Tags

Type your tag names separated by a space and hit enter

Retroperitoneal extramedullary anaplastic plasmacytoma masquerading as sarcoma: Report of a case with an unusual presentation and imprint smears.
Acta Cytol. 2007 May-Jun; 51(3):434-6.AC

Abstract

BACKGROUND

Extramedullary plasmacytoma of the retroperitoneum is rare. Furthermore, plasmacytoma with anaplastic features can be confused with high grade sarcoma clinically and histologically, particularly when the initial immunohistochemical tumor markers are negative. However, paying attention to cytologic imprint smears can give valuable clues to the correct diagnosis.

CASE

A 73-year-old male was admitted to our hospital with a recent history of back pain. Abdominal computed tomography revealed a large retroperitoneal mass (6.8 x 5.1 cm). The initial pathologic evaluation revealed a high grade pleomorphic neoplasm that failed to express multiple epithelial, mesenchymal, lymphoid and melanoma immunohistochemical markers. Subsequent fresh tissue evaluation with touch imprints and immunophenotypic characterization confirmed the plasma cell origin of the tumor. Thorough retrospective review of the touch imprint smears clearly showed the plasmacytic cytologic features. Features of multiple myeloma were essentially absent.

CONCLUSION

Performing cytologic imprint smears on fresh tissue material may help in making the correct diagnosis and is highly recommended.

Authors+Show Affiliations

Department of Pathology and Internal Medicine, Harper University Hospital, Wayne State University, Detroit, Michigan, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

17536549

Citation

Khayyata, Said, et al. "Retroperitoneal Extramedullary Anaplastic Plasmacytoma Masquerading as Sarcoma: Report of a Case With an Unusual Presentation and Imprint Smears." Acta Cytologica, vol. 51, no. 3, 2007, pp. 434-6.
Khayyata S, Bentley G, Fregene TA, et al. Retroperitoneal extramedullary anaplastic plasmacytoma masquerading as sarcoma: Report of a case with an unusual presentation and imprint smears. Acta Cytol. 2007;51(3):434-6.
Khayyata, S., Bentley, G., Fregene, T. A., & Al-Abbadi, M. (2007). Retroperitoneal extramedullary anaplastic plasmacytoma masquerading as sarcoma: Report of a case with an unusual presentation and imprint smears. Acta Cytologica, 51(3), 434-6.
Khayyata S, et al. Retroperitoneal Extramedullary Anaplastic Plasmacytoma Masquerading as Sarcoma: Report of a Case With an Unusual Presentation and Imprint Smears. Acta Cytol. 2007 May-Jun;51(3):434-6. PubMed PMID: 17536549.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Retroperitoneal extramedullary anaplastic plasmacytoma masquerading as sarcoma: Report of a case with an unusual presentation and imprint smears. AU - Khayyata,Said, AU - Bentley,Gail, AU - Fregene,Tosan A, AU - Al-Abbadi,Mousa, PY - 2007/6/1/pubmed PY - 2007/6/28/medline PY - 2007/6/1/entrez SP - 434 EP - 6 JF - Acta cytologica JO - Acta Cytol. VL - 51 IS - 3 N2 - BACKGROUND: Extramedullary plasmacytoma of the retroperitoneum is rare. Furthermore, plasmacytoma with anaplastic features can be confused with high grade sarcoma clinically and histologically, particularly when the initial immunohistochemical tumor markers are negative. However, paying attention to cytologic imprint smears can give valuable clues to the correct diagnosis. CASE: A 73-year-old male was admitted to our hospital with a recent history of back pain. Abdominal computed tomography revealed a large retroperitoneal mass (6.8 x 5.1 cm). The initial pathologic evaluation revealed a high grade pleomorphic neoplasm that failed to express multiple epithelial, mesenchymal, lymphoid and melanoma immunohistochemical markers. Subsequent fresh tissue evaluation with touch imprints and immunophenotypic characterization confirmed the plasma cell origin of the tumor. Thorough retrospective review of the touch imprint smears clearly showed the plasmacytic cytologic features. Features of multiple myeloma were essentially absent. CONCLUSION: Performing cytologic imprint smears on fresh tissue material may help in making the correct diagnosis and is highly recommended. SN - 0001-5547 UR - https://www.unboundmedicine.com/medline/citation/17536549/Retroperitoneal_extramedullary_anaplastic_plasmacytoma_masquerading_as_sarcoma:_Report_of_a_case_with_an_unusual_presentation_and_imprint_smears_ L2 - https://www.karger.com?DOI=10.1159/000325761 DB - PRIME DP - Unbound Medicine ER -