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Emergence of KPC-2 and KPC-3 in carbapenem-resistant Klebsiella pneumoniae strains in an Israeli hospital.
Antimicrob Agents Chemother. 2007 Aug; 51(8):3026-9.AA

Abstract

Carbapenem resistance due to KPC has rarely been observed outside the United States. We noticed a sharp increase in carbapenem-resistant Klebsiella pneumoniae strains possessing KPC in Tel Aviv Medical Center from 2004 to 2006. Sixty percent of the isolates belonged to a single clone susceptible only to gentamicin and colistin and carried the bla(KPC-3) gene, while almost all other clones carried the bla(KPC-2) gene. This rapid dissemination of KPC outside the United States is worrisome.

Authors+Show Affiliations

Division of Epidemiology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17562800

Citation

Leavitt, Azita, et al. "Emergence of KPC-2 and KPC-3 in Carbapenem-resistant Klebsiella Pneumoniae Strains in an Israeli Hospital." Antimicrobial Agents and Chemotherapy, vol. 51, no. 8, 2007, pp. 3026-9.
Leavitt A, Navon-Venezia S, Chmelnitsky I, et al. Emergence of KPC-2 and KPC-3 in carbapenem-resistant Klebsiella pneumoniae strains in an Israeli hospital. Antimicrob Agents Chemother. 2007;51(8):3026-9.
Leavitt, A., Navon-Venezia, S., Chmelnitsky, I., Schwaber, M. J., & Carmeli, Y. (2007). Emergence of KPC-2 and KPC-3 in carbapenem-resistant Klebsiella pneumoniae strains in an Israeli hospital. Antimicrobial Agents and Chemotherapy, 51(8), 3026-9.
Leavitt A, et al. Emergence of KPC-2 and KPC-3 in Carbapenem-resistant Klebsiella Pneumoniae Strains in an Israeli Hospital. Antimicrob Agents Chemother. 2007;51(8):3026-9. PubMed PMID: 17562800.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Emergence of KPC-2 and KPC-3 in carbapenem-resistant Klebsiella pneumoniae strains in an Israeli hospital. AU - Leavitt,Azita, AU - Navon-Venezia,Shiri, AU - Chmelnitsky,Inna, AU - Schwaber,Mitchell J, AU - Carmeli,Yehuda, Y1 - 2007/06/11/ PY - 2007/6/15/pubmed PY - 2007/10/20/medline PY - 2007/6/15/entrez SP - 3026 EP - 9 JF - Antimicrobial agents and chemotherapy JO - Antimicrob Agents Chemother VL - 51 IS - 8 N2 - Carbapenem resistance due to KPC has rarely been observed outside the United States. We noticed a sharp increase in carbapenem-resistant Klebsiella pneumoniae strains possessing KPC in Tel Aviv Medical Center from 2004 to 2006. Sixty percent of the isolates belonged to a single clone susceptible only to gentamicin and colistin and carried the bla(KPC-3) gene, while almost all other clones carried the bla(KPC-2) gene. This rapid dissemination of KPC outside the United States is worrisome. SN - 0066-4804 UR - https://www.unboundmedicine.com/medline/citation/17562800/Emergence_of_KPC_2_and_KPC_3_in_carbapenem_resistant_Klebsiella_pneumoniae_strains_in_an_Israeli_hospital_ L2 - http://aac.asm.org/cgi/pmidlookup?view=long&pmid=17562800 DB - PRIME DP - Unbound Medicine ER -