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Development of new probiotics by strain combinations: is it possible to improve the adhesion to intestinal mucus?
J Dairy Sci 2007; 90(6):2710-6JD

Abstract

We evaluated the ability of commercial probiotic strains (Lactobacillus rhamnosus GG, L. rhamnosus LC705, Bifidobacterium breve 99, and Propionibacterium freudenreichii ssp. shermanii JS) to adhere alone or in different combinations to immobilized mucus. Probiotic combinations were clearly able to enhance the adhesion of L. rhamnosus GG, L. rhamnosus LC705, and P. freudenreichii ssp. shermanii JS. For L. rhamnosus GG and P. freudenreichii JS, all the combinations significantly improved adhesion to intestinal mucus, from 29.7 to 34.9% and from 1.9 to 2.3%, respectively. The adhesion of L. rhamnosus LC705 was improved from 0 to 46.4%. The adhesion of B. breve 99 was improved only in combination with L. rhamnosus GG and P. freudenreichii JS. Our results suggest that probiotic combinations could increase the beneficial health effects as compared with individual strains. Combinations of probiotic strains may therefore have synergistic adhesion effects, and such combinations also should be assessed in clinical studies.

Authors+Show Affiliations

Functional Foods Forum, University of Turku, Itäinen Pitkäkatu 4A, 20520 Turku, Finland. marcol@utu.fiNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17517710

Citation

Collado, M C., et al. "Development of New Probiotics By Strain Combinations: Is It Possible to Improve the Adhesion to Intestinal Mucus?" Journal of Dairy Science, vol. 90, no. 6, 2007, pp. 2710-6.
Collado MC, Meriluoto J, Salminen S. Development of new probiotics by strain combinations: is it possible to improve the adhesion to intestinal mucus? J Dairy Sci. 2007;90(6):2710-6.
Collado, M. C., Meriluoto, J., & Salminen, S. (2007). Development of new probiotics by strain combinations: is it possible to improve the adhesion to intestinal mucus? Journal of Dairy Science, 90(6), pp. 2710-6.
Collado MC, Meriluoto J, Salminen S. Development of New Probiotics By Strain Combinations: Is It Possible to Improve the Adhesion to Intestinal Mucus. J Dairy Sci. 2007;90(6):2710-6. PubMed PMID: 17517710.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Development of new probiotics by strain combinations: is it possible to improve the adhesion to intestinal mucus? AU - Collado,M C, AU - Meriluoto,J, AU - Salminen,S, PY - 2007/5/23/pubmed PY - 2007/8/10/medline PY - 2007/5/23/entrez SP - 2710 EP - 6 JF - Journal of dairy science JO - J. Dairy Sci. VL - 90 IS - 6 N2 - We evaluated the ability of commercial probiotic strains (Lactobacillus rhamnosus GG, L. rhamnosus LC705, Bifidobacterium breve 99, and Propionibacterium freudenreichii ssp. shermanii JS) to adhere alone or in different combinations to immobilized mucus. Probiotic combinations were clearly able to enhance the adhesion of L. rhamnosus GG, L. rhamnosus LC705, and P. freudenreichii ssp. shermanii JS. For L. rhamnosus GG and P. freudenreichii JS, all the combinations significantly improved adhesion to intestinal mucus, from 29.7 to 34.9% and from 1.9 to 2.3%, respectively. The adhesion of L. rhamnosus LC705 was improved from 0 to 46.4%. The adhesion of B. breve 99 was improved only in combination with L. rhamnosus GG and P. freudenreichii JS. Our results suggest that probiotic combinations could increase the beneficial health effects as compared with individual strains. Combinations of probiotic strains may therefore have synergistic adhesion effects, and such combinations also should be assessed in clinical studies. SN - 1525-3198 UR - https://www.unboundmedicine.com/medline/citation/17517710/Development_of_new_probiotics_by_strain_combinations:_is_it_possible_to_improve_the_adhesion_to_intestinal_mucus L2 - https://linkinghub.elsevier.com/retrieve/pii/S0022-0302(07)70081-4 DB - PRIME DP - Unbound Medicine ER -