Tags

Type your tag names separated by a space and hit enter

Impact of unilateral sural nerve graft on recovery of potency and continence following radical prostatectomy: 3-year longitudinal study.
J Urol. 2007 Jul; 178(1):212-6; discussion 216.JU

Abstract

PURPOSE

We conducted a 3-year longitudinal study assessing the impact of unilateral sural nerve graft on recovery of potency and continence following radical prostatectomy.

MATERIALS AND METHODS

A total of 113 patients undergoing radical retropubic prostatectomy were classified into 3 groups according to the degree of nerve sparing, that is unilateral nerve preservation with contralateral sural nerve graft interposition, bilateral nerve sparing and unilateral nerve sparing. Urinary continence and potency were estimated by the UCLA Prostate Cancer Index questionnaire.

RESULTS

Patients in the nerve sparing plus sural nerve graft group were younger than those in the bilateral nerve sparing or unilateral nerve sparing groups. At baseline the unilateral nerve sparing plus sural nerve graft group and the bilateral nerve sparing group reported better sexual function than the unilateral nerve sparing group (62.1 and 61.5 vs 49.9, p<0.05). The bilateral nerve sparing group showed more rapid recovery than the unilateral nerve sparing plus sural nerve graft group after radical retropubic prostatectomy (p<0.01). After 24 months there were no significant differences observed between the bilateral nerve sparing and the unilateral nerve sparing plus sural nerve graft group (28.7 vs 32.9). The bilateral nerve sparing group reported a better sexual function score than the unilateral nerve sparing group throughout the postoperative period (p<0.05). The bilateral nerve sparing group maintained significantly better urinary function at 1 month after radical retropubic prostatectomy than the unilateral nerve sparing plus sural nerve graft group (p <0.05). After 3 months these groups were almost continent. The unilateral nerve sparing group reported lower urinary function scores during the first year compared to the other groups.

CONCLUSIONS

The nerve graft procedure may contribute to the recovery of urinary function as well as sexual function after radical retropubic prostatectomy. This finding needs to be validated in a randomized trial.

Authors+Show Affiliations

Department of Urology, Tohoku University Graduate School of Medicine, Tohoku, Japan. namikin@uro.med.tohoku.ac.jpNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17499797

Citation

Namiki, Shunichi, et al. "Impact of Unilateral Sural Nerve Graft On Recovery of Potency and Continence Following Radical Prostatectomy: 3-year Longitudinal Study." The Journal of Urology, vol. 178, no. 1, 2007, pp. 212-6; discussion 216.
Namiki S, Saito S, Nakagawa H, et al. Impact of unilateral sural nerve graft on recovery of potency and continence following radical prostatectomy: 3-year longitudinal study. J Urol. 2007;178(1):212-6; discussion 216.
Namiki, S., Saito, S., Nakagawa, H., Sanada, T., Yamada, A., & Arai, Y. (2007). Impact of unilateral sural nerve graft on recovery of potency and continence following radical prostatectomy: 3-year longitudinal study. The Journal of Urology, 178(1), 212-6; discussion 216.
Namiki S, et al. Impact of Unilateral Sural Nerve Graft On Recovery of Potency and Continence Following Radical Prostatectomy: 3-year Longitudinal Study. J Urol. 2007;178(1):212-6; discussion 216. PubMed PMID: 17499797.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Impact of unilateral sural nerve graft on recovery of potency and continence following radical prostatectomy: 3-year longitudinal study. AU - Namiki,Shunichi, AU - Saito,Seiichi, AU - Nakagawa,Haruo, AU - Sanada,Takehiko, AU - Yamada,Atsushi, AU - Arai,Yoichi, Y1 - 2007/05/17/ PY - 2006/11/27/received PY - 2007/5/15/pubmed PY - 2007/7/18/medline PY - 2007/5/15/entrez SP - 212-6; discussion 216 JF - The Journal of urology JO - J Urol VL - 178 IS - 1 N2 - PURPOSE: We conducted a 3-year longitudinal study assessing the impact of unilateral sural nerve graft on recovery of potency and continence following radical prostatectomy. MATERIALS AND METHODS: A total of 113 patients undergoing radical retropubic prostatectomy were classified into 3 groups according to the degree of nerve sparing, that is unilateral nerve preservation with contralateral sural nerve graft interposition, bilateral nerve sparing and unilateral nerve sparing. Urinary continence and potency were estimated by the UCLA Prostate Cancer Index questionnaire. RESULTS: Patients in the nerve sparing plus sural nerve graft group were younger than those in the bilateral nerve sparing or unilateral nerve sparing groups. At baseline the unilateral nerve sparing plus sural nerve graft group and the bilateral nerve sparing group reported better sexual function than the unilateral nerve sparing group (62.1 and 61.5 vs 49.9, p<0.05). The bilateral nerve sparing group showed more rapid recovery than the unilateral nerve sparing plus sural nerve graft group after radical retropubic prostatectomy (p<0.01). After 24 months there were no significant differences observed between the bilateral nerve sparing and the unilateral nerve sparing plus sural nerve graft group (28.7 vs 32.9). The bilateral nerve sparing group reported a better sexual function score than the unilateral nerve sparing group throughout the postoperative period (p<0.05). The bilateral nerve sparing group maintained significantly better urinary function at 1 month after radical retropubic prostatectomy than the unilateral nerve sparing plus sural nerve graft group (p <0.05). After 3 months these groups were almost continent. The unilateral nerve sparing group reported lower urinary function scores during the first year compared to the other groups. CONCLUSIONS: The nerve graft procedure may contribute to the recovery of urinary function as well as sexual function after radical retropubic prostatectomy. This finding needs to be validated in a randomized trial. SN - 0022-5347 UR - https://www.unboundmedicine.com/medline/citation/17499797/Impact_of_unilateral_sural_nerve_graft_on_recovery_of_potency_and_continence_following_radical_prostatectomy:_3_year_longitudinal_study_ L2 - https://www.jurology.com/doi/10.1016/j.juro.2007.03.043?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -