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Resting energy expenditure in children with neonatal chronic lung disease and obstruction of the airways.

Abstract

Children with history of broncho-pulmonary dysplasia (BPD) often suffer from growth failure and lung sequelae. The main objective of this study was to test the role of pulmonary obstruction on resting energy expenditure (REE) and nutritional status in BPD. Seventy-one children with BPD (34 boys and 37 girls) and 30 controls (20 boys and 10 girls) aged 4-8 years were enrolled. Body composition was assessed by bio-impedancemetry measurements; REE was measured by indirect calorimetry. Predicted REE was calculated using the Schofield equation. The population of children with BPD was divided into three groups: children without obstruction of the airways, children with moderate obstruction of the airways, and children with severe obstruction. Children with BPD were significantly smaller and leaner than controls. Altered body composition (reduction of fat mass) was observed in BPD children that suffered from airway obstruction. REE was significantly lower in children with BPD compared to controls, but when adjusted for weight and fat-free mass no significant difference was observed irrespective of pulmonary status. Airway obstruction in children with BPD does not appear to be associated with an increased REE. Moreover altered REE could not explain the altered nutritional status that is still observed in BPD in later childhood. This supports the hypothesis that body composition and pulmonary function in BPD in later childhood are fixed sequelae originating from the neonatal period.

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  • Authors+Show Affiliations

    ,

    EA 3925, IFR 114, Université de Lille 2, Clinique de Pédiatrie, Hôpital Jeanne de Flandre, Lille, France.

    , , , ,

    Source

    The British journal of nutrition 98:4 2007 Oct pg 796-801

    MeSH

    Body Composition
    Bronchopulmonary Dysplasia
    Child
    Child, Preschool
    Electric Impedance
    Energy Metabolism
    Female
    Humans
    Hyaline Membrane Disease
    Infant, Newborn
    Male
    Nutritional Status
    Predictive Value of Tests
    Pulmonary Disease, Chronic Obstructive

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    17524179

    Citation

    Bott, Lucile, et al. "Resting Energy Expenditure in Children With Neonatal Chronic Lung Disease and Obstruction of the Airways." The British Journal of Nutrition, vol. 98, no. 4, 2007, pp. 796-801.
    Bott L, Béghin L, Hankard R, et al. Resting energy expenditure in children with neonatal chronic lung disease and obstruction of the airways. Br J Nutr. 2007;98(4):796-801.
    Bott, L., Béghin, L., Hankard, R., Pierrat, V., Gondon, E., & Gottrand, F. (2007). Resting energy expenditure in children with neonatal chronic lung disease and obstruction of the airways. The British Journal of Nutrition, 98(4), pp. 796-801.
    Bott L, et al. Resting Energy Expenditure in Children With Neonatal Chronic Lung Disease and Obstruction of the Airways. Br J Nutr. 2007;98(4):796-801. PubMed PMID: 17524179.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Resting energy expenditure in children with neonatal chronic lung disease and obstruction of the airways. AU - Bott,Lucile, AU - Béghin,Laurent, AU - Hankard,Régis, AU - Pierrat,Véronique, AU - Gondon,Emmanuelle, AU - Gottrand,Frédéric, Y1 - 2007/05/25/ PY - 2007/5/26/pubmed PY - 2008/2/12/medline PY - 2007/5/26/entrez SP - 796 EP - 801 JF - The British journal of nutrition JO - Br. J. Nutr. VL - 98 IS - 4 N2 - Children with history of broncho-pulmonary dysplasia (BPD) often suffer from growth failure and lung sequelae. The main objective of this study was to test the role of pulmonary obstruction on resting energy expenditure (REE) and nutritional status in BPD. Seventy-one children with BPD (34 boys and 37 girls) and 30 controls (20 boys and 10 girls) aged 4-8 years were enrolled. Body composition was assessed by bio-impedancemetry measurements; REE was measured by indirect calorimetry. Predicted REE was calculated using the Schofield equation. The population of children with BPD was divided into three groups: children without obstruction of the airways, children with moderate obstruction of the airways, and children with severe obstruction. Children with BPD were significantly smaller and leaner than controls. Altered body composition (reduction of fat mass) was observed in BPD children that suffered from airway obstruction. REE was significantly lower in children with BPD compared to controls, but when adjusted for weight and fat-free mass no significant difference was observed irrespective of pulmonary status. Airway obstruction in children with BPD does not appear to be associated with an increased REE. Moreover altered REE could not explain the altered nutritional status that is still observed in BPD in later childhood. This supports the hypothesis that body composition and pulmonary function in BPD in later childhood are fixed sequelae originating from the neonatal period. SN - 0007-1145 UR - https://www.unboundmedicine.com/medline/citation/17524179/Resting_energy_expenditure_in_children_with_neonatal_chronic_lung_disease_and_obstruction_of_the_airways_ L2 - https://www.cambridge.org/core/product/identifier/S0007114507744392/type/journal_article DB - PRIME DP - Unbound Medicine ER -