Tags

Type your tag names separated by a space and hit enter

Neuropsychological and behavioural disinhibition in adult ADHD compared to borderline personality disorder.
Psychol Med. 2007 Dec; 37(12):1717-29.PM

Abstract

BACKGROUND

Although attention-deficit/hyperactivity disorder (ADHD) is thought to be an inhibitory disorder, the question remains of how specific the inhibitory deficit is in adults and whether it distinguishes ADHD from borderline personality disorder (BPD), with which it shares several clinical features, particularly impulsiveness.

METHOD

The study assessed various motor and cognitive inhibitory functions (inhibition of prepotent, ongoing and interfering responses) in addition to working memory in adult ADHD patients with and without BPD, compared to subjects with BPD alone and controls. In addition, questionnaire data on various aspects of impulsiveness and anger regulation were assessed in all groups.

RESULTS

ADHD patients performed worse than BPD individuals and controls in two inhibitory tasks: the stop signal task and the conflict module of the Attentional Network Task (ANT). In addition, they exhibited longer reaction times (RTs) and higher intra-individual variance in nearly all attentional tasks. The co-morbid group exhibited poor performance on the stop signal task but not on the conflict task. The BPD group barely differed from controls in neuropsychological performance but overlapped with ADHD in some behavioural problems, although they were less severe on the whole.

CONCLUSIONS

Impaired inhibition is a core feature in adults with ADHD. In addition, slow RTs and high intra-individual variance in performance may reflect deficits in the regulation of activation and effort in ADHD patients. ADHD and BPD share some symptoms of behavioural dysregulation without common cognitive deficits, at least in the attentional realm.

Authors+Show Affiliations

Department of Psychiatry and Psychotherapy, RWTH Aachen, University Hospital, Rostock, Germany.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17506923

Citation

Lampe, K, et al. "Neuropsychological and Behavioural Disinhibition in Adult ADHD Compared to Borderline Personality Disorder." Psychological Medicine, vol. 37, no. 12, 2007, pp. 1717-29.
Lampe K, Konrad K, Kroener S, et al. Neuropsychological and behavioural disinhibition in adult ADHD compared to borderline personality disorder. Psychol Med. 2007;37(12):1717-29.
Lampe, K., Konrad, K., Kroener, S., Fast, K., Kunert, H. J., & Herpertz, S. C. (2007). Neuropsychological and behavioural disinhibition in adult ADHD compared to borderline personality disorder. Psychological Medicine, 37(12), 1717-29.
Lampe K, et al. Neuropsychological and Behavioural Disinhibition in Adult ADHD Compared to Borderline Personality Disorder. Psychol Med. 2007;37(12):1717-29. PubMed PMID: 17506923.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Neuropsychological and behavioural disinhibition in adult ADHD compared to borderline personality disorder. AU - Lampe,K, AU - Konrad,K, AU - Kroener,S, AU - Fast,K, AU - Kunert,H J, AU - Herpertz,S C, Y1 - 2007/05/17/ PY - 2007/5/18/pubmed PY - 2008/3/5/medline PY - 2007/5/18/entrez SP - 1717 EP - 29 JF - Psychological medicine JO - Psychol Med VL - 37 IS - 12 N2 - BACKGROUND: Although attention-deficit/hyperactivity disorder (ADHD) is thought to be an inhibitory disorder, the question remains of how specific the inhibitory deficit is in adults and whether it distinguishes ADHD from borderline personality disorder (BPD), with which it shares several clinical features, particularly impulsiveness. METHOD: The study assessed various motor and cognitive inhibitory functions (inhibition of prepotent, ongoing and interfering responses) in addition to working memory in adult ADHD patients with and without BPD, compared to subjects with BPD alone and controls. In addition, questionnaire data on various aspects of impulsiveness and anger regulation were assessed in all groups. RESULTS: ADHD patients performed worse than BPD individuals and controls in two inhibitory tasks: the stop signal task and the conflict module of the Attentional Network Task (ANT). In addition, they exhibited longer reaction times (RTs) and higher intra-individual variance in nearly all attentional tasks. The co-morbid group exhibited poor performance on the stop signal task but not on the conflict task. The BPD group barely differed from controls in neuropsychological performance but overlapped with ADHD in some behavioural problems, although they were less severe on the whole. CONCLUSIONS: Impaired inhibition is a core feature in adults with ADHD. In addition, slow RTs and high intra-individual variance in performance may reflect deficits in the regulation of activation and effort in ADHD patients. ADHD and BPD share some symptoms of behavioural dysregulation without common cognitive deficits, at least in the attentional realm. SN - 0033-2917 UR - https://www.unboundmedicine.com/medline/citation/17506923/Neuropsychological_and_behavioural_disinhibition_in_adult_ADHD_compared_to_borderline_personality_disorder_ L2 - https://www.cambridge.org/core/product/identifier/S0033291707000517/type/journal_article DB - PRIME DP - Unbound Medicine ER -