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Seroprevalence of Helicobacter pylori infection among schoolchildren and teachers in Taiwan.
Helicobacter. 2007 Jun; 12(3):258-64.H

Abstract

BACKGROUND

Helicobacter pylori are associated with chronic antral gastritis that is related to duodenal ulcer, gastric ulcer, and probably gastric adenocarcinoma. Infection of H. pylori during childhood is considered an important risk factor for gastric carcinoma in adult life.

MATERIALS AND METHODS

To examine the epidemiologic characteristics of H. pylori infection among schoolchildren in central Taiwan, a community-based survey was carried out using stratified sampling in 10 elementary schools and three junior high schools including students and theirs teachers. Serum specimens of 1950 healthy schoolchildren (aged 9-15 years old) and 253 teachers who were randomly sampled were screened for the H. pylori antibodies by enzyme-linked immunosorbent assay. Statistical analysis was performed by using the SPSS for Windows statistical software system.

RESULTS

A total of 332 subjects were H. pylori antibodies positive, giving an overall prevalence of 15.1%. The age-specific seropositive rates were 11.0% in 9-12 years age group, 12.3% in 13-15 years age group, and 45.1% in the teacher group. The older the age, the higher the seroprevalence (OR = 11.53; 95% CI = 6.73-19.74; p < .001 for children vs. teachers). There was no difference in the seroprevalence of H. pylori infection by gender, ethnicity, geographical area, socioeconomic level, parental education, sibship size, family members, and source of drinking water.

CONCLUSION

The teachers had a much higher prevalence of H. pylori antibodies. The finding suggests that these teachers (adults) might be infected in their early childhood and implies that the poor environmental and hygienic conditions might be responsible for it. It seemed that poor water supply system, sewage disposal, and other environmental hygiene in adult might play some roles in H. pylori infection in Taiwan (before early 1980s).

Authors+Show Affiliations

School of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung, Taiwan. ldb@csmu.edu.twNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17493007

Citation

Lin, Ding-Bang, et al. "Seroprevalence of Helicobacter Pylori Infection Among Schoolchildren and Teachers in Taiwan." Helicobacter, vol. 12, no. 3, 2007, pp. 258-64.
Lin DB, Lin JB, Chen CY, et al. Seroprevalence of Helicobacter pylori infection among schoolchildren and teachers in Taiwan. Helicobacter. 2007;12(3):258-64.
Lin, D. B., Lin, J. B., Chen, C. Y., Chen, S. C., & Chen, W. K. (2007). Seroprevalence of Helicobacter pylori infection among schoolchildren and teachers in Taiwan. Helicobacter, 12(3), 258-64.
Lin DB, et al. Seroprevalence of Helicobacter Pylori Infection Among Schoolchildren and Teachers in Taiwan. Helicobacter. 2007;12(3):258-64. PubMed PMID: 17493007.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Seroprevalence of Helicobacter pylori infection among schoolchildren and teachers in Taiwan. AU - Lin,Ding-Bang, AU - Lin,Jye-Bin, AU - Chen,Chien-Yi, AU - Chen,Shiuan-Chih, AU - Chen,Wen-Kang, PY - 2007/5/12/pubmed PY - 2007/7/26/medline PY - 2007/5/12/entrez SP - 258 EP - 64 JF - Helicobacter JO - Helicobacter VL - 12 IS - 3 N2 - BACKGROUND: Helicobacter pylori are associated with chronic antral gastritis that is related to duodenal ulcer, gastric ulcer, and probably gastric adenocarcinoma. Infection of H. pylori during childhood is considered an important risk factor for gastric carcinoma in adult life. MATERIALS AND METHODS: To examine the epidemiologic characteristics of H. pylori infection among schoolchildren in central Taiwan, a community-based survey was carried out using stratified sampling in 10 elementary schools and three junior high schools including students and theirs teachers. Serum specimens of 1950 healthy schoolchildren (aged 9-15 years old) and 253 teachers who were randomly sampled were screened for the H. pylori antibodies by enzyme-linked immunosorbent assay. Statistical analysis was performed by using the SPSS for Windows statistical software system. RESULTS: A total of 332 subjects were H. pylori antibodies positive, giving an overall prevalence of 15.1%. The age-specific seropositive rates were 11.0% in 9-12 years age group, 12.3% in 13-15 years age group, and 45.1% in the teacher group. The older the age, the higher the seroprevalence (OR = 11.53; 95% CI = 6.73-19.74; p < .001 for children vs. teachers). There was no difference in the seroprevalence of H. pylori infection by gender, ethnicity, geographical area, socioeconomic level, parental education, sibship size, family members, and source of drinking water. CONCLUSION: The teachers had a much higher prevalence of H. pylori antibodies. The finding suggests that these teachers (adults) might be infected in their early childhood and implies that the poor environmental and hygienic conditions might be responsible for it. It seemed that poor water supply system, sewage disposal, and other environmental hygiene in adult might play some roles in H. pylori infection in Taiwan (before early 1980s). SN - 1083-4389 UR - https://www.unboundmedicine.com/medline/citation/17493007/Seroprevalence_of_Helicobacter_pylori_infection_among_schoolchildren_and_teachers_in_Taiwan_ L2 - https://doi.org/10.1111/j.1523-5378.2007.00496.x DB - PRIME DP - Unbound Medicine ER -