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Risk analysis of coronary heart diseases in Korean adults by using the National Cholesterol Education Program Adult Treatment Panel III.

Abstract

The National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III), updated in 2001, quantified the risk factors and made it possible to assess risks for metabolic syndrome (MS) and coronary heart diseases (CHD). Many reported the prevalence of MS by NCEP ATP III in Orientals but few did risk analysis of CHD. We investigated the risk of CHD in Korean adults and the distribution of population for therapeutic lifestyle change (TLC) and drug therapy according to the NCEP ATP III guidelines. Based on ATP III risk factors, estimates of the 10-year risk for CHD on 16,383 Koreans and the distributions of population for the TLC and additional drug therapy by sex and age were calculated. High-, intermediate-, and low-risk groups were 8.1%, 24.1%, and 67.8%, respectively; 12.1% (high-, intermediate-, and low-risk groups: 32.0%, 45.1%, and 6.0%, respectively) needed TLC and 6.1% (high-, intermediate-, and low-risk groups: 39.4%, 16.6%, and 1.3%, respectively) needed additional drug therapy. The groups with higher risk needed more TLC and drug therapy. In the same age group, the rates of high risk in men showed a 1.0-6.6 fold increase compared with those in women. In Koreans, those who needed TLC and drug therapy were substantially lower than those in Americans.

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  • Authors+Show Affiliations

    ,

    Department of Laboratory Medicine, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea.

    , , , , ,

    Source

    MeSH

    Adult
    Aged
    C-Reactive Protein
    Cholesterol, HDL
    Cholesterol, LDL
    Coronary Disease
    Female
    Health Behavior
    Humans
    Life Style
    Male
    Middle Aged
    Risk Assessment
    Risk Factors
    Triglycerides

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    17506476

    Citation

    Lee, Yong-Wha, et al. "Risk Analysis of Coronary Heart Diseases in Korean Adults By Using the National Cholesterol Education Program Adult Treatment Panel III." Journal of Clinical Laboratory Analysis, vol. 21, no. 3, 2007, pp. 178-82.
    Lee YW, Min WK, Lee W, et al. Risk analysis of coronary heart diseases in Korean adults by using the National Cholesterol Education Program Adult Treatment Panel III. J Clin Lab Anal. 2007;21(3):178-82.
    Lee, Y. W., Min, W. K., Lee, W., Chun, S., Park, H., Lee, D. H., & Lee, Y. K. (2007). Risk analysis of coronary heart diseases in Korean adults by using the National Cholesterol Education Program Adult Treatment Panel III. Journal of Clinical Laboratory Analysis, 21(3), pp. 178-82.
    Lee YW, et al. Risk Analysis of Coronary Heart Diseases in Korean Adults By Using the National Cholesterol Education Program Adult Treatment Panel III. J Clin Lab Anal. 2007;21(3):178-82. PubMed PMID: 17506476.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Risk analysis of coronary heart diseases in Korean adults by using the National Cholesterol Education Program Adult Treatment Panel III. AU - Lee,Yong-Wha, AU - Min,Won-Ki, AU - Lee,Woochang, AU - Chun,Sail, AU - Park,Hyosoon, AU - Lee,Do-Hoon, AU - Lee,You Kyoung, PY - 2007/5/18/pubmed PY - 2007/7/4/medline PY - 2007/5/18/entrez SP - 178 EP - 82 JF - Journal of clinical laboratory analysis JO - J. Clin. Lab. Anal. VL - 21 IS - 3 N2 - The National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III), updated in 2001, quantified the risk factors and made it possible to assess risks for metabolic syndrome (MS) and coronary heart diseases (CHD). Many reported the prevalence of MS by NCEP ATP III in Orientals but few did risk analysis of CHD. We investigated the risk of CHD in Korean adults and the distribution of population for therapeutic lifestyle change (TLC) and drug therapy according to the NCEP ATP III guidelines. Based on ATP III risk factors, estimates of the 10-year risk for CHD on 16,383 Koreans and the distributions of population for the TLC and additional drug therapy by sex and age were calculated. High-, intermediate-, and low-risk groups were 8.1%, 24.1%, and 67.8%, respectively; 12.1% (high-, intermediate-, and low-risk groups: 32.0%, 45.1%, and 6.0%, respectively) needed TLC and 6.1% (high-, intermediate-, and low-risk groups: 39.4%, 16.6%, and 1.3%, respectively) needed additional drug therapy. The groups with higher risk needed more TLC and drug therapy. In the same age group, the rates of high risk in men showed a 1.0-6.6 fold increase compared with those in women. In Koreans, those who needed TLC and drug therapy were substantially lower than those in Americans. SN - 0887-8013 UR - https://www.unboundmedicine.com/medline/citation/17506476/Risk_analysis_of_coronary_heart_diseases_in_Korean_adults_by_using_the_National_Cholesterol_Education_Program_Adult_Treatment_Panel_III_ L2 - https://doi.org/10.1002/jcla.20165 DB - PRIME DP - Unbound Medicine ER -