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Diagnostic stability 2 years after treatment initiation in the early psychosis intervention programme in Singapore.
Aust N Z J Psychiatry. 2007 Jun; 41(6):495-500.AN

Abstract

OBJECTIVE

To evaluate the diagnostic stability of psychotic disorders over a 2 year period in patients presenting with first-episode psychosis.

METHODS

One hundred and fifty-four patients were recruited from an early psychosis intervention programme (EPIP). They were diagnosed by the attending psychiatrist using the Structured Clinical Interview for DSM-IV Axis I at first contact (baseline) and after 24 months. The diagnoses were classified into the following categories: schizophrenia spectrum disorders (schizophrenia, schizophreniform disorder and schizoaffective disorder), affective psychosis (bipolar and major depressive disorders with psychotic symptoms), and other non-affective psychosis (delusional disorder, psychosis not otherwise specified and brief psychotic disorder). Two measures of stability, the prospective and the retrospective consistency were determined for each diagnosis.

RESULTS

The diagnoses with the best prospective consistency were schizophrenia (87.0%) and affective psychosis (54.5%). The shift into schizophrenia spectrum disorder was the most frequent diagnostic change. Duration of untreated psychosis was found to be the only significant predictor of shift.

CONCLUSION

It is difficult to make a definitive diagnosis at first contact. The clinical need to review the diagnosis throughout the period of follow up is emphasized.

Authors+Show Affiliations

Institute of Mental Health, 10 Buangkok View, Singapore.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17508319

Citation

Subramaniam, Mythily, et al. "Diagnostic Stability 2 Years After Treatment Initiation in the Early Psychosis Intervention Programme in Singapore." The Australian and New Zealand Journal of Psychiatry, vol. 41, no. 6, 2007, pp. 495-500.
Subramaniam M, Pek E, Verma S, et al. Diagnostic stability 2 years after treatment initiation in the early psychosis intervention programme in Singapore. Aust N Z J Psychiatry. 2007;41(6):495-500.
Subramaniam, M., Pek, E., Verma, S., Chan, Y. H., & Chong, S. A. (2007). Diagnostic stability 2 years after treatment initiation in the early psychosis intervention programme in Singapore. The Australian and New Zealand Journal of Psychiatry, 41(6), 495-500.
Subramaniam M, et al. Diagnostic Stability 2 Years After Treatment Initiation in the Early Psychosis Intervention Programme in Singapore. Aust N Z J Psychiatry. 2007;41(6):495-500. PubMed PMID: 17508319.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diagnostic stability 2 years after treatment initiation in the early psychosis intervention programme in Singapore. AU - Subramaniam,Mythily, AU - Pek,Elaine, AU - Verma,Swapna, AU - Chan,Yiong Huak, AU - Chong,Siow Ann, PY - 2007/5/18/pubmed PY - 2007/8/24/medline PY - 2007/5/18/entrez SP - 495 EP - 500 JF - The Australian and New Zealand journal of psychiatry JO - Aust N Z J Psychiatry VL - 41 IS - 6 N2 - OBJECTIVE: To evaluate the diagnostic stability of psychotic disorders over a 2 year period in patients presenting with first-episode psychosis. METHODS: One hundred and fifty-four patients were recruited from an early psychosis intervention programme (EPIP). They were diagnosed by the attending psychiatrist using the Structured Clinical Interview for DSM-IV Axis I at first contact (baseline) and after 24 months. The diagnoses were classified into the following categories: schizophrenia spectrum disorders (schizophrenia, schizophreniform disorder and schizoaffective disorder), affective psychosis (bipolar and major depressive disorders with psychotic symptoms), and other non-affective psychosis (delusional disorder, psychosis not otherwise specified and brief psychotic disorder). Two measures of stability, the prospective and the retrospective consistency were determined for each diagnosis. RESULTS: The diagnoses with the best prospective consistency were schizophrenia (87.0%) and affective psychosis (54.5%). The shift into schizophrenia spectrum disorder was the most frequent diagnostic change. Duration of untreated psychosis was found to be the only significant predictor of shift. CONCLUSION: It is difficult to make a definitive diagnosis at first contact. The clinical need to review the diagnosis throughout the period of follow up is emphasized. SN - 0004-8674 UR - https://www.unboundmedicine.com/medline/citation/17508319/Diagnostic_stability_2_years_after_treatment_initiation_in_the_early_psychosis_intervention_programme_in_Singapore_ L2 - https://journals.sagepub.com/doi/10.1080/00048670701332276?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -