TY - JOUR T1 - Determining enediol compounds in tea using surface-assisted laser desorption/ionization mass spectrometry with titanium dioxide nanoparticle matrices. AU - Lee,Kun-Hong, AU - Chiang,Cheng-Kang, AU - Lin,Zong-Hong, AU - Chang,Huan-Tsung, PY - 2007/5/31/pubmed PY - 2007/5/31/medline PY - 2007/5/31/entrez SP - 2023 EP - 30 JF - Rapid communications in mass spectrometry : RCM JO - Rapid Commun Mass Spectrom VL - 21 IS - 13 N2 - We describe the use of titanium dioxide nanoparticles (TiO2 NPs) as selective probes and matrices for the determination of catechins using surface-assisted laser desorption/ionization mass spectrometry (SALDI-MS). The interactions between the enediol compounds and TiO2 NPs were evident by the change in color of the TiO2 NP solution from milky white to orange. Through these interactions, the TiO2 NPs could be used to concentrate enediol compounds, including catechins and ascorbic acid. The limits of detection (LODs) for three catechins--catechin, (-)-epigallocatechin, and (-)-epigallocatechin gallate--at a signal-to-noise ratio of 3 were 0.45, 1.85 and 0.65 microM, respectively. The TiO2 NP matrices provide a number of advantages over conventional organic matrices (e.g. 2',4',6'-trihydroxyacetophenone), including ease of sample preparation, less background noise in the low-mass region, and high repeatability. The applicability of this method was confirmed through the high reproducibility of the determination of the two catechins in tea samples that had not been subjected to any sample preparation procedures (shot-to-shot variation: <10%). SN - 0951-4198 UR - https://www.unboundmedicine.com/medline/citation/17534856/Determining_enediol_compounds_in_tea_using_surface_assisted_laser_desorption/ionization_mass_spectrometry_with_titanium_dioxide_nanoparticle_matrices_ L2 - https://doi.org/10.1002/rcm.3058 DB - PRIME DP - Unbound Medicine ER -