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Acute respiratory distress syndrome in scrub typhus.
Am J Trop Med Hyg. 2007 Jun; 76(6):1148-52.AJ

Abstract

Scrub typhus is a mite-borne infectious disease caused by Orientia tsutsugamushi. Acute respiratory distress syndrome (ARDS) is a serious complication of scrub typhus. This study retrospectively reviewed the medical records of 72 patients diagnosed with scrub typhus from January 1998 to August 2006 in Kaohsiung Chang Gung Memorial Hospital in Taiwan. Eight of 72 scrub typhus patients with ARDS were included in the study; the other patients without ARDS were used as controls. The mortality rate for the scrub typhus patients with ARDS was 25%. The eight patients seldom had underlying diseases. Initial presentations of dyspnea and cough, white blood cell count, hematocrit, total bilirubin, and delayed used of appropriate antibiotics use were significant predictors of ARDS. Multivariate analysis showed that albumin, prothrombin time, and delayed use of appropriate antibiotics were independent predictors of ARDS. Identification of these relative risk factors may help clinicians evaluate clinical cases of scrub typhus with ARDS.

Authors+Show Affiliations

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan, Republic of China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17556627

Citation

Wang, Chin-Chou, et al. "Acute Respiratory Distress Syndrome in Scrub Typhus." The American Journal of Tropical Medicine and Hygiene, vol. 76, no. 6, 2007, pp. 1148-52.
Wang CC, Liu SF, Liu JW, et al. Acute respiratory distress syndrome in scrub typhus. Am J Trop Med Hyg. 2007;76(6):1148-52.
Wang, C. C., Liu, S. F., Liu, J. W., Chung, Y. H., Su, M. C., & Lin, M. C. (2007). Acute respiratory distress syndrome in scrub typhus. The American Journal of Tropical Medicine and Hygiene, 76(6), 1148-52.
Wang CC, et al. Acute Respiratory Distress Syndrome in Scrub Typhus. Am J Trop Med Hyg. 2007;76(6):1148-52. PubMed PMID: 17556627.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acute respiratory distress syndrome in scrub typhus. AU - Wang,Chin-Chou, AU - Liu,Shih-Feng, AU - Liu,Jien-Wei, AU - Chung,Yu-Hsiu, AU - Su,Mao-Chang, AU - Lin,Meng-Chih, PY - 2007/6/9/pubmed PY - 2007/8/23/medline PY - 2007/6/9/entrez SP - 1148 EP - 52 JF - The American journal of tropical medicine and hygiene JO - Am J Trop Med Hyg VL - 76 IS - 6 N2 - Scrub typhus is a mite-borne infectious disease caused by Orientia tsutsugamushi. Acute respiratory distress syndrome (ARDS) is a serious complication of scrub typhus. This study retrospectively reviewed the medical records of 72 patients diagnosed with scrub typhus from January 1998 to August 2006 in Kaohsiung Chang Gung Memorial Hospital in Taiwan. Eight of 72 scrub typhus patients with ARDS were included in the study; the other patients without ARDS were used as controls. The mortality rate for the scrub typhus patients with ARDS was 25%. The eight patients seldom had underlying diseases. Initial presentations of dyspnea and cough, white blood cell count, hematocrit, total bilirubin, and delayed used of appropriate antibiotics use were significant predictors of ARDS. Multivariate analysis showed that albumin, prothrombin time, and delayed use of appropriate antibiotics were independent predictors of ARDS. Identification of these relative risk factors may help clinicians evaluate clinical cases of scrub typhus with ARDS. SN - 0002-9637 UR - https://www.unboundmedicine.com/medline/citation/17556627/Acute_respiratory_distress_syndrome_in_scrub_typhus_ L2 - http://www.diseaseinfosearch.org/result/210 DB - PRIME DP - Unbound Medicine ER -