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Impaired postexercise cardiovascular autonomic modulation in middle-aged women with type 2 diabetes.
Eur J Cardiovasc Prev Rehabil. 2007 Apr; 14(2):237-43.EJ

Abstract

BACKGROUND

Type 2 diabetes is associated with cardiovascular autonomic dysfunction. Postexercise autonomic modulation may be different in obese individuals with and without type 2 diabetes. We examined postexercise responses in nondiabetic and diabetic women aged 40-60 years.

METHODS

Hemodynamics, high-frequency and low-frequency of RR interval, low-frequency of systolic blood pressure variability and baroreflex sensitivity were evaluated before and after a 20 min walk at approximately 65% of VO2 peak in eight lean, 12 obese without type 2 diabetes and eight women with type 2 diabetes. Postexercise measurements were obtained at 10-15, 20-25 and 30-35 min.

RESULTS

Systolic blood pressure decreased at 10 (P<0.001) and 20 min (P<0.01) in all groups. Total peripheral resistance decreased at 10 min in all women, but the subsequent increase at 20 min was greater (P<0.01) in lean than in diabetic women. Log-transformed low-frequency of systolic blood pressure increased (P<0.01) at 10 and 20 min in all women, but the increase at 10 min was smaller (P<0.05) in diabetic than in lean women. Heart rate was increased (P<0.001) at 10 min in all women and at 20 min in both obese groups. Both log-transformed high-frequency of RR interval and baroreflex sensitivity decreased at 10 and 20 min of recovery in all groups. A group-by-time interaction (P<0.05) was observed for heart rate and baroreflex sensitivity as a lower heart rate and higher baroreflex sensitivity were observed in lean women than in women with type 2 diabetes.

CONCLUSIONS

Reduced postexercise baroreflex sensitivity and responses to autonomic cardiovascular activity contribute to an attenuated recovery of heart rate and total peripheral resistance after brisk walking in middle-aged obese women with type 2 diabetes.

Authors+Show Affiliations

Department of Nutrition, Food and Exercise Sciences, Florida State University, Tallahassee, FL 32306-1493, USA. afiguero@fsu.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

17446802

Citation

Figueroa, Arturo, et al. "Impaired Postexercise Cardiovascular Autonomic Modulation in Middle-aged Women With Type 2 Diabetes." European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups On Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, vol. 14, no. 2, 2007, pp. 237-43.
Figueroa A, Baynard T, Fernhall B, et al. Impaired postexercise cardiovascular autonomic modulation in middle-aged women with type 2 diabetes. Eur J Cardiovasc Prev Rehabil. 2007;14(2):237-43.
Figueroa, A., Baynard, T., Fernhall, B., Carhart, R., & Kanaley, J. A. (2007). Impaired postexercise cardiovascular autonomic modulation in middle-aged women with type 2 diabetes. European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups On Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, 14(2), 237-43.
Figueroa A, et al. Impaired Postexercise Cardiovascular Autonomic Modulation in Middle-aged Women With Type 2 Diabetes. Eur J Cardiovasc Prev Rehabil. 2007;14(2):237-43. PubMed PMID: 17446802.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Impaired postexercise cardiovascular autonomic modulation in middle-aged women with type 2 diabetes. AU - Figueroa,Arturo, AU - Baynard,Tracy, AU - Fernhall,Bo, AU - Carhart,Robert, AU - Kanaley,Jill A, PY - 2007/4/21/pubmed PY - 2007/9/21/medline PY - 2007/4/21/entrez SP - 237 EP - 43 JF - European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology JO - Eur J Cardiovasc Prev Rehabil VL - 14 IS - 2 N2 - BACKGROUND: Type 2 diabetes is associated with cardiovascular autonomic dysfunction. Postexercise autonomic modulation may be different in obese individuals with and without type 2 diabetes. We examined postexercise responses in nondiabetic and diabetic women aged 40-60 years. METHODS: Hemodynamics, high-frequency and low-frequency of RR interval, low-frequency of systolic blood pressure variability and baroreflex sensitivity were evaluated before and after a 20 min walk at approximately 65% of VO2 peak in eight lean, 12 obese without type 2 diabetes and eight women with type 2 diabetes. Postexercise measurements were obtained at 10-15, 20-25 and 30-35 min. RESULTS: Systolic blood pressure decreased at 10 (P<0.001) and 20 min (P<0.01) in all groups. Total peripheral resistance decreased at 10 min in all women, but the subsequent increase at 20 min was greater (P<0.01) in lean than in diabetic women. Log-transformed low-frequency of systolic blood pressure increased (P<0.01) at 10 and 20 min in all women, but the increase at 10 min was smaller (P<0.05) in diabetic than in lean women. Heart rate was increased (P<0.001) at 10 min in all women and at 20 min in both obese groups. Both log-transformed high-frequency of RR interval and baroreflex sensitivity decreased at 10 and 20 min of recovery in all groups. A group-by-time interaction (P<0.05) was observed for heart rate and baroreflex sensitivity as a lower heart rate and higher baroreflex sensitivity were observed in lean women than in women with type 2 diabetes. CONCLUSIONS: Reduced postexercise baroreflex sensitivity and responses to autonomic cardiovascular activity contribute to an attenuated recovery of heart rate and total peripheral resistance after brisk walking in middle-aged obese women with type 2 diabetes. SN - 1741-8267 UR - https://www.unboundmedicine.com/medline/citation/17446802/Impaired_postexercise_cardiovascular_autonomic_modulation_in_middle_aged_women_with_type_2_diabetes_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=linkout&amp;SEARCH=17446802.ui DB - PRIME DP - Unbound Medicine ER -