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A green tea extract high in catechins reduces body fat and cardiovascular risks in humans.
Obesity (Silver Spring) 2007; 15(6):1473-83O

Abstract

OBJECTIVE

The body fat reducing effect and reduction of risks for cardiovascular disease by a green tea extract (GTE) high in catechins was investigated in humans with typical lifestyles.

RESEARCH METHODS AND PROCEDURES

Japanese women and men with visceral fat-type obesity were recruited for the trial. After a 2-week diet run-in period, a 12-week double-blind parallel multicenter trial was performed, in which the subjects ingested green tea containing 583 mg of catechins (catechin group) or 96 mg of catechins (control group) per day. Randomization was stratified by gender and body mass index at each medical institution. The subjects were instructed to maintain their usual dietary intake and normal physical activity.

RESULTS

Data were analyzed using per-protocol samples of 240 subjects (catechin group; n = 123, control group; n = 117). Decreases in body weight, body mass index, body fat ratio, body fat mass, waist circumference, hip circumference, visceral fat area, and subcutaneous fat area were found to be greater in the catechin group than in the control group. A greater decrease in systolic blood pressure (SBP) was found in the catechin group compared with the control group for subjects whose initial SBP was 130 mm Hg or higher. Low-density lipoprotein (LDL) cholesterol was also decreased to a greater extent in the catechin group. No adverse effect was found.

DISCUSSION

The continuous ingestion of a GTE high in catechins led to a reduction in body fat, SBP, and LDL cholesterol, suggesting that the ingestion of such an extract contributes to a decrease in obesity and cardiovascular disease risks.

Authors+Show Affiliations

Health Care Food Research Laboratories, Kao Corporation, 2-1-3, Bunka, Sumida-ku, Tokyo, 131-8501, Japan. nagao.tomonori@kao.co.jpNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Randomized Controlled Trial

Language

eng

PubMed ID

17557985

Citation

Nagao, Tomonori, et al. "A Green Tea Extract High in Catechins Reduces Body Fat and Cardiovascular Risks in Humans." Obesity (Silver Spring, Md.), vol. 15, no. 6, 2007, pp. 1473-83.
Nagao T, Hase T, Tokimitsu I. A green tea extract high in catechins reduces body fat and cardiovascular risks in humans. Obesity (Silver Spring). 2007;15(6):1473-83.
Nagao, T., Hase, T., & Tokimitsu, I. (2007). A green tea extract high in catechins reduces body fat and cardiovascular risks in humans. Obesity (Silver Spring, Md.), 15(6), pp. 1473-83.
Nagao T, Hase T, Tokimitsu I. A Green Tea Extract High in Catechins Reduces Body Fat and Cardiovascular Risks in Humans. Obesity (Silver Spring). 2007;15(6):1473-83. PubMed PMID: 17557985.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A green tea extract high in catechins reduces body fat and cardiovascular risks in humans. AU - Nagao,Tomonori, AU - Hase,Tadashi, AU - Tokimitsu,Ichiro, PY - 2007/6/15/pubmed PY - 2007/9/5/medline PY - 2007/6/15/entrez SP - 1473 EP - 83 JF - Obesity (Silver Spring, Md.) JO - Obesity (Silver Spring) VL - 15 IS - 6 N2 - OBJECTIVE: The body fat reducing effect and reduction of risks for cardiovascular disease by a green tea extract (GTE) high in catechins was investigated in humans with typical lifestyles. RESEARCH METHODS AND PROCEDURES: Japanese women and men with visceral fat-type obesity were recruited for the trial. After a 2-week diet run-in period, a 12-week double-blind parallel multicenter trial was performed, in which the subjects ingested green tea containing 583 mg of catechins (catechin group) or 96 mg of catechins (control group) per day. Randomization was stratified by gender and body mass index at each medical institution. The subjects were instructed to maintain their usual dietary intake and normal physical activity. RESULTS: Data were analyzed using per-protocol samples of 240 subjects (catechin group; n = 123, control group; n = 117). Decreases in body weight, body mass index, body fat ratio, body fat mass, waist circumference, hip circumference, visceral fat area, and subcutaneous fat area were found to be greater in the catechin group than in the control group. A greater decrease in systolic blood pressure (SBP) was found in the catechin group compared with the control group for subjects whose initial SBP was 130 mm Hg or higher. Low-density lipoprotein (LDL) cholesterol was also decreased to a greater extent in the catechin group. No adverse effect was found. DISCUSSION: The continuous ingestion of a GTE high in catechins led to a reduction in body fat, SBP, and LDL cholesterol, suggesting that the ingestion of such an extract contributes to a decrease in obesity and cardiovascular disease risks. SN - 1930-7381 UR - https://www.unboundmedicine.com/medline/citation/17557985/A_green_tea_extract_high_in_catechins_reduces_body_fat_and_cardiovascular_risks_in_humans_ L2 - https://doi.org/10.1038/oby.2007.176 DB - PRIME DP - Unbound Medicine ER -