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Sudden death due to central alveolar hypoventilation syndrome (Ondine's curse) in a 39-year-old woman with heterotopia of the inferior olive.
Am J Forensic Med Pathol. 2007 Jun; 28(2):141-4.AJ

Abstract

Failure of automatic involuntary respiration with preservation of voluntary respiratory drive (Ondine's curse) is a rare occurrence which has been reported following a variety of morphologic lesions near respiratory centers in the lower brainstem. We report the case of a 39-year-old woman with a syndrome of fulminant respiratory failure with features of Ondine's curse in whom neuropathologic examination disclosed a preexisting malformation of the lower brainstem, as well as acute local subarachnoid bleeding. Mechanisms in the present case are discussed and a review of similar cases published so far is given. The necessity of sound investigation, including neuropathologic studies in cases of sudden unexplained death, is underlined.

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Authors+Show Affiliations

Matschke J
Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. matschke@uke.uni-hamburg.de
Laas R
No affiliation info available

MeSH

AdultBrain StemDeath, SuddenFemaleHumansShockSleep Apnea, CentralSubarachnoid Hemorrhage

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

17525565

Citation

Matschke, Jakob, and Rudolf Laas. "Sudden Death Due to Central Alveolar Hypoventilation Syndrome (Ondine's Curse) in a 39-year-old Woman With Heterotopia of the Inferior Olive." The American Journal of Forensic Medicine and Pathology, vol. 28, no. 2, 2007, pp. 141-4.
Matschke J, Laas R. Sudden death due to central alveolar hypoventilation syndrome (Ondine's curse) in a 39-year-old woman with heterotopia of the inferior olive. Am J Forensic Med Pathol. 2007;28(2):141-4.
Matschke, J., & Laas, R. (2007). Sudden death due to central alveolar hypoventilation syndrome (Ondine's curse) in a 39-year-old woman with heterotopia of the inferior olive. The American Journal of Forensic Medicine and Pathology, 28(2), 141-4.
Matschke J, Laas R. Sudden Death Due to Central Alveolar Hypoventilation Syndrome (Ondine's Curse) in a 39-year-old Woman With Heterotopia of the Inferior Olive. Am J Forensic Med Pathol. 2007;28(2):141-4. PubMed PMID: 17525565.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sudden death due to central alveolar hypoventilation syndrome (Ondine's curse) in a 39-year-old woman with heterotopia of the inferior olive. AU - Matschke,Jakob, AU - Laas,Rudolf, PY - 2007/5/26/pubmed PY - 2007/9/19/medline PY - 2007/5/26/entrez SP - 141 EP - 4 JF - The American journal of forensic medicine and pathology JO - Am J Forensic Med Pathol VL - 28 IS - 2 N2 - Failure of automatic involuntary respiration with preservation of voluntary respiratory drive (Ondine's curse) is a rare occurrence which has been reported following a variety of morphologic lesions near respiratory centers in the lower brainstem. We report the case of a 39-year-old woman with a syndrome of fulminant respiratory failure with features of Ondine's curse in whom neuropathologic examination disclosed a preexisting malformation of the lower brainstem, as well as acute local subarachnoid bleeding. Mechanisms in the present case are discussed and a review of similar cases published so far is given. The necessity of sound investigation, including neuropathologic studies in cases of sudden unexplained death, is underlined. SN - 0195-7910 UR - https://www.unboundmedicine.com/medline/citation/17525565/Sudden_death_due_to_central_alveolar_hypoventilation_syndrome__Ondine's_curse__in_a_39_year_old_woman_with_heterotopia_of_the_inferior_olive_ L2 - https://doi.org/10.1097/01.paf.0000257396.79742.e9 DB - PRIME DP - Unbound Medicine ER -