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Auditory-evoked potentials in bispectral index-guided anaesthesia for cardiac surgery.
Eur J Anaesthesiol. 2007 Jul; 24(7):571-9.EJ

Abstract

BACKGROUND AND OBJECTIVE

Midlatency auditory-evoked potentials, as measures of the anaesthetic state, were evaluated at similar levels of bispectral index in cardiac surgical patients maintained with either propofol or isoflurane anaesthesia.

METHODS

Twenty-four patients were randomly allocated to anaesthesia with propofol (n = 12) or isoflurane (n = 12). Bispectral index was maintained below 60 during surgery. Auditory-evoked potentials were collected before induction of anaesthesia, 10 min after intubation, 30 min after sternotomy, during cardiopulmonary bypass at the time of cross-clamping of the aorta and during stable mild hypothermia, after de-clamping of the aorta, and after the operation.

RESULTS

At the pre-determined time points, bispectral index values showed comparable depth of hypnosis in both groups. The latency of the Nb component of midlatency auditory-evoked potentials was significantly increased in the isoflurane group after intubation (P < 0.001) and that of both the Nb and the Pa components after sternotomy (P < 0.001) compared with the propofol group. No differences between the groups were detected with respect to haemodynamic variables. No patient reported recall of intraoperative events.

CONCLUSION

After intubation and surgical stimulation, when bispectral index was at a constant level, there was a difference in the Nb and Pa components of the midlatency auditory-evoked potentials between the two anaesthetic regimens, indicating a distinction in the state of anaesthesia. Our results suggest that the parallel use of these two electrophysiological methods can show differences in the components of anaesthesia between various anaesthesia methods in cardiac surgical patients.

Authors+Show Affiliations

Kuopio University Hospital, Anaesthesiology and Intensive Care Department, Kuopio, Finland. tadeusz.musialowicz@kuh.fiNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17462117

Citation

Musialowicz, T, et al. "Auditory-evoked Potentials in Bispectral Index-guided Anaesthesia for Cardiac Surgery." European Journal of Anaesthesiology, vol. 24, no. 7, 2007, pp. 571-9.
Musialowicz T, Niskanen M, Yppärilä-Wolters H, et al. Auditory-evoked potentials in bispectral index-guided anaesthesia for cardiac surgery. Eur J Anaesthesiol. 2007;24(7):571-9.
Musialowicz, T., Niskanen, M., Yppärilä-Wolters, H., Pöyhönen, M., Pitkänen, O., & Hynynen, M. (2007). Auditory-evoked potentials in bispectral index-guided anaesthesia for cardiac surgery. European Journal of Anaesthesiology, 24(7), 571-9.
Musialowicz T, et al. Auditory-evoked Potentials in Bispectral Index-guided Anaesthesia for Cardiac Surgery. Eur J Anaesthesiol. 2007;24(7):571-9. PubMed PMID: 17462117.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Auditory-evoked potentials in bispectral index-guided anaesthesia for cardiac surgery. AU - Musialowicz,T, AU - Niskanen,M, AU - Yppärilä-Wolters,H, AU - Pöyhönen,M, AU - Pitkänen,O, AU - Hynynen,M, Y1 - 2007/04/27/ PY - 2007/4/28/pubmed PY - 2007/8/1/medline PY - 2007/4/28/entrez SP - 571 EP - 9 JF - European journal of anaesthesiology JO - Eur J Anaesthesiol VL - 24 IS - 7 N2 - BACKGROUND AND OBJECTIVE: Midlatency auditory-evoked potentials, as measures of the anaesthetic state, were evaluated at similar levels of bispectral index in cardiac surgical patients maintained with either propofol or isoflurane anaesthesia. METHODS: Twenty-four patients were randomly allocated to anaesthesia with propofol (n = 12) or isoflurane (n = 12). Bispectral index was maintained below 60 during surgery. Auditory-evoked potentials were collected before induction of anaesthesia, 10 min after intubation, 30 min after sternotomy, during cardiopulmonary bypass at the time of cross-clamping of the aorta and during stable mild hypothermia, after de-clamping of the aorta, and after the operation. RESULTS: At the pre-determined time points, bispectral index values showed comparable depth of hypnosis in both groups. The latency of the Nb component of midlatency auditory-evoked potentials was significantly increased in the isoflurane group after intubation (P < 0.001) and that of both the Nb and the Pa components after sternotomy (P < 0.001) compared with the propofol group. No differences between the groups were detected with respect to haemodynamic variables. No patient reported recall of intraoperative events. CONCLUSION: After intubation and surgical stimulation, when bispectral index was at a constant level, there was a difference in the Nb and Pa components of the midlatency auditory-evoked potentials between the two anaesthetic regimens, indicating a distinction in the state of anaesthesia. Our results suggest that the parallel use of these two electrophysiological methods can show differences in the components of anaesthesia between various anaesthesia methods in cardiac surgical patients. SN - 0265-0215 UR - https://www.unboundmedicine.com/medline/citation/17462117/Auditory_evoked_potentials_in_bispectral_index_guided_anaesthesia_for_cardiac_surgery_ L2 - https://medlineplus.gov/coronaryarterybypasssurgery.html DB - PRIME DP - Unbound Medicine ER -