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Epidemiology and natural history of NAFLD and NASH.
Clin Liver Dis. 2007 Feb; 11(1):1-16, vii.CL

Abstract

Understanding of the epidemiology and natural history of non-alcoholic fatty liver disease (NAFLD) has increased; it is the most common form of chronic liver disease in the Western world and increasing in importance in other parts of the world. Prevalence is expected to increase as obesity and diabetes epidemics evolve. The natural history of NAFLD depends on the histologic subtype. Those who have simple hepatic steatosis or nonspecific inflammation generally have a benign long-term prognosis, whereas non-alcoholic steatohepatitis (NASH) can progress to cirrhosis. NASH-related cirrhosis may have a similar prognosis as cirrhosis from other causes, leading to liver failure or hepatocellular carcinoma.

Authors+Show Affiliations

Center for Liver Diseases, Inova Fairfax Hospital, 3289 Woodburn Road, Annadale, VA 22003, USA.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

17544968

Citation

Ong, Janus P., and Zobair M. Younossi. "Epidemiology and Natural History of NAFLD and NASH." Clinics in Liver Disease, vol. 11, no. 1, 2007, pp. 1-16, vii.
Ong JP, Younossi ZM. Epidemiology and natural history of NAFLD and NASH. Clin Liver Dis. 2007;11(1):1-16, vii.
Ong, J. P., & Younossi, Z. M. (2007). Epidemiology and natural history of NAFLD and NASH. Clinics in Liver Disease, 11(1), 1-16, vii.
Ong JP, Younossi ZM. Epidemiology and Natural History of NAFLD and NASH. Clin Liver Dis. 2007;11(1):1-16, vii. PubMed PMID: 17544968.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Epidemiology and natural history of NAFLD and NASH. AU - Ong,Janus P, AU - Younossi,Zobair M, PY - 2007/6/5/pubmed PY - 2007/10/6/medline PY - 2007/6/5/entrez SP - 1-16, vii JF - Clinics in liver disease JO - Clin Liver Dis VL - 11 IS - 1 N2 - Understanding of the epidemiology and natural history of non-alcoholic fatty liver disease (NAFLD) has increased; it is the most common form of chronic liver disease in the Western world and increasing in importance in other parts of the world. Prevalence is expected to increase as obesity and diabetes epidemics evolve. The natural history of NAFLD depends on the histologic subtype. Those who have simple hepatic steatosis or nonspecific inflammation generally have a benign long-term prognosis, whereas non-alcoholic steatohepatitis (NASH) can progress to cirrhosis. NASH-related cirrhosis may have a similar prognosis as cirrhosis from other causes, leading to liver failure or hepatocellular carcinoma. SN - 1089-3261 UR - https://www.unboundmedicine.com/medline/citation/17544968/Epidemiology_and_natural_history_of_NAFLD_and_NASH_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1089-3261(07)00010-4 DB - PRIME DP - Unbound Medicine ER -
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