Oriented cell divisions and muscle satellite cell heterogeneity.Cell. 2007 Jun 01; 129(5):859-61.Cell
Satellite cells are crucial for maintaining muscle homeostasis and for regeneration following injury. In this issue, Kuang et al. (2007) reveal that muscle satellite cells are a heterogeneous mixture of stem cells and committed myogenic progenitors. They show that asymmetric division of stem cells in the satellite cell niche is a mechanism for generating these two populations.