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Cleveland Clinic PediPump lamb cadaver fitting studies.
Artif Organs. 2007 May; 31(5):405-8.AO

Abstract

We are developing the PediPump, a magnetically suspended, mixed-flow pump, as an implantable pediatric ventricular assist device (VAD). Lamb cadaver fitting studies were performed to determine the optimal pump location and optimal design of the inflow and outflow conduits for chronic in vivo studies. A prototype of the PediPump right and left ventricular assist devices (RVAD and LVAD, respectively) were implanted via a sternotomy or left thoracotomy in four lamb cadavers (3.7-34.2 kg). Via a sternotomy, the RVAD and LVAD required long inflow cannulas when placed into the right or left thoracic cavities, respectively. Via a left thoracotomy, with both pumps implanted in the left thoracic cavity, the RVAD required a 70 degrees inflow cannula and a bent outflow graft while the LVAD required a 130 degrees inflow cannula and a straight outflow graft. In conclusion, left thoracotomy provided optimal fitting for both LVAD and RVAD for the small lamb model.

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Authors+Show Affiliations

Cingoz F
Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Fukamachi K
No affiliation info available
Ootaki Y
No affiliation info available
Kamohara K
No affiliation info available
Akiyama M
No affiliation info available
Ootaki C
No affiliation info available
Kopcak MW
No affiliation info available
Liu J
No affiliation info available
Noecker A
No affiliation info available
Dudzinski D
No affiliation info available
Smith WA
No affiliation info available
Duncan BW
No affiliation info available

MeSH

AnimalsChildEquipment DesignHeart-Assist DevicesHumansModels, AnimalProsthesis ImplantationSheepThoracotomyTomography, X-Ray Computed

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

17470212

Citation

Cingoz, Faruk, et al. "Cleveland Clinic PediPump Lamb Cadaver Fitting Studies." Artificial Organs, vol. 31, no. 5, 2007, pp. 405-8.
Cingoz F, Fukamachi K, Ootaki Y, et al. Cleveland Clinic PediPump lamb cadaver fitting studies. Artif Organs. 2007;31(5):405-8.
Cingoz, F., Fukamachi, K., Ootaki, Y., Kamohara, K., Akiyama, M., Ootaki, C., Kopcak, M. W., Liu, J., Noecker, A., Dudzinski, D., Smith, W. A., & Duncan, B. W. (2007). Cleveland Clinic PediPump lamb cadaver fitting studies. Artificial Organs, 31(5), 405-8.
Cingoz F, et al. Cleveland Clinic PediPump Lamb Cadaver Fitting Studies. Artif Organs. 2007;31(5):405-8. PubMed PMID: 17470212.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cleveland Clinic PediPump lamb cadaver fitting studies. AU - Cingoz,Faruk, AU - Fukamachi,Kiyotaka, AU - Ootaki,Yoshio, AU - Kamohara,Keiji, AU - Akiyama,Masatoshi, AU - Ootaki,Chiyo, AU - Kopcak,Michael W, AU - Liu,Jenny, AU - Noecker,Angela, AU - Dudzinski,Dave, AU - Smith,William A, AU - Duncan,Brian W, PY - 2007/5/2/pubmed PY - 2007/7/20/medline PY - 2007/5/2/entrez SP - 405 EP - 8 JF - Artificial organs JO - Artif Organs VL - 31 IS - 5 N2 - We are developing the PediPump, a magnetically suspended, mixed-flow pump, as an implantable pediatric ventricular assist device (VAD). Lamb cadaver fitting studies were performed to determine the optimal pump location and optimal design of the inflow and outflow conduits for chronic in vivo studies. A prototype of the PediPump right and left ventricular assist devices (RVAD and LVAD, respectively) were implanted via a sternotomy or left thoracotomy in four lamb cadavers (3.7-34.2 kg). Via a sternotomy, the RVAD and LVAD required long inflow cannulas when placed into the right or left thoracic cavities, respectively. Via a left thoracotomy, with both pumps implanted in the left thoracic cavity, the RVAD required a 70 degrees inflow cannula and a bent outflow graft while the LVAD required a 130 degrees inflow cannula and a straight outflow graft. In conclusion, left thoracotomy provided optimal fitting for both LVAD and RVAD for the small lamb model. SN - 0160-564X UR - https://www.unboundmedicine.com/medline/citation/17470212/Cleveland_Clinic_PediPump_lamb_cadaver_fitting_studies_ L2 - https://doi.org/10.1111/j.1525-1594.2007.00400.x DB - PRIME DP - Unbound Medicine ER -