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Can bipolar disorder-specific neuropsychological impairments in children be identified?
J Consult Clin Psychol. 2007 Apr; 75(2):210-20.JC

Abstract

This study examined neuropsychological deficits among children with bipolar disorder while attending to its comorbidity with attention-deficit/hyperactivity disorder (ADHD). Seventy-three unmedicated children (ages 6-17 years) with Diagnostic and Statistical Manual of Mental Disorders (4th ed.; American Psychiatric Association, 1994) bipolar disorder plus ADHD (BPD + ADHD) were compared with 102 unmedicated children with ADHD without bipolar disorder, and 120 children without bipolar disorder or ADHD. Ninety-four percent of participants were Caucasian, 58% were male, and 42% were female. On average participants were of middle to upper socioeconomic status. Participants were assessed with a comprehensive neuropsychological battery and measures of academic achievement, school failure, and special education placement. Participants with BPD + ADHD and with ADHD were impaired in interference control, verbal learning, and arithmetic achievement and had higher rates of special school services. Across all of the measures of neuropsychological functioning, the only difference observed between youths with BPD + ADHD and youths with ADHD was that youths with BPD + ADHD performed more poorly on one measure of processing speed. Thus, comorbidity with ADHD may account for many of the neuropsychological deficits observed in children with bipolar disorder.

Authors+Show Affiliations

Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Cambridge, MA 02138, USA. ahenin@partners.orgNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17469879

Citation

Henin, Aude, et al. "Can Bipolar Disorder-specific Neuropsychological Impairments in Children Be Identified?" Journal of Consulting and Clinical Psychology, vol. 75, no. 2, 2007, pp. 210-20.
Henin A, Mick E, Biederman J, et al. Can bipolar disorder-specific neuropsychological impairments in children be identified? J Consult Clin Psychol. 2007;75(2):210-20.
Henin, A., Mick, E., Biederman, J., Fried, R., Wozniak, J., Faraone, S. V., Harrington, K., Davis, S., & Doyle, A. E. (2007). Can bipolar disorder-specific neuropsychological impairments in children be identified? Journal of Consulting and Clinical Psychology, 75(2), 210-20.
Henin A, et al. Can Bipolar Disorder-specific Neuropsychological Impairments in Children Be Identified. J Consult Clin Psychol. 2007;75(2):210-20. PubMed PMID: 17469879.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Can bipolar disorder-specific neuropsychological impairments in children be identified? AU - Henin,Aude, AU - Mick,Eric, AU - Biederman,Joseph, AU - Fried,Ronna, AU - Wozniak,Janet, AU - Faraone,Stephen V, AU - Harrington,Kara, AU - Davis,Stephanie, AU - Doyle,Alysa E, PY - 2007/5/2/pubmed PY - 2007/6/2/medline PY - 2007/5/2/entrez SP - 210 EP - 20 JF - Journal of consulting and clinical psychology JO - J Consult Clin Psychol VL - 75 IS - 2 N2 - This study examined neuropsychological deficits among children with bipolar disorder while attending to its comorbidity with attention-deficit/hyperactivity disorder (ADHD). Seventy-three unmedicated children (ages 6-17 years) with Diagnostic and Statistical Manual of Mental Disorders (4th ed.; American Psychiatric Association, 1994) bipolar disorder plus ADHD (BPD + ADHD) were compared with 102 unmedicated children with ADHD without bipolar disorder, and 120 children without bipolar disorder or ADHD. Ninety-four percent of participants were Caucasian, 58% were male, and 42% were female. On average participants were of middle to upper socioeconomic status. Participants were assessed with a comprehensive neuropsychological battery and measures of academic achievement, school failure, and special education placement. Participants with BPD + ADHD and with ADHD were impaired in interference control, verbal learning, and arithmetic achievement and had higher rates of special school services. Across all of the measures of neuropsychological functioning, the only difference observed between youths with BPD + ADHD and youths with ADHD was that youths with BPD + ADHD performed more poorly on one measure of processing speed. Thus, comorbidity with ADHD may account for many of the neuropsychological deficits observed in children with bipolar disorder. SN - 0022-006X UR - https://www.unboundmedicine.com/medline/citation/17469879/Can_bipolar_disorder_specific_neuropsychological_impairments_in_children_be_identified L2 - http://content.apa.org/journals/ccp/75/2/210 DB - PRIME DP - Unbound Medicine ER -