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Temporary pancreatic stent to prevent post endoscopic retrograde cholangiopancreatography pancreatitis: a preliminary, single-center, randomized controlled trial.
J Hepatobiliary Pancreat Surg 2007; 14(3):302-7JH

Abstract

BACKGROUND

Post endoscopic retrograde cholangiopancreatography (post-ERCP) pancreatitis is the most common complication of ERCP, which can occasionally become serious or fatal. This preliminary study was to prospectively evaluate the efficacy of a temporary unflanged pancreatic duct stent (PS) to prevent post-ERCP pancreatitis.

METHODS

A total of 64 patients were randomly divided into a control group, which did not undergo stenting, and a stent group. The stent used was a 5-Fr pigtail PS without an inner flange.

RESULTS

Placement of an unflanged PS was successful and without complications in all 32 patients. The rates of hyperamylasemia were 50.0% and 34.4% in the control and stent groups, respectively (P > 0.05), and the mean serum amylase levels were 456.2 and 257.9 IU/l, respectively (P = 0.035). The overall rates of post-ERCP pancreatitis diagnosed according to Cotton's criteria were 12.5% and 3.1% in the control and stent groups, respectively (P > 0.05). The severity of pancreatitis was severe in one patient, moderate in one, and mild in two in the control group, whereas in the stent group, the single case of pancreatitis was mild.

CONCLUSIONS

Placement of an unflanged 5-Fr PS may be useful in preventing post-ERCP pancreatitis.

Authors+Show Affiliations

Division of Gastroenterology, Department of Internal Medicine, Tokyo Medical University, 6-7-1 Nishishinjuku, Tokyo 160-0023, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

17520207

Citation

Tsuchiya, Takayoshi, et al. "Temporary Pancreatic Stent to Prevent Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis: a Preliminary, Single-center, Randomized Controlled Trial." Journal of Hepato-biliary-pancreatic Surgery, vol. 14, no. 3, 2007, pp. 302-7.
Tsuchiya T, Itoi T, Sofuni A, et al. Temporary pancreatic stent to prevent post endoscopic retrograde cholangiopancreatography pancreatitis: a preliminary, single-center, randomized controlled trial. J Hepatobiliary Pancreat Surg. 2007;14(3):302-7.
Tsuchiya, T., Itoi, T., Sofuni, A., Itokawa, F., Kurihara, T., Ishii, K., ... Moriyasu, F. (2007). Temporary pancreatic stent to prevent post endoscopic retrograde cholangiopancreatography pancreatitis: a preliminary, single-center, randomized controlled trial. Journal of Hepato-biliary-pancreatic Surgery, 14(3), pp. 302-7.
Tsuchiya T, et al. Temporary Pancreatic Stent to Prevent Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis: a Preliminary, Single-center, Randomized Controlled Trial. J Hepatobiliary Pancreat Surg. 2007;14(3):302-7. PubMed PMID: 17520207.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Temporary pancreatic stent to prevent post endoscopic retrograde cholangiopancreatography pancreatitis: a preliminary, single-center, randomized controlled trial. AU - Tsuchiya,Takayoshi, AU - Itoi,Takao, AU - Sofuni,Atsushi, AU - Itokawa,Fumihide, AU - Kurihara,Toshio, AU - Ishii,Kentaro, AU - Tsuji,Syujiro, AU - Kawai,Takashi, AU - Moriyasu,Fuminori, Y1 - 2007/05/29/ PY - 2006/04/28/received PY - 2006/06/27/accepted PY - 2007/5/24/pubmed PY - 2007/12/7/medline PY - 2007/5/24/entrez SP - 302 EP - 7 JF - Journal of hepato-biliary-pancreatic surgery JO - J Hepatobiliary Pancreat Surg VL - 14 IS - 3 N2 - BACKGROUND: Post endoscopic retrograde cholangiopancreatography (post-ERCP) pancreatitis is the most common complication of ERCP, which can occasionally become serious or fatal. This preliminary study was to prospectively evaluate the efficacy of a temporary unflanged pancreatic duct stent (PS) to prevent post-ERCP pancreatitis. METHODS: A total of 64 patients were randomly divided into a control group, which did not undergo stenting, and a stent group. The stent used was a 5-Fr pigtail PS without an inner flange. RESULTS: Placement of an unflanged PS was successful and without complications in all 32 patients. The rates of hyperamylasemia were 50.0% and 34.4% in the control and stent groups, respectively (P > 0.05), and the mean serum amylase levels were 456.2 and 257.9 IU/l, respectively (P = 0.035). The overall rates of post-ERCP pancreatitis diagnosed according to Cotton's criteria were 12.5% and 3.1% in the control and stent groups, respectively (P > 0.05). The severity of pancreatitis was severe in one patient, moderate in one, and mild in two in the control group, whereas in the stent group, the single case of pancreatitis was mild. CONCLUSIONS: Placement of an unflanged 5-Fr PS may be useful in preventing post-ERCP pancreatitis. SN - 0944-1166 UR - https://www.unboundmedicine.com/medline/citation/17520207/Temporary_pancreatic_stent_to_prevent_post_endoscopic_retrograde_cholangiopancreatography_pancreatitis:_a_preliminary_single_center_randomized_controlled_trial_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0944-1166&date=2007&volume=14&issue=3&spage=302 DB - PRIME DP - Unbound Medicine ER -