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Survey of prick test, total and specific age during food allergy in children.
Eur Ann Allergy Clin Immunol. 2007 Feb; 39(2):51-7.EA

Abstract

AIM

To analyze the results of a systematic survey of biological tests in a symptomatic pediatric population consulting for the exploration of a possible food allergy.

PATIENTS AND METHODS

406 children included in this study, mean age 3.3+3.2 years (2 months-16 years), 159 girls and 247 boys, had cutaneous tests (Stallergènes, Paris, France), assaying of total and specific IgE, and RAST Fx5 (Pharmacia & Upjohn Diagnostics AB, Uppsala, Sweden). Those children suffering from eczema (34.9%), digestive disorders (26.1%), ORL and pulmonary (8.3%), anaphylactic choc (3.4%) or mixed symptoms (27.3%).

RESULTS

The overall positivity of cutaneous tests, all confused age periods, was 34.1% with the following order: egg white (52%, p < 0.05 vs. other food), peanut (46%), egg yolk (42%), fish (34%), wheat (33%), soy (32%), cow's milk (24%) and rice (17%). It decreased significantly with age only for the egg white, 61% (0-1 year) and 68% (1-2 years) vs 31% (> 6 years), p < 0.05. The positivity of cutaneous tests for egg and peanut was more frequent with eczema than with digestive manifestations (64% vs. 44%, 57.6% vs. 34% and 56% vs. 38.7%, p < 0.05). The title of total IgE increased with age, r 0.5 p 0.001. The positivity of specific food IgE was more frequent at 4-6 years (68%) than at 0-1 year (36%), p < 0.05. It revealed, all confused age periods, the following order: egg white (74%) and peanut (64%), p < 0.05 vs. other food, cow's milk (59%), wheat (55%), soy (45%) and fish (24%). The number of high specific food IgE titers was significantly higher than the number of positive cutaneous tests by order of frequency; egg white, peanut, cow's milk, wheat and soy, p < 0.05; the reverse was observed for fish, p < 0.05. Percentage of subjects combining a high title of specific food IgE and a positive cutaneous test for egg white (39.4%) was significantly higher than the percentage of those combining a high RAST Fx5 title and a positive cutaneous test for at least one of 6 corresponding foods (25.2%), p < 0.05.

CONCLUSION

The positivity of different food cutaneous tests, the rate of total and specific IgE titers and the agreement of the results varied according to age, food and symptoms.

Authors+Show Affiliations

Department of Pediatrics-Neonatology, Pediatric Gastroenterology et Nutrition Unit, Hôpital Cochin-Saint Vincent de Paul, 82, avenue Denfert Rochereau, 75674 Paris, France.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17441416

Citation

Kalach, N, et al. "Survey of Prick Test, Total and Specific Age During Food Allergy in Children." European Annals of Allergy and Clinical Immunology, vol. 39, no. 2, 2007, pp. 51-7.
Kalach N, Soulaines P, Imad AS, et al. Survey of prick test, total and specific age during food allergy in children. Eur Ann Allergy Clin Immunol. 2007;39(2):51-7.
Kalach, N., Soulaines, P., Imad, A. S., Salloum, A., Guerin, S., de Boissieu, D., & Dupont, C. (2007). Survey of prick test, total and specific age during food allergy in children. European Annals of Allergy and Clinical Immunology, 39(2), 51-7.
Kalach N, et al. Survey of Prick Test, Total and Specific Age During Food Allergy in Children. Eur Ann Allergy Clin Immunol. 2007;39(2):51-7. PubMed PMID: 17441416.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Survey of prick test, total and specific age during food allergy in children. AU - Kalach,N, AU - Soulaines,P, AU - Imad,A S, AU - Salloum,A, AU - Guerin,S, AU - de Boissieu,D, AU - Dupont,C, PY - 2007/4/20/pubmed PY - 2007/5/9/medline PY - 2007/4/20/entrez SP - 51 EP - 7 JF - European annals of allergy and clinical immunology JO - Eur Ann Allergy Clin Immunol VL - 39 IS - 2 N2 - AIM: To analyze the results of a systematic survey of biological tests in a symptomatic pediatric population consulting for the exploration of a possible food allergy. PATIENTS AND METHODS: 406 children included in this study, mean age 3.3+3.2 years (2 months-16 years), 159 girls and 247 boys, had cutaneous tests (Stallergènes, Paris, France), assaying of total and specific IgE, and RAST Fx5 (Pharmacia & Upjohn Diagnostics AB, Uppsala, Sweden). Those children suffering from eczema (34.9%), digestive disorders (26.1%), ORL and pulmonary (8.3%), anaphylactic choc (3.4%) or mixed symptoms (27.3%). RESULTS: The overall positivity of cutaneous tests, all confused age periods, was 34.1% with the following order: egg white (52%, p < 0.05 vs. other food), peanut (46%), egg yolk (42%), fish (34%), wheat (33%), soy (32%), cow's milk (24%) and rice (17%). It decreased significantly with age only for the egg white, 61% (0-1 year) and 68% (1-2 years) vs 31% (> 6 years), p < 0.05. The positivity of cutaneous tests for egg and peanut was more frequent with eczema than with digestive manifestations (64% vs. 44%, 57.6% vs. 34% and 56% vs. 38.7%, p < 0.05). The title of total IgE increased with age, r 0.5 p 0.001. The positivity of specific food IgE was more frequent at 4-6 years (68%) than at 0-1 year (36%), p < 0.05. It revealed, all confused age periods, the following order: egg white (74%) and peanut (64%), p < 0.05 vs. other food, cow's milk (59%), wheat (55%), soy (45%) and fish (24%). The number of high specific food IgE titers was significantly higher than the number of positive cutaneous tests by order of frequency; egg white, peanut, cow's milk, wheat and soy, p < 0.05; the reverse was observed for fish, p < 0.05. Percentage of subjects combining a high title of specific food IgE and a positive cutaneous test for egg white (39.4%) was significantly higher than the percentage of those combining a high RAST Fx5 title and a positive cutaneous test for at least one of 6 corresponding foods (25.2%), p < 0.05. CONCLUSION: The positivity of different food cutaneous tests, the rate of total and specific IgE titers and the agreement of the results varied according to age, food and symptoms. SN - 1764-1489 UR - https://www.unboundmedicine.com/medline/citation/17441416/Survey_of_prick_test_total_and_specific_age_during_food_allergy_in_children_ L2 - https://medlineplus.gov/foodallergy.html DB - PRIME DP - Unbound Medicine ER -