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Effect of cinnamon on postprandial blood glucose, gastric emptying, and satiety in healthy subjects.
Am J Clin Nutr. 2007 Jun; 85(6):1552-6.AJ

Abstract

BACKGROUND

Previous studies of patients with type 2 diabetes showed that cinnamon lowers fasting serum glucose, triacylglycerol, and LDL- and total cholesterol concentrations.

OBJECTIVE

We aimed to study the effect of cinnamon on the rate of gastric emptying, the postprandial blood glucose response, and satiety in healthy subjects.

DESIGN

The gastric emptying rate (GER) was measured by using standardized real-time ultrasonography. Fourteen healthy subjects were assessed by using a crossover trial. The subjects were examined after an 8-h fast if they had normal fasting blood glucose concentrations. GER was calculated as the percentage change in the antral cross-sectional area 15-90 min after ingestion of 300 g rice pudding (GER1) or 300 g rice pudding and 6 g cinnamon (GER2).

RESULTS

The median value of GER1 was 37%, and that of GER2 was 34.5%. The addition of cinnamon to the rice pudding significantly delayed gastric emptying and lowered the postprandial glucose response (P < 0.05 for both). The reduction in the postprandial blood glucose concentration was much more noticeable and pronounced than was the lowering of the GER. The effect of cinnamon on satiety was not significant.

CONCLUSIONS

The intake of 6 g cinnamon with rice pudding reduces postprandial blood glucose and delays gastric emptying without affecting satiety. Inclusion of cinnamon in the diet lowers the postprandial glucose response, a change that is at least partially explained by a delayed GER.

Authors+Show Affiliations

Department of Medicine, Malmö University Hospital, University of Lund, Lund, Sweden. joanna.hlebowicz@skane.seNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17556692

Citation

Hlebowicz, Joanna, et al. "Effect of Cinnamon On Postprandial Blood Glucose, Gastric Emptying, and Satiety in Healthy Subjects." The American Journal of Clinical Nutrition, vol. 85, no. 6, 2007, pp. 1552-6.
Hlebowicz J, Darwiche G, Björgell O, et al. Effect of cinnamon on postprandial blood glucose, gastric emptying, and satiety in healthy subjects. Am J Clin Nutr. 2007;85(6):1552-6.
Hlebowicz, J., Darwiche, G., Björgell, O., & Almér, L. O. (2007). Effect of cinnamon on postprandial blood glucose, gastric emptying, and satiety in healthy subjects. The American Journal of Clinical Nutrition, 85(6), 1552-6.
Hlebowicz J, et al. Effect of Cinnamon On Postprandial Blood Glucose, Gastric Emptying, and Satiety in Healthy Subjects. Am J Clin Nutr. 2007;85(6):1552-6. PubMed PMID: 17556692.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of cinnamon on postprandial blood glucose, gastric emptying, and satiety in healthy subjects. AU - Hlebowicz,Joanna, AU - Darwiche,Gassan, AU - Björgell,Ola, AU - Almér,Lars-Olof, PY - 2007/6/9/pubmed PY - 2007/7/12/medline PY - 2007/6/9/entrez SP - 1552 EP - 6 JF - The American journal of clinical nutrition JO - Am J Clin Nutr VL - 85 IS - 6 N2 - BACKGROUND: Previous studies of patients with type 2 diabetes showed that cinnamon lowers fasting serum glucose, triacylglycerol, and LDL- and total cholesterol concentrations. OBJECTIVE: We aimed to study the effect of cinnamon on the rate of gastric emptying, the postprandial blood glucose response, and satiety in healthy subjects. DESIGN: The gastric emptying rate (GER) was measured by using standardized real-time ultrasonography. Fourteen healthy subjects were assessed by using a crossover trial. The subjects were examined after an 8-h fast if they had normal fasting blood glucose concentrations. GER was calculated as the percentage change in the antral cross-sectional area 15-90 min after ingestion of 300 g rice pudding (GER1) or 300 g rice pudding and 6 g cinnamon (GER2). RESULTS: The median value of GER1 was 37%, and that of GER2 was 34.5%. The addition of cinnamon to the rice pudding significantly delayed gastric emptying and lowered the postprandial glucose response (P < 0.05 for both). The reduction in the postprandial blood glucose concentration was much more noticeable and pronounced than was the lowering of the GER. The effect of cinnamon on satiety was not significant. CONCLUSIONS: The intake of 6 g cinnamon with rice pudding reduces postprandial blood glucose and delays gastric emptying without affecting satiety. Inclusion of cinnamon in the diet lowers the postprandial glucose response, a change that is at least partially explained by a delayed GER. SN - 0002-9165 UR - https://www.unboundmedicine.com/medline/citation/17556692/Effect_of_cinnamon_on_postprandial_blood_glucose_gastric_emptying_and_satiety_in_healthy_subjects_ DB - PRIME DP - Unbound Medicine ER -