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[Migraine and cortical spreading depression].
Agri 2006; 18(4):24-30AGRI

Abstract

Migraine is an episodic headache disorder accompanied by various neurological, gastrointestinal and autonomic changes. In one fifth of the migraineurs, a neurological disturbance (visual, sensory or motor) appears during or before the development of the headache called migraine aura. Cortical spreading depression (CSD) is a transient neuronal depolarization that spreads across unilateral hemisphere from a focus and is followed by a long-lasting depression of neuronal activity. CSD was proposed to be the underlying phenomenon of the migraine aura as it propagates at a similar velocity with visual scotomata and the transient cortical oligemia seen in migraineurs during the aura phase. This data, enabling a better understanding of migraine pathophysiology, will result in new insights into the treatment of other neurological disorders such as cerebrovascular disorders, transient global amnesia, traumatic brain injury, in whose pathophysiology CSD is supposed to take part, beside the treatment of migraine itself.

Authors+Show Affiliations

Department of Neurology, Faculty of Medicine, University of Kocaeli, Kocaeli, Turkey.No affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

tur

PubMed ID

17457710

Citation

Alemdar, Murat, and Macit Selekler. "[Migraine and Cortical Spreading Depression]." Agri : Agri (Algoloji) Dernegi'nin Yayin Organidir = the Journal of the Turkish Society of Algology, vol. 18, no. 4, 2006, pp. 24-30.
Alemdar M, Selekler M. [Migraine and cortical spreading depression]. Agri. 2006;18(4):24-30.
Alemdar, M., & Selekler, M. (2006). [Migraine and cortical spreading depression]. Agri : Agri (Algoloji) Dernegi'nin Yayin Organidir = the Journal of the Turkish Society of Algology, 18(4), pp. 24-30.
Alemdar M, Selekler M. [Migraine and Cortical Spreading Depression]. Agri. 2006;18(4):24-30. PubMed PMID: 17457710.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Migraine and cortical spreading depression]. AU - Alemdar,Murat, AU - Selekler,Macit, PY - 2007/4/26/pubmed PY - 2007/6/29/medline PY - 2007/4/26/entrez SP - 24 EP - 30 JF - Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology JO - Agri VL - 18 IS - 4 N2 - Migraine is an episodic headache disorder accompanied by various neurological, gastrointestinal and autonomic changes. In one fifth of the migraineurs, a neurological disturbance (visual, sensory or motor) appears during or before the development of the headache called migraine aura. Cortical spreading depression (CSD) is a transient neuronal depolarization that spreads across unilateral hemisphere from a focus and is followed by a long-lasting depression of neuronal activity. CSD was proposed to be the underlying phenomenon of the migraine aura as it propagates at a similar velocity with visual scotomata and the transient cortical oligemia seen in migraineurs during the aura phase. This data, enabling a better understanding of migraine pathophysiology, will result in new insights into the treatment of other neurological disorders such as cerebrovascular disorders, transient global amnesia, traumatic brain injury, in whose pathophysiology CSD is supposed to take part, beside the treatment of migraine itself. SN - 1300-0012 UR - https://www.unboundmedicine.com/medline/citation/17457710/[Migraine_and_cortical_spreading_depression]_ L2 - http://www.journalagent.com/pubmed/linkout.asp?ISSN=1300-0012&PMID=17457710 DB - PRIME DP - Unbound Medicine ER -