Bioactive compounds in cranberries and their role in prevention of urinary tract infections.Mol Nutr Food Res. 2007 Jun; 51(6):732-7.MN
Abstract
Cranberry (Vaccinium macrocarpon Ait.) ingestion has long been associated with prevention of urinary tract infections. The beneficial mechanism was historically thought to be due to the fruit acids causing a bacteriostatic effect in the urine. However, recently, a group of proanthocyanidins (PACs) with A-type linkages were isolated from cranberry which exhibit bacterial antiadhesion activity against both antibiotic susceptible and resistant strains of uropathogenic P-fimbriated Escherichia coli bacteria. The link between cranberry ingestion and maintenance of urinary tract health as well as the structural diversity, pharmacokinetics, quantification, and bacterial antiadhesion bioactivity of the A-linked cranberry PACs are reviewed.
Links
MeSH
Pub Type(s)
Journal Article
Review
Language
eng
PubMed ID
17487930
Citation
Howell, Amy B.. "Bioactive Compounds in Cranberries and Their Role in Prevention of Urinary Tract Infections." Molecular Nutrition & Food Research, vol. 51, no. 6, 2007, pp. 732-7.
Howell AB. Bioactive compounds in cranberries and their role in prevention of urinary tract infections. Mol Nutr Food Res. 2007;51(6):732-7.
Howell, A. B. (2007). Bioactive compounds in cranberries and their role in prevention of urinary tract infections. Molecular Nutrition & Food Research, 51(6), 732-7.
Howell AB. Bioactive Compounds in Cranberries and Their Role in Prevention of Urinary Tract Infections. Mol Nutr Food Res. 2007;51(6):732-7. PubMed PMID: 17487930.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Bioactive compounds in cranberries and their role in prevention of urinary tract infections.
A1 - Howell,Amy B,
PY - 2007/5/10/pubmed
PY - 2007/8/19/medline
PY - 2007/5/10/entrez
SP - 732
EP - 7
JF - Molecular nutrition & food research
JO - Mol Nutr Food Res
VL - 51
IS - 6
N2 - Cranberry (Vaccinium macrocarpon Ait.) ingestion has long been associated with prevention of urinary tract infections. The beneficial mechanism was historically thought to be due to the fruit acids causing a bacteriostatic effect in the urine. However, recently, a group of proanthocyanidins (PACs) with A-type linkages were isolated from cranberry which exhibit bacterial antiadhesion activity against both antibiotic susceptible and resistant strains of uropathogenic P-fimbriated Escherichia coli bacteria. The link between cranberry ingestion and maintenance of urinary tract health as well as the structural diversity, pharmacokinetics, quantification, and bacterial antiadhesion bioactivity of the A-linked cranberry PACs are reviewed.
SN - 1613-4125
UR - https://www.unboundmedicine.com/medline/citation/17487930/Bioactive_compounds_in_cranberries_and_their_role_in_prevention_of_urinary_tract_infections_
L2 - https://doi.org/10.1002/mnfr.200700038
DB - PRIME
DP - Unbound Medicine
ER -