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[Role of Cu, Zn- and Mn-containing superoxide dismutases during the yeast Saccharomyces cerevisiae growing on ethanol and glycerol].
Mikrobiol Z. 2007 Mar-Apr; 69(2):35-42.MZ

Abstract

Growth of the yeast Saccharomyces cerevisiae deficient as to superoxidedismutase (SOD) genes in the media containing ethanol or glycerol has been investigated. It was shown that the role of the two isoforms of SOD was different under conditions used in this study. The strain which has only mitochondrial Mn-SOD demonstrated higher velocity of culture growth on ethanol compared with the other strains investigated. In contrast to that, cytosolic Cu, Zn-SOD played more important role under growth on glycerol than Mn-SOD. The levels of carbonyl proteins in SOD-deficient strains grown on glycerol and in the cells of strain producing only Cu, Zn-SOD exposed to inhibitor diethyldithiocarbamate were investigated. The strains lacking Mn-SOD and Cu, Zn-SOD demonstrated virtually the same levels of carbonyl proteins. It is supposed that Cu, Zn-SOD can compensate Mn-SOD and vice versa. Nonlinear correlation between SOD activity and the level of carbonyl proteins was found that indicates to the uncertain role of SOD in protein oxidation.

Authors

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Pub Type(s)

Journal Article

Language

ukr

PubMed ID

17494333

Citation

Mandryk, S Ia, et al. "[Role of Cu, Zn- and Mn-containing Superoxide Dismutases During the Yeast Saccharomyces Cerevisiae Growing On Ethanol and Glycerol]." Mikrobiolohichnyi Zhurnal (Kiev, Ukraine : 1993), vol. 69, no. 2, 2007, pp. 35-42.
Mandryk SIa, Lushchak OV, Semchyshyn HM, et al. [Role of Cu, Zn- and Mn-containing superoxide dismutases during the yeast Saccharomyces cerevisiae growing on ethanol and glycerol]. Mikrobiol Z. 2007;69(2):35-42.
Mandryk, S. I. a., Lushchak, O. V., Semchyshyn, H. M., & Lushchak, V. I. (2007). [Role of Cu, Zn- and Mn-containing superoxide dismutases during the yeast Saccharomyces cerevisiae growing on ethanol and glycerol]. Mikrobiolohichnyi Zhurnal (Kiev, Ukraine : 1993), 69(2), 35-42.
Mandryk SIa, et al. [Role of Cu, Zn- and Mn-containing Superoxide Dismutases During the Yeast Saccharomyces Cerevisiae Growing On Ethanol and Glycerol]. Mikrobiol Z. 2007 Mar-Apr;69(2):35-42. PubMed PMID: 17494333.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Role of Cu, Zn- and Mn-containing superoxide dismutases during the yeast Saccharomyces cerevisiae growing on ethanol and glycerol]. AU - Mandryk,S Ia, AU - Lushchak,O V, AU - Semchyshyn,H M, AU - Lushchak,V I, PY - 2007/5/15/pubmed PY - 2007/5/26/medline PY - 2007/5/15/entrez SP - 35 EP - 42 JF - Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) JO - Mikrobiol Z VL - 69 IS - 2 N2 - Growth of the yeast Saccharomyces cerevisiae deficient as to superoxidedismutase (SOD) genes in the media containing ethanol or glycerol has been investigated. It was shown that the role of the two isoforms of SOD was different under conditions used in this study. The strain which has only mitochondrial Mn-SOD demonstrated higher velocity of culture growth on ethanol compared with the other strains investigated. In contrast to that, cytosolic Cu, Zn-SOD played more important role under growth on glycerol than Mn-SOD. The levels of carbonyl proteins in SOD-deficient strains grown on glycerol and in the cells of strain producing only Cu, Zn-SOD exposed to inhibitor diethyldithiocarbamate were investigated. The strains lacking Mn-SOD and Cu, Zn-SOD demonstrated virtually the same levels of carbonyl proteins. It is supposed that Cu, Zn-SOD can compensate Mn-SOD and vice versa. Nonlinear correlation between SOD activity and the level of carbonyl proteins was found that indicates to the uncertain role of SOD in protein oxidation. SN - 1028-0987 UR - https://www.unboundmedicine.com/medline/citation/17494333/[Role_of_Cu_Zn__and_Mn_containing_superoxide_dismutases_during_the_yeast_Saccharomyces_cerevisiae_growing_on_ethanol_and_glycerol]_ L2 - https://www.yeastgenome.org/reference/17494333 DB - PRIME DP - Unbound Medicine ER -