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Nutrition in inflammatory bowel disease.

Abstract

PURPOSE OF REVIEW

Nutrition plays a significant role in the pathogenesis and treatment of the two major forms of inflammatory bowel disease: Crohn's disease and ulcerative colitis. In addition, patients with inflammatory bowel disease are often found to have nutrient deficiencies at the time of diagnosis, whereas others develop features of malnutrition over the course of their illness. Therefore, an understanding of the relationship between nutrients and inflammatory bowel disease is important if these patients are to receive optimal care.

RECENT FINDINGS

Epidemiologic and basic research has helped to shed light on the interaction between diet and the pathogenesis of inflammatory bowel disease. Numerous clinical trials utilizing various types of lipids, including fish oil and short chain fatty acids, suggest that fats play an important role in the inflammatory response that characterizes inflammatory bowel disease. Vitamins and other micronutrients involved in nutrient metabolism and modulation of oxidative stress are also considered in this review.

SUMMARY

This update discusses nutritional issues that can be used to help prevent and treat nutrient deficiencies and ameliorate disease activity in individuals with inflammatory bowel disease.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Northeastern Ohio Universities College of Medicine, Rootstown, OH, USA.

    Source

    MeSH

    Animals
    Antioxidants
    Diet
    Dietary Fats
    Dietary Fiber
    Dietary Supplements
    Fish Oils
    Humans
    Inflammatory Bowel Diseases
    Malnutrition
    Nutritional Status
    Nutritional Support

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    17545776

    Citation

    Razack, Razvi, and Douglas L. Seidner. "Nutrition in Inflammatory Bowel Disease." Current Opinion in Gastroenterology, vol. 23, no. 4, 2007, pp. 400-5.
    Razack R, Seidner DL. Nutrition in inflammatory bowel disease. Curr Opin Gastroenterol. 2007;23(4):400-5.
    Razack, R., & Seidner, D. L. (2007). Nutrition in inflammatory bowel disease. Current Opinion in Gastroenterology, 23(4), pp. 400-5.
    Razack R, Seidner DL. Nutrition in Inflammatory Bowel Disease. Curr Opin Gastroenterol. 2007;23(4):400-5. PubMed PMID: 17545776.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Nutrition in inflammatory bowel disease. AU - Razack,Razvi, AU - Seidner,Douglas L, PY - 2007/6/5/pubmed PY - 2007/9/19/medline PY - 2007/6/5/entrez SP - 400 EP - 5 JF - Current opinion in gastroenterology JO - Curr. Opin. Gastroenterol. VL - 23 IS - 4 N2 - PURPOSE OF REVIEW: Nutrition plays a significant role in the pathogenesis and treatment of the two major forms of inflammatory bowel disease: Crohn's disease and ulcerative colitis. In addition, patients with inflammatory bowel disease are often found to have nutrient deficiencies at the time of diagnosis, whereas others develop features of malnutrition over the course of their illness. Therefore, an understanding of the relationship between nutrients and inflammatory bowel disease is important if these patients are to receive optimal care. RECENT FINDINGS: Epidemiologic and basic research has helped to shed light on the interaction between diet and the pathogenesis of inflammatory bowel disease. Numerous clinical trials utilizing various types of lipids, including fish oil and short chain fatty acids, suggest that fats play an important role in the inflammatory response that characterizes inflammatory bowel disease. Vitamins and other micronutrients involved in nutrient metabolism and modulation of oxidative stress are also considered in this review. SUMMARY: This update discusses nutritional issues that can be used to help prevent and treat nutrient deficiencies and ameliorate disease activity in individuals with inflammatory bowel disease. SN - 0267-1379 UR - https://www.unboundmedicine.com/medline/citation/17545776/Nutrition_in_inflammatory_bowel_disease_ L2 - http://Insights.ovid.com/pubmed?pmid=17545776 DB - PRIME DP - Unbound Medicine ER -