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An unusual case of reactive lymphocytosis mimicking acute leukemia.
Pediatr Hematol Oncol. 2007 Mar; 24(2):129-35.PH

Abstract

The diagnosis of acute leukemia is based on a combination of clinical, hematological, morphological, cytogenetic, and immunophenotypic data. The authors report a case of reactive lymphocytosis with extremely elevated lymphocytic and lymphoblastic leukocytosis that mimicked acute lymphoblastic leukemia, not only morphologically, but also in immunophenotypic analysis. They could not determine any underlying disease marker other than infectious symptoms that were present for 20 days prior to presentation to their clinic. Although this case presented with extremely high lymphocytic leukocytosis, the patient had normal blood cell lineage, a moderate level of blastic cells in bone marrow, and normal physical findings. These findings convinced the authors to follow up the patient before beginning treatment.

Authors+Show Affiliations

Department of Pediatrics, Division of Pediatric Hematology, Hacettepe University Faculty of Medicine, Sihhiye, Ankara, Turkey.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

17454779

Citation

Yetgin, Sevgi, et al. "An Unusual Case of Reactive Lymphocytosis Mimicking Acute Leukemia." Pediatric Hematology and Oncology, vol. 24, no. 2, 2007, pp. 129-35.
Yetgin S, Kuskonmaz B, Aytaç S, et al. An unusual case of reactive lymphocytosis mimicking acute leukemia. Pediatr Hematol Oncol. 2007;24(2):129-35.
Yetgin, S., Kuskonmaz, B., Aytaç, S., & Tavil, B. (2007). An unusual case of reactive lymphocytosis mimicking acute leukemia. Pediatric Hematology and Oncology, 24(2), 129-35.
Yetgin S, et al. An Unusual Case of Reactive Lymphocytosis Mimicking Acute Leukemia. Pediatr Hematol Oncol. 2007;24(2):129-35. PubMed PMID: 17454779.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - An unusual case of reactive lymphocytosis mimicking acute leukemia. AU - Yetgin,Sevgi, AU - Kuskonmaz,Baris, AU - Aytaç,Selin, AU - Tavil,Betül, PY - 2007/4/25/pubmed PY - 2007/11/6/medline PY - 2007/4/25/entrez SP - 129 EP - 35 JF - Pediatric hematology and oncology JO - Pediatr Hematol Oncol VL - 24 IS - 2 N2 - The diagnosis of acute leukemia is based on a combination of clinical, hematological, morphological, cytogenetic, and immunophenotypic data. The authors report a case of reactive lymphocytosis with extremely elevated lymphocytic and lymphoblastic leukocytosis that mimicked acute lymphoblastic leukemia, not only morphologically, but also in immunophenotypic analysis. They could not determine any underlying disease marker other than infectious symptoms that were present for 20 days prior to presentation to their clinic. Although this case presented with extremely high lymphocytic leukocytosis, the patient had normal blood cell lineage, a moderate level of blastic cells in bone marrow, and normal physical findings. These findings convinced the authors to follow up the patient before beginning treatment. SN - 1521-0669 UR - https://www.unboundmedicine.com/medline/citation/17454779/An_unusual_case_of_reactive_lymphocytosis_mimicking_acute_leukemia_ L2 - https://www.tandfonline.com/doi/full/10.1080/08880010601069948 DB - PRIME DP - Unbound Medicine ER -