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[Duration of untreated psychosis as predictive and prognostic factor in the course of first episode psychosis].
Actas Esp Psiquiatr. 2007 May-Jun; 35(3):162-9.AE

Abstract

INTRODUCTION

Recently, many studies have focused on the duration of untreated psychosis (DUP) in order to clarify if DUP could be one of the factors that would influence prognosis of psychotic disease.

MATERIAL AND METHODS

We present a one year follow - up study with 90 medication native, first episode psychotic patients. The likely prognosis factors that could influence in the outcome of the disease were measured. Therefore, we used a protocol including the following scales: PANSS, Psychosocial Stress Global Assessment scale (DSM IIIR), Global Assessment of Functioning scale (GAF-EEAG), Clinical Global Impression (CGI), Montgomery-Asberg scale for the depression, Young mania rating scale, abnormal involuntary movements scale, UKU scale for extrapyramidal symptoms and Premorbid Adjustment scale (Cannon-Spoor). Assessments were made every three months for 1 year. A statistical analysis of data was performed.

RESULTS

As a result, it was concluded that there was no relationship between a long duration untreated psychosis and a worse outcome of the illness in our sample. The only related factors with the prognosis were premorbid adjustment and the type of disease onset. Hence, the patients with a better premorbid adjustment and an acute onset of psychosis had a better outcome.

CONCLUSION

Our study represents more evidence in favor of the independence of DUP and disease outcome.

Authors+Show Affiliations

Servicio de Psiquiatría, Hospital de Cruces, Baracaldo (Vizcaya). anacatalan@bilbao.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

spa

PubMed ID

17508292

Citation

Alcántara, Catalán A., et al. "[Duration of Untreated Psychosis as Predictive and Prognostic Factor in the Course of First Episode Psychosis]." Actas Espanolas De Psiquiatria, vol. 35, no. 3, 2007, pp. 162-9.
Alcántara CA, Echevarría SR, Uruchurtu EI, et al. [Duration of untreated psychosis as predictive and prognostic factor in the course of first episode psychosis]. Actas Esp Psiquiatr. 2007;35(3):162-9.
Alcántara, C. A., Echevarría, S. R., Uruchurtu, E. I., Marañón, R. M., Pérez, S. M., Etxebeste, P. M., Fraile, G. M., & Gómez, F. C. (2007). [Duration of untreated psychosis as predictive and prognostic factor in the course of first episode psychosis]. Actas Espanolas De Psiquiatria, 35(3), 162-9.
Alcántara CA, et al. [Duration of Untreated Psychosis as Predictive and Prognostic Factor in the Course of First Episode Psychosis]. Actas Esp Psiquiatr. 2007 May-Jun;35(3):162-9. PubMed PMID: 17508292.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Duration of untreated psychosis as predictive and prognostic factor in the course of first episode psychosis]. AU - Alcántara,Catalán A, AU - Echevarría,Segarra R, AU - Uruchurtu,Eguíluz I, AU - Marañón,Rodríguez M, AU - Pérez,Sánchez M, AU - Etxebeste,Prieto M, AU - Fraile,Gutiérrez M, AU - Gómez,Fernández C, PY - 2007/5/18/pubmed PY - 2007/9/7/medline PY - 2007/5/18/entrez SP - 162 EP - 9 JF - Actas espanolas de psiquiatria JO - Actas Esp Psiquiatr VL - 35 IS - 3 N2 - INTRODUCTION: Recently, many studies have focused on the duration of untreated psychosis (DUP) in order to clarify if DUP could be one of the factors that would influence prognosis of psychotic disease. MATERIAL AND METHODS: We present a one year follow - up study with 90 medication native, first episode psychotic patients. The likely prognosis factors that could influence in the outcome of the disease were measured. Therefore, we used a protocol including the following scales: PANSS, Psychosocial Stress Global Assessment scale (DSM IIIR), Global Assessment of Functioning scale (GAF-EEAG), Clinical Global Impression (CGI), Montgomery-Asberg scale for the depression, Young mania rating scale, abnormal involuntary movements scale, UKU scale for extrapyramidal symptoms and Premorbid Adjustment scale (Cannon-Spoor). Assessments were made every three months for 1 year. A statistical analysis of data was performed. RESULTS: As a result, it was concluded that there was no relationship between a long duration untreated psychosis and a worse outcome of the illness in our sample. The only related factors with the prognosis were premorbid adjustment and the type of disease onset. Hence, the patients with a better premorbid adjustment and an acute onset of psychosis had a better outcome. CONCLUSION: Our study represents more evidence in favor of the independence of DUP and disease outcome. SN - 1139-9287 UR - https://www.unboundmedicine.com/medline/citation/17508292/[Duration_of_untreated_psychosis_as_predictive_and_prognostic_factor_in_the_course_of_first_episode_psychosis]_ L2 - https://medlineplus.gov/psychoticdisorders.html DB - PRIME DP - Unbound Medicine ER -