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Comparison of blood lead levels of mothers and cord blood in intrauterine growth retarded neonates and normal term neonates.
Saudi Med J. 2007 Jun; 28(6):877-80.SM

Abstract

OBJECTIVE

To compare the blood lead levels of mothers and cord blood in intrauterine growth retarded (IUGR) neonates and normal term neonates.

METHODS

From April to December 2005, we carried out a cross-sectional, prospective study in Isfahan University of Medical Sciences, Isfahan, Iran. Blood lead levels were measured in the umbilical cord and maternal venous blood samples in 32 mother-infant pairs with IUGR full term neonates, and 34 mother-infant pairs with normal full term neonates. Blood-lead levels were analyzed by atomic absorption spectrometry.

RESULTS

The mean lead concentration in neonates of IUGR and normal groups was not significantly different (107.47 +/- 16.75 versus 113.08 +/- 19.08 micrometer/L, p=0.2). The mean lead concentration in mothers of IUGR group was lower than normal groups, but this difference was not significant (124.56 +/- 19.71 versus 135.26 +/- 26.91 micrometer/L, p=0.07). Maternal lead levels were strongly related with cord blood in both IUGR and normal groups (r=0.8, p<0.0001). Maternal and cord blood lead levels was not correlated with birth weight of newborns in either group. Overall, 65.6% of IUGR neonates and 76.4% of normal neonates was above the critical level defined for lead poisoning as >100 micrometer/L by the centers for disease control; however, this was not statistically different between the groups.

CONCLUSION

Our results indicate that the mean lead level was not higher in IUGR neonates, and the whole blood lead was not related to the birth weight. In addition, maternal and cord blood lead levels were strongly correlated, and there were remarkable lead burdens on both the mothers and their neonates in this industrial area.

Authors+Show Affiliations

Department of Pediatrics, Division of Neonatology, Al-Zahra Hospital, Sofe Bolvar, Isfahan 8174675731, Iran. iranpour@med.mui.ac.irNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

17530103

Citation

Iranpour, Ramin, et al. "Comparison of Blood Lead Levels of Mothers and Cord Blood in Intrauterine Growth Retarded Neonates and Normal Term Neonates." Saudi Medical Journal, vol. 28, no. 6, 2007, pp. 877-80.
Iranpour R, Besharati AA, Nasseri F, et al. Comparison of blood lead levels of mothers and cord blood in intrauterine growth retarded neonates and normal term neonates. Saudi Med J. 2007;28(6):877-80.
Iranpour, R., Besharati, A. A., Nasseri, F., Hashemipour, M., Balali-Mood, M., & Kelishadi, R. (2007). Comparison of blood lead levels of mothers and cord blood in intrauterine growth retarded neonates and normal term neonates. Saudi Medical Journal, 28(6), 877-80.
Iranpour R, et al. Comparison of Blood Lead Levels of Mothers and Cord Blood in Intrauterine Growth Retarded Neonates and Normal Term Neonates. Saudi Med J. 2007;28(6):877-80. PubMed PMID: 17530103.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of blood lead levels of mothers and cord blood in intrauterine growth retarded neonates and normal term neonates. AU - Iranpour,Ramin, AU - Besharati,Amir A, AU - Nasseri,Fatemeh, AU - Hashemipour,Mahin, AU - Balali-Mood,Mahdi, AU - Kelishadi,Roya, PY - 2007/5/29/pubmed PY - 2007/7/28/medline PY - 2007/5/29/entrez SP - 877 EP - 80 JF - Saudi medical journal JO - Saudi Med J VL - 28 IS - 6 N2 - OBJECTIVE: To compare the blood lead levels of mothers and cord blood in intrauterine growth retarded (IUGR) neonates and normal term neonates. METHODS: From April to December 2005, we carried out a cross-sectional, prospective study in Isfahan University of Medical Sciences, Isfahan, Iran. Blood lead levels were measured in the umbilical cord and maternal venous blood samples in 32 mother-infant pairs with IUGR full term neonates, and 34 mother-infant pairs with normal full term neonates. Blood-lead levels were analyzed by atomic absorption spectrometry. RESULTS: The mean lead concentration in neonates of IUGR and normal groups was not significantly different (107.47 +/- 16.75 versus 113.08 +/- 19.08 micrometer/L, p=0.2). The mean lead concentration in mothers of IUGR group was lower than normal groups, but this difference was not significant (124.56 +/- 19.71 versus 135.26 +/- 26.91 micrometer/L, p=0.07). Maternal lead levels were strongly related with cord blood in both IUGR and normal groups (r=0.8, p<0.0001). Maternal and cord blood lead levels was not correlated with birth weight of newborns in either group. Overall, 65.6% of IUGR neonates and 76.4% of normal neonates was above the critical level defined for lead poisoning as >100 micrometer/L by the centers for disease control; however, this was not statistically different between the groups. CONCLUSION: Our results indicate that the mean lead level was not higher in IUGR neonates, and the whole blood lead was not related to the birth weight. In addition, maternal and cord blood lead levels were strongly correlated, and there were remarkable lead burdens on both the mothers and their neonates in this industrial area. SN - 0379-5284 UR - https://www.unboundmedicine.com/medline/citation/17530103/Comparison_of_blood_lead_levels_of_mothers_and_cord_blood_in_intrauterine_growth_retarded_neonates_and_normal_term_neonates_ DB - PRIME DP - Unbound Medicine ER -