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Long-term exposure to solar ultraviolet radiation as a risk factor for age-related macular degeneration.
Coll Antropol 2007; 31 Suppl 1:33-8CA

Abstract

A clinical epidemiological study has been conducted as apart of research project investigating chronic exposure to solar ultraviolet radiation (UVR) as a factor contributing to the onset of age-related macular degeneration (ARMD). The study included 623 subjects older than 50 from two different geographic areas, one with high solar radiation (the island of Solta - Region 1) and the other (Zagreb and its surroundings - Region 2) with low solar radiation. Individual exposure to UVR was assessed according to global exposure to sunlight, on the basis detailed history of life-long exposure to sunlight, with special reference to professional history and geophysical specificities of the respective areas. Different grades of ARMD were based on the fundus photographs and flourescein angiography. Statistically significant relation was found between ARMD and mean daily exposure (in hours) to solar radiation in Region 1 (chi2 = 186.22; p = 0.000), Region 2 (chi2 = 25.66; p = 0.000) and in both regions together (chi2 = 216.43; p = 0.000). ARMD is more frequent in the subjects belonging to the Region 1 and with the same exposure to sunlight (8 hours and more) which goes in favor of their increased UVR exposure. The results support a relationship between long-term sunlight exposure and increased risk of ARMD.

Authors+Show Affiliations

Department of Ophthalmology, Split University School of Medicine, Split, Croatia. iplestina@krizine.kbsplit.hrNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17469746

Citation

Plestina-Borjan, Ivna, and Mery Klinger-Lasić. "Long-term Exposure to Solar Ultraviolet Radiation as a Risk Factor for Age-related Macular Degeneration." Collegium Antropologicum, vol. 31 Suppl 1, 2007, pp. 33-8.
Plestina-Borjan I, Klinger-Lasić M. Long-term exposure to solar ultraviolet radiation as a risk factor for age-related macular degeneration. Coll Antropol. 2007;31 Suppl 1:33-8.
Plestina-Borjan, I., & Klinger-Lasić, M. (2007). Long-term exposure to solar ultraviolet radiation as a risk factor for age-related macular degeneration. Collegium Antropologicum, 31 Suppl 1, pp. 33-8.
Plestina-Borjan I, Klinger-Lasić M. Long-term Exposure to Solar Ultraviolet Radiation as a Risk Factor for Age-related Macular Degeneration. Coll Antropol. 2007;31 Suppl 1:33-8. PubMed PMID: 17469746.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Long-term exposure to solar ultraviolet radiation as a risk factor for age-related macular degeneration. AU - Plestina-Borjan,Ivna, AU - Klinger-Lasić,Mery, PY - 2007/5/2/pubmed PY - 2007/6/26/medline PY - 2007/5/2/entrez SP - 33 EP - 8 JF - Collegium antropologicum JO - Coll Antropol VL - 31 Suppl 1 N2 - A clinical epidemiological study has been conducted as apart of research project investigating chronic exposure to solar ultraviolet radiation (UVR) as a factor contributing to the onset of age-related macular degeneration (ARMD). The study included 623 subjects older than 50 from two different geographic areas, one with high solar radiation (the island of Solta - Region 1) and the other (Zagreb and its surroundings - Region 2) with low solar radiation. Individual exposure to UVR was assessed according to global exposure to sunlight, on the basis detailed history of life-long exposure to sunlight, with special reference to professional history and geophysical specificities of the respective areas. Different grades of ARMD were based on the fundus photographs and flourescein angiography. Statistically significant relation was found between ARMD and mean daily exposure (in hours) to solar radiation in Region 1 (chi2 = 186.22; p = 0.000), Region 2 (chi2 = 25.66; p = 0.000) and in both regions together (chi2 = 216.43; p = 0.000). ARMD is more frequent in the subjects belonging to the Region 1 and with the same exposure to sunlight (8 hours and more) which goes in favor of their increased UVR exposure. The results support a relationship between long-term sunlight exposure and increased risk of ARMD. SN - 0350-6134 UR - https://www.unboundmedicine.com/medline/citation/17469746/Long_term_exposure_to_solar_ultraviolet_radiation_as_a_risk_factor_for_age_related_macular_degeneration_ L2 - http://www.diseaseinfosearch.org/result/4401 DB - PRIME DP - Unbound Medicine ER -