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Texture anisotropy of the brain's white matter as revealed by anatomical MRI.

Abstract

The purpose of this work was to study specific texture properties of the brain's white matter (WM) based on conventional high-resolution T1-weighted magnetic resonance imaging (MRI) datasets. Quantitative parameters anisotropy and laminarity were derived from 3-D texture analysis. Differences in WM texture associated with gender were evaluated on an age-matched sample of 210 young healthy subjects (mean age 24.8, SD 3.97 years, 103 males and 107 females). Changes of WM texture with age were studied using 112 MRI-T1 datasets of healthy subjects aged 16 to 70 years (57 males and 55 females). Both texture measures indicated a "more regular" WM structure in females (p < 10(-6)). An age-related deterioration of WM structure manifests itself as a remarkable decline of both parameters (p < 10(-6)) that is more prominent in females (p < 10(-6)) than in males (p = 0.02). Texture analysis of anatomical MRI-T1 brain datasets provides quantitative information about macroscopic WM characteristics and helps discriminating between normal and pathological aging.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    United Institute of Informatics Problems, Belarus National Academy of Sciences, 220012 Minsk, Belarus. vassili.kovalev@gmail.com

    Source

    IEEE transactions on medical imaging 26:5 2007 May pg 678-85

    MeSH

    Adult
    Aging
    Algorithms
    Anisotropy
    Brain
    Female
    Humans
    Image Enhancement
    Image Interpretation, Computer-Assisted
    Imaging, Three-Dimensional
    Magnetic Resonance Imaging
    Male
    Nerve Fibers, Myelinated
    Reproducibility of Results
    Sensitivity and Specificity
    Sex Factors

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    17518062

    Citation

    Kovalev, Vassili, and Frithjof Kruggel. "Texture Anisotropy of the Brain's White Matter as Revealed By Anatomical MRI." IEEE Transactions On Medical Imaging, vol. 26, no. 5, 2007, pp. 678-85.
    Kovalev V, Kruggel F. Texture anisotropy of the brain's white matter as revealed by anatomical MRI. IEEE Trans Med Imaging. 2007;26(5):678-85.
    Kovalev, V., & Kruggel, F. (2007). Texture anisotropy of the brain's white matter as revealed by anatomical MRI. IEEE Transactions On Medical Imaging, 26(5), pp. 678-85.
    Kovalev V, Kruggel F. Texture Anisotropy of the Brain's White Matter as Revealed By Anatomical MRI. IEEE Trans Med Imaging. 2007;26(5):678-85. PubMed PMID: 17518062.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Texture anisotropy of the brain's white matter as revealed by anatomical MRI. AU - Kovalev,Vassili, AU - Kruggel,Frithjof, PY - 2007/5/24/pubmed PY - 2007/6/20/medline PY - 2007/5/24/entrez SP - 678 EP - 85 JF - IEEE transactions on medical imaging JO - IEEE Trans Med Imaging VL - 26 IS - 5 N2 - The purpose of this work was to study specific texture properties of the brain's white matter (WM) based on conventional high-resolution T1-weighted magnetic resonance imaging (MRI) datasets. Quantitative parameters anisotropy and laminarity were derived from 3-D texture analysis. Differences in WM texture associated with gender were evaluated on an age-matched sample of 210 young healthy subjects (mean age 24.8, SD 3.97 years, 103 males and 107 females). Changes of WM texture with age were studied using 112 MRI-T1 datasets of healthy subjects aged 16 to 70 years (57 males and 55 females). Both texture measures indicated a "more regular" WM structure in females (p < 10(-6)). An age-related deterioration of WM structure manifests itself as a remarkable decline of both parameters (p < 10(-6)) that is more prominent in females (p < 10(-6)) than in males (p = 0.02). Texture analysis of anatomical MRI-T1 brain datasets provides quantitative information about macroscopic WM characteristics and helps discriminating between normal and pathological aging. SN - 0278-0062 UR - https://www.unboundmedicine.com/medline/citation/17518062/Texture_anisotropy_of_the_brain's_white_matter_as_revealed_by_anatomical_MRI_ L2 - https://dx.doi.org/10.1109/TMI.2007.895481 DB - PRIME DP - Unbound Medicine ER -