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Role of myeloid human cytomegalovirus infection in children's idiopathic thrombocytopenic purpura.
Pediatr Hematol Oncol. 2007 Apr-May; 24(3):179-88.PH

Abstract

This project explores the specificity of myeloid human cytomegalovirus (HCMV) infection in pathogenesis of idiopathic thrombocytopenic purpura (ITP). Eighty-one subjects with ITP were observed. HCMV early antigen and related myeloid cells in bone marrow, and platelet, HCMV IgM, and IgG in blood were tested. The results presented potent evidence that myeloid HCMV infection is a specific factor in children's ITP: patients of ITP with myeloid HCMV infection had a tendency for exacerbation, refractoriness, and chronic advance. However, HCMV did not affect the quantity of megakaryocyte, which showed the complicated relationships between HCMV and ITP.

Authors+Show Affiliations

Department of Gastroenterology and Hepatology, Wuhan Children's Hospital, Wuhan, Hubei Province, People's Republic of China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17454787

Citation

Ding, Yan, et al. "Role of Myeloid Human Cytomegalovirus Infection in Children's Idiopathic Thrombocytopenic Purpura." Pediatric Hematology and Oncology, vol. 24, no. 3, 2007, pp. 179-88.
Ding Y, Zhao L, Mei H, et al. Role of myeloid human cytomegalovirus infection in children's idiopathic thrombocytopenic purpura. Pediatr Hematol Oncol. 2007;24(3):179-88.
Ding, Y., Zhao, L., Mei, H., Zhang, S. L., & Huang, Z. H. (2007). Role of myeloid human cytomegalovirus infection in children's idiopathic thrombocytopenic purpura. Pediatric Hematology and Oncology, 24(3), 179-88.
Ding Y, et al. Role of Myeloid Human Cytomegalovirus Infection in Children's Idiopathic Thrombocytopenic Purpura. Pediatr Hematol Oncol. 2007 Apr-May;24(3):179-88. PubMed PMID: 17454787.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Role of myeloid human cytomegalovirus infection in children's idiopathic thrombocytopenic purpura. AU - Ding,Yan, AU - Zhao,Lei, AU - Mei,Hong, AU - Zhang,Shu-Ling, AU - Huang,Zhi-Hua, PY - 2007/4/25/pubmed PY - 2007/9/28/medline PY - 2007/4/25/entrez SP - 179 EP - 88 JF - Pediatric hematology and oncology JO - Pediatr Hematol Oncol VL - 24 IS - 3 N2 - This project explores the specificity of myeloid human cytomegalovirus (HCMV) infection in pathogenesis of idiopathic thrombocytopenic purpura (ITP). Eighty-one subjects with ITP were observed. HCMV early antigen and related myeloid cells in bone marrow, and platelet, HCMV IgM, and IgG in blood were tested. The results presented potent evidence that myeloid HCMV infection is a specific factor in children's ITP: patients of ITP with myeloid HCMV infection had a tendency for exacerbation, refractoriness, and chronic advance. However, HCMV did not affect the quantity of megakaryocyte, which showed the complicated relationships between HCMV and ITP. SN - 1521-0669 UR - https://www.unboundmedicine.com/medline/citation/17454787/Role_of_myeloid_human_cytomegalovirus_infection_in_children's_idiopathic_thrombocytopenic_purpura_ L2 - https://www.tandfonline.com/doi/full/10.1080/08880010601166421 DB - PRIME DP - Unbound Medicine ER -