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Free radical scavenging phenylethanoid glycosides from Leucas indica Linn.
Nat Prod Res. 2007 Apr; 21(4):354-61.NP

Abstract

A new phenylethanoid glycoside, 2-(3,4-dihydroxyphenyl)-ethyl-O-alpha-L-rhamnopyranosyl-(1 --> 3)-O-alpha-L-rhamnopyranosyl-(1 --> 6)-4-O-E-feruloyl-beta-D-glucopyranoside (3-O-methyl poliu-moside, 1) along with five known phenylethanoid glycosides (2-6) were isolated from the aerial parts of Leucas indica Linn. The structure of compound 1 has been elucidated on the basis of spectral data. Compounds 1-6 exhibited significant antioxidant activity in 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical assay method. These compounds were also found to be moderate inhibitors of xanthine oxidase (XO) enzyme.

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Publisher Full Text

Authors+Show Affiliations

Mostafa M
Chemical Research Division, BCSIR Laboratories, Dhaka 1205, Bangladesh. mostafabcsir@yahoo.com
Nahar N
No affiliation info available
Mosihuzzaman M
No affiliation info available
Makhmoor T
No affiliation info available
Choudhary MI
No affiliation info available
Rahman AU
No affiliation info available

MeSH

BangladeshBiphenyl CompoundsEnzyme InhibitorsFree Radical ScavengersGlycosidesHydrazinesLamiaceaeNuclear Magnetic Resonance, BiomolecularOptical RotationPhenolsPicratesPlant ExtractsSpectrometry, Mass, Fast Atom BombardmentSpectrophotometry, InfraredSpectrophotometry, UltravioletXanthine Oxidase

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17479425

Citation

Mostafa, M, et al. "Free Radical Scavenging Phenylethanoid Glycosides From Leucas Indica Linn." Natural Product Research, vol. 21, no. 4, 2007, pp. 354-61.
Mostafa M, Nahar N, Mosihuzzaman M, et al. Free radical scavenging phenylethanoid glycosides from Leucas indica Linn. Nat Prod Res. 2007;21(4):354-61.
Mostafa, M., Nahar, N., Mosihuzzaman, M., Makhmoor, T., Choudhary, M. I., & Rahman, A. U. (2007). Free radical scavenging phenylethanoid glycosides from Leucas indica Linn. Natural Product Research, 21(4), 354-61.
Mostafa M, et al. Free Radical Scavenging Phenylethanoid Glycosides From Leucas Indica Linn. Nat Prod Res. 2007;21(4):354-61. PubMed PMID: 17479425.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Free radical scavenging phenylethanoid glycosides from Leucas indica Linn. AU - Mostafa,M, AU - Nahar,Nilufar, AU - Mosihuzzaman,M, AU - Makhmoor,Talat, AU - Choudhary,M Iqbal, AU - Rahman,Atta-Ur, PY - 2007/5/5/pubmed PY - 2007/7/6/medline PY - 2007/5/5/entrez SP - 354 EP - 61 JF - Natural product research JO - Nat Prod Res VL - 21 IS - 4 N2 - A new phenylethanoid glycoside, 2-(3,4-dihydroxyphenyl)-ethyl-O-alpha-L-rhamnopyranosyl-(1 --> 3)-O-alpha-L-rhamnopyranosyl-(1 --> 6)-4-O-E-feruloyl-beta-D-glucopyranoside (3-O-methyl poliu-moside, 1) along with five known phenylethanoid glycosides (2-6) were isolated from the aerial parts of Leucas indica Linn. The structure of compound 1 has been elucidated on the basis of spectral data. Compounds 1-6 exhibited significant antioxidant activity in 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical assay method. These compounds were also found to be moderate inhibitors of xanthine oxidase (XO) enzyme. SN - 1478-6419 UR - https://www.unboundmedicine.com/medline/citation/17479425/Free_radical_scavenging_phenylethanoid_glycosides_from_Leucas_indica_Linn_ L2 - https://www.tandfonline.com/doi/full/10.1080/14786410701194401 DB - PRIME DP - Unbound Medicine ER -