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Therapy for head lice based on life cycle, resistance, and safety considerations.
Pediatrics. 2007 May; 119(5):965-74.Ped

Abstract

The timing of head lice maturation most favorable to their survival in the presence of anti-lice agents is the maximum time as an ovum (12 days) and the shortest possible time of maturing from newly hatched nymph to egg-laying adult (8.5 days). Pediculicides that are not reliably ovicidal (pyrethroids and lindane) require 2 to 3 treatment cycles to eradicate lice. Ovicidal therapies (malathion) require 1 to 2 treatments. Treatment with an agent to which there is genetic resistance is unproductive. In the United States, lice have become increasingly resistant to pyrethroids and lindane but not to malathion. Treatment with malathion has favorable efficacy and safety profiles and enables the immediate, safe return to school. Nit combing can be performed adjunctively. No-nit policies should be rendered obsolete.

Authors+Show Affiliations

Lebwohl M
Department of Dermatology, Mount Sinai School of Medicine, New York, NY 10029, USA.
Clark L
No affiliation info available
Levitt J
No affiliation info available

MeSH

AnimalsHumansInsecticide ResistanceInsecticidesLice InfestationsLife Cycle StagesMalathionPediculusPermethrin

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

17473098

Citation

Lebwohl, Mark, et al. "Therapy for Head Lice Based On Life Cycle, Resistance, and Safety Considerations." Pediatrics, vol. 119, no. 5, 2007, pp. 965-74.
Lebwohl M, Clark L, Levitt J. Therapy for head lice based on life cycle, resistance, and safety considerations. Pediatrics. 2007;119(5):965-74.
Lebwohl, M., Clark, L., & Levitt, J. (2007). Therapy for head lice based on life cycle, resistance, and safety considerations. Pediatrics, 119(5), 965-74.
Lebwohl M, Clark L, Levitt J. Therapy for Head Lice Based On Life Cycle, Resistance, and Safety Considerations. Pediatrics. 2007;119(5):965-74. PubMed PMID: 17473098.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Therapy for head lice based on life cycle, resistance, and safety considerations. AU - Lebwohl,Mark, AU - Clark,Lily, AU - Levitt,Jacob, PY - 2007/5/3/pubmed PY - 2007/5/30/medline PY - 2007/5/3/entrez SP - 965 EP - 74 JF - Pediatrics JO - Pediatrics VL - 119 IS - 5 N2 - The timing of head lice maturation most favorable to their survival in the presence of anti-lice agents is the maximum time as an ovum (12 days) and the shortest possible time of maturing from newly hatched nymph to egg-laying adult (8.5 days). Pediculicides that are not reliably ovicidal (pyrethroids and lindane) require 2 to 3 treatment cycles to eradicate lice. Ovicidal therapies (malathion) require 1 to 2 treatments. Treatment with an agent to which there is genetic resistance is unproductive. In the United States, lice have become increasingly resistant to pyrethroids and lindane but not to malathion. Treatment with malathion has favorable efficacy and safety profiles and enables the immediate, safe return to school. Nit combing can be performed adjunctively. No-nit policies should be rendered obsolete. SN - 1098-4275 UR - https://www.unboundmedicine.com/medline/citation/17473098/Therapy_for_head_lice_based_on_life_cycle_resistance_and_safety_considerations_ DB - PRIME DP - Unbound Medicine ER -