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Epithelial dysplasia in atrophic gastritis. Bioptical follow-up study.
Ital J Gastroenterol. 1991 Feb; 23(2):70-3.IJ

Abstract

Fifty-nine cases of gastric dysplasia (46 of which were mild, 11 moderate and 2 severe) were studied in relation to their association with atrophic gastritis and intestinal metaplasia. Atrophic gastritis was found in 39 cases (28 of which were mild, 10 moderate and 1 severe). Dysplasia was considered "persistent" when found of the same degree in at least two consecutive check-ups after initial diagnosis (13 cases); it was considered "progressive" if found more severe or evolving as cancer (5 cases) or "regressive" if detected in a lesser degree or no longer detected (13 cases). Sixteen of the 18 persistent or progressive cases of dysplasia were associated with atrophic gastritis, whereas 10 of the 13 cases with regressive dysplasia revealed no concomitant pattern of gastric mucosa atrophy (p less than 0.005). These findings suggest that dysplasia represents a truly pre-neoplastic change particularly when associated with atrophic gastritis and which must therefore be more carefully monitored.

Authors+Show Affiliations

Dipartimenti di Anatomia Pathologica, Università di Padova, Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

1747506

Citation

Rugge, M, et al. "Epithelial Dysplasia in Atrophic Gastritis. Bioptical Follow-up Study." The Italian Journal of Gastroenterology, vol. 23, no. 2, 1991, pp. 70-3.
Rugge M, Baffa R, Farinati F, et al. Epithelial dysplasia in atrophic gastritis. Bioptical follow-up study. Ital J Gastroenterol. 1991;23(2):70-3.
Rugge, M., Baffa, R., Farinati, F., Di Mario, F., Guido, M., Valiante, F., & Ninfo, V. (1991). Epithelial dysplasia in atrophic gastritis. Bioptical follow-up study. The Italian Journal of Gastroenterology, 23(2), 70-3.
Rugge M, et al. Epithelial Dysplasia in Atrophic Gastritis. Bioptical Follow-up Study. Ital J Gastroenterol. 1991;23(2):70-3. PubMed PMID: 1747506.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Epithelial dysplasia in atrophic gastritis. Bioptical follow-up study. AU - Rugge,M, AU - Baffa,R, AU - Farinati,F, AU - Di Mario,F, AU - Guido,M, AU - Valiante,F, AU - Ninfo,V, PY - 1991/2/1/pubmed PY - 1991/2/1/medline PY - 1991/2/1/entrez SP - 70 EP - 3 JF - The Italian journal of gastroenterology JO - Ital J Gastroenterol VL - 23 IS - 2 N2 - Fifty-nine cases of gastric dysplasia (46 of which were mild, 11 moderate and 2 severe) were studied in relation to their association with atrophic gastritis and intestinal metaplasia. Atrophic gastritis was found in 39 cases (28 of which were mild, 10 moderate and 1 severe). Dysplasia was considered "persistent" when found of the same degree in at least two consecutive check-ups after initial diagnosis (13 cases); it was considered "progressive" if found more severe or evolving as cancer (5 cases) or "regressive" if detected in a lesser degree or no longer detected (13 cases). Sixteen of the 18 persistent or progressive cases of dysplasia were associated with atrophic gastritis, whereas 10 of the 13 cases with regressive dysplasia revealed no concomitant pattern of gastric mucosa atrophy (p less than 0.005). These findings suggest that dysplasia represents a truly pre-neoplastic change particularly when associated with atrophic gastritis and which must therefore be more carefully monitored. SN - 0392-0623 UR - https://www.unboundmedicine.com/medline/citation/1747506/Epithelial_dysplasia_in_atrophic_gastritis__Bioptical_follow_up_study_ DB - PRIME DP - Unbound Medicine ER -