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Percentage non-caeruloplasmin bound copper.
Clin Biochem. 2007 Jun; 40(9-10):749-50.CB

Abstract

OBJECTIVES

To compare percentage non-caeruloplasmin bound copper (%NCC) to generally accepted values.

DESIGN AND METHODS

Using data for 338 normal individual patients, we calculated the %NCC.

RESULTS

The %NCC ranged (median) from -59.75% to 51.98% (8.75%) respectively. The non-parametric reference interval was -23.44% to 22.99% with 43.8% of the %NCC values >10%.

CONCLUSIONS

We found the %NCC to be higher than generally accepted. This may be due to uncertainty from precision, bias and specificity.

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Authors+Show Affiliations

Twomey PJ
Department of Clinical Biochemistry, The Ipswich Hospital, Heath Road, Ipswich IP4 5PD, UK. patrick.twomey@ipswichhospital.nhs.uk
Wierzbicki AS
No affiliation info available
House IM
No affiliation info available
Viljoen A
No affiliation info available
Reynolds TM
No affiliation info available

MeSH

CeruloplasminCopperHumansProtein BindingReference Values

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17498678

Citation

Twomey, Patrick J., et al. "Percentage Non-caeruloplasmin Bound Copper." Clinical Biochemistry, vol. 40, no. 9-10, 2007, pp. 749-50.
Twomey PJ, Wierzbicki AS, House IM, et al. Percentage non-caeruloplasmin bound copper. Clin Biochem. 2007;40(9-10):749-50.
Twomey, P. J., Wierzbicki, A. S., House, I. M., Viljoen, A., & Reynolds, T. M. (2007). Percentage non-caeruloplasmin bound copper. Clinical Biochemistry, 40(9-10), 749-50.
Twomey PJ, et al. Percentage Non-caeruloplasmin Bound Copper. Clin Biochem. 2007;40(9-10):749-50. PubMed PMID: 17498678.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Percentage non-caeruloplasmin bound copper. AU - Twomey,Patrick J, AU - Wierzbicki,Anthony S, AU - House,Ivan M, AU - Viljoen,Adie, AU - Reynolds,Timothy M, Y1 - 2007/04/19/ PY - 2007/02/02/received PY - 2007/04/02/revised PY - 2007/04/09/accepted PY - 2007/5/15/pubmed PY - 2007/7/24/medline PY - 2007/5/15/entrez SP - 749 EP - 50 JF - Clinical biochemistry JO - Clin Biochem VL - 40 IS - 9-10 N2 - OBJECTIVES: To compare percentage non-caeruloplasmin bound copper (%NCC) to generally accepted values. DESIGN AND METHODS: Using data for 338 normal individual patients, we calculated the %NCC. RESULTS: The %NCC ranged (median) from -59.75% to 51.98% (8.75%) respectively. The non-parametric reference interval was -23.44% to 22.99% with 43.8% of the %NCC values >10%. CONCLUSIONS: We found the %NCC to be higher than generally accepted. This may be due to uncertainty from precision, bias and specificity. SN - 0009-9120 UR - https://www.unboundmedicine.com/medline/citation/17498678/Percentage_non_caeruloplasmin_bound_copper_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0009-9120(07)00168-3 DB - PRIME DP - Unbound Medicine ER -