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The epidemiology of the dementias: an update.

Abstract

PURPOSE OF REVIEW

The epidemiology of dementia is one of the priority fields in aging research. This review aims to highlight the most relevant findings over last years concerning occurrence, risk factors, and prevention of dementia and its major subtypes.

RECENT FINDINGS

It is estimated that currently around 24 million people have dementia in the world, with the number being projected to double every 20 years, and that 60% of dementia patients live in developing countries, with the proportion being raised to more than 70% by 2040. Current evidence suggests that vascular factors, such as midlife hypertension, diabetes, and cerebrovascular disease, contribute significantly to the development of dementia and Alzheimer's disease, and that active engagement in mental, physical, and social activities may postpone the onset of dementia by providing cognitive reserve.

SUMMARY

Dementia represents a major public health challenge as a consequence of rapid increase in the aging population worldwide, especially in developing countries. This challenge can be partly confronted by successful development of preventive strategies. Evidence has emerged that proper control of vascular disorders and maintenance of active lifestyles may prevent or delay the onset and progression of dementia and Alzheimer's disease. Intervention trials are warranted to determine, to what extent, such programs are effective against dementia.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Aging Research Center, Department of Neurobiology, Caring Sciences and Society (NVS), Karolinska Institutet and the Stockholm Gerontology Research Center, Stockholm, Sweden. chengxuan.qiu@ki.se

    ,

    Source

    Current opinion in psychiatry 20:4 2007 Jul pg 380-5

    MeSH

    Aged
    Aged, 80 and over
    Alcoholism
    Alzheimer Disease
    C-Reactive Protein
    Cerebrovascular Disorders
    Cognition Disorders
    Coronary Disease
    Dementia
    Diabetes Mellitus
    Humans
    Hyperlipidemias
    Hypertension
    Life Style
    Middle Aged
    Nutritional Status
    Obesity
    Prevalence
    Psychology
    Risk Factors
    Smoking
    Social Support

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't
    Review

    Language

    eng

    PubMed ID

    17551353

    Citation

    Qiu, Chengxuan, et al. "The Epidemiology of the Dementias: an Update." Current Opinion in Psychiatry, vol. 20, no. 4, 2007, pp. 380-5.
    Qiu C, De Ronchi D, Fratiglioni L. The epidemiology of the dementias: an update. Curr Opin Psychiatry. 2007;20(4):380-5.
    Qiu, C., De Ronchi, D., & Fratiglioni, L. (2007). The epidemiology of the dementias: an update. Current Opinion in Psychiatry, 20(4), pp. 380-5.
    Qiu C, De Ronchi D, Fratiglioni L. The Epidemiology of the Dementias: an Update. Curr Opin Psychiatry. 2007;20(4):380-5. PubMed PMID: 17551353.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - The epidemiology of the dementias: an update. AU - Qiu,Chengxuan, AU - De Ronchi,Diana, AU - Fratiglioni,Laura, PY - 2007/6/7/pubmed PY - 2007/9/6/medline PY - 2007/6/7/entrez SP - 380 EP - 5 JF - Current opinion in psychiatry JO - Curr Opin Psychiatry VL - 20 IS - 4 N2 - PURPOSE OF REVIEW: The epidemiology of dementia is one of the priority fields in aging research. This review aims to highlight the most relevant findings over last years concerning occurrence, risk factors, and prevention of dementia and its major subtypes. RECENT FINDINGS: It is estimated that currently around 24 million people have dementia in the world, with the number being projected to double every 20 years, and that 60% of dementia patients live in developing countries, with the proportion being raised to more than 70% by 2040. Current evidence suggests that vascular factors, such as midlife hypertension, diabetes, and cerebrovascular disease, contribute significantly to the development of dementia and Alzheimer's disease, and that active engagement in mental, physical, and social activities may postpone the onset of dementia by providing cognitive reserve. SUMMARY: Dementia represents a major public health challenge as a consequence of rapid increase in the aging population worldwide, especially in developing countries. This challenge can be partly confronted by successful development of preventive strategies. Evidence has emerged that proper control of vascular disorders and maintenance of active lifestyles may prevent or delay the onset and progression of dementia and Alzheimer's disease. Intervention trials are warranted to determine, to what extent, such programs are effective against dementia. SN - 0951-7367 UR - https://www.unboundmedicine.com/medline/citation/17551353/The_epidemiology_of_the_dementias:_an_update_ L2 - http://Insights.ovid.com/pubmed?pmid=17551353 DB - PRIME DP - Unbound Medicine ER -