin, a vegetal sod with gliadin, as preventative agent vs. atherosclerosis, as confirmed with carotid ultrasound-B imaging. European Annals of Allergy and Clinical Immunology, 39(2), pp. 45-50.
Cloarec M, et al. GliSODin, a Vegetal Sod With Gliadin, as Preventative Agent Vs. Atherosclerosis, as Confirmed With Carotid ultrasound-B Imaging. Eur Ann Allergy Clin Immunol. 2007;39(2):45-50. PubMed PMID: 17441415.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - GliSODin, a vegetal sod with gliadin, as preventative agent vs. atherosclerosis, as confirmed with carotid ultrasound-B imaging. AU - Cloarec,M, AU - Caillard,P, AU - Provost,J C, AU - Dever,J M, AU - Elbeze,Y, AU - Zamaria,N, PY - 2007/4/20/pubmed PY - 2007/5/9/medline PY - 2007/4/20/entrez SP - 45 EP - 50 JF - European annals of allergy and clinical immunology JO - Eur Ann Allergy Clin Immunol VL - 39 IS - 2 N2 - Prevention of cardiovascular disease should target high-risk subjects based on genetic/familial factors, blood chemistry, blood pressure, body mass index (BMI), and a history of/or current cigarette smoking. We selected active adults (n=76) aged 30-60 and investigated these risk factors, in order to recommend preventive measures. Another interesting variable is the preclinical status or atheroma of the arterial (carotid) wall or lumen. We also investigated the presence of oxidative stress in, and the anti-oxidant status of these subjects. We studied the anti-oxidative efficacy of superoxide dismutase (SOD) and variations of malondialdehyde (MDA). Supplementation with GliSODin, a vegetal SOD associated with gliadin, was effective in controlling the thickness of the carotid artery intima and media layers as measured by ultrasonography-B. We could demonstrate the preventive efficacy of GliSODin at a preclinical stage in subjects with risk factors of cardiovascular disease. SN - 1764-1489 UR - https://www.unboundmedicine.com/medline/citation/17441415/abstract/GliSODin_a_vegetal_sod_with_gliadin_as_preventative_agent_vs_atherosclerosis_as_confirmed_with_carotid_ultrasound_B_imaging L2 - https://ClinicalTrials.gov/search/term=17441415 [PUBMED-IDS] DB - PRIME DP - Unbound Medicine ER -