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Clinical and instrumental study of the efficacy of a new sebum control cream.
J Cosmet Dermatol 2007; 6(2):113-8JC

Abstract

BACKGROUND

Some botanical compounds are considered useful to reduce sebum production. Aim To evaluate the efficacy of a sebum control cream containing polyphenol-rich extract from saw palmetto, sesame seeds, and argan oil in subjects with oily facial skin.

METHODS

The study was carried out during the winter months (January and February). A total of 20 healthy volunteers (9 male and 11 female, aged 17-50 years, 16 with oily skin and 4 with combined skin) were studied. The test product was applied twice daily to the face for a period of 4 weeks. A clinical assessment and instrumental measurements were done before and after the treatment period. Casual sebum level on the forehead and both cheeks was determined with a photometric device (Sebumeter). The quantity of sebum on the midforehead was determined using sebum collector foils (Sebufix), which were then evaluated with skin camera Visioscope and software SELS (Surface Evaluation of the Living Skin). A subjective evaluation questionnaire regarding the cosmetic characteristics, tolerance, and efficacy of the product was filled out by the volunteers at the end of study.

RESULTS

The product was very well accepted by all the volunteers. A visible sebum-regulating efficacy was reported in 95% of them. After 4 weeks of treatment, the clinical assessment scores decreased by 33%. There was a significant reduction in the casual sebum level by 20% and area covered with oily spots by 42%. The number of active sebaceous glands remained unaltered.

CONCLUSION

These results objectively and quantitatively show the efficacy of the sebum control cream tested to reduce the greasiness and improve the appearance of oily facial skin.

Authors+Show Affiliations

Department of Dermatology, Medical University, Plovdiv, Bulgaria. hristo_dobrev@hotmail.com

Pub Type(s)

Clinical Trial
Journal Article

Language

eng

PubMed ID

17524128

Citation

Dobrev, Hristo. "Clinical and Instrumental Study of the Efficacy of a New Sebum Control Cream." Journal of Cosmetic Dermatology, vol. 6, no. 2, 2007, pp. 113-8.
Dobrev H. Clinical and instrumental study of the efficacy of a new sebum control cream. J Cosmet Dermatol. 2007;6(2):113-8.
Dobrev, H. (2007). Clinical and instrumental study of the efficacy of a new sebum control cream. Journal of Cosmetic Dermatology, 6(2), pp. 113-8.
Dobrev H. Clinical and Instrumental Study of the Efficacy of a New Sebum Control Cream. J Cosmet Dermatol. 2007;6(2):113-8. PubMed PMID: 17524128.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical and instrumental study of the efficacy of a new sebum control cream. A1 - Dobrev,Hristo, PY - 2007/5/26/pubmed PY - 2008/3/26/medline PY - 2007/5/26/entrez SP - 113 EP - 8 JF - Journal of cosmetic dermatology JO - J Cosmet Dermatol VL - 6 IS - 2 N2 - BACKGROUND: Some botanical compounds are considered useful to reduce sebum production. Aim To evaluate the efficacy of a sebum control cream containing polyphenol-rich extract from saw palmetto, sesame seeds, and argan oil in subjects with oily facial skin. METHODS: The study was carried out during the winter months (January and February). A total of 20 healthy volunteers (9 male and 11 female, aged 17-50 years, 16 with oily skin and 4 with combined skin) were studied. The test product was applied twice daily to the face for a period of 4 weeks. A clinical assessment and instrumental measurements were done before and after the treatment period. Casual sebum level on the forehead and both cheeks was determined with a photometric device (Sebumeter). The quantity of sebum on the midforehead was determined using sebum collector foils (Sebufix), which were then evaluated with skin camera Visioscope and software SELS (Surface Evaluation of the Living Skin). A subjective evaluation questionnaire regarding the cosmetic characteristics, tolerance, and efficacy of the product was filled out by the volunteers at the end of study. RESULTS: The product was very well accepted by all the volunteers. A visible sebum-regulating efficacy was reported in 95% of them. After 4 weeks of treatment, the clinical assessment scores decreased by 33%. There was a significant reduction in the casual sebum level by 20% and area covered with oily spots by 42%. The number of active sebaceous glands remained unaltered. CONCLUSION: These results objectively and quantitatively show the efficacy of the sebum control cream tested to reduce the greasiness and improve the appearance of oily facial skin. SN - 1473-2165 UR - https://www.unboundmedicine.com/medline/citation/17524128/Clinical_and_instrumental_study_of_the_efficacy_of_a_new_sebum_control_cream_ L2 - https://doi.org/10.1111/j.1473-2165.2007.00306.x DB - PRIME DP - Unbound Medicine ER -