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Colonic sensitive-motor alterations in the irritable bowel syndrome.
Ital J Gastroenterol. 1991 Nov; 23(8 Suppl 1):48-52.IJ

Abstract

The pathogenetic factors involved in the genesis of the irritable bowel syndrome (IBS) has not been fully explained yet. The abnormalities observed in these patients are a hypersensitivity to distension and an amplification of painful sensations. The motor activity of sigmoid colon shows an increased motility index in IBS patients with constipation and a low motility index in those with diarrhea. An hypercaloric meal induces a hypermotility in these patients. In our experience rectal distension evokes abdominal pain in 78% of cases at volumes of 100ml (less than than controls and constipated patients). The perfusion of rectum induces continuous abdominal pain in 89% of IBS patients. We can say that the motility of the whole colon over prolonged periods of time may represent an important progress in understanding the motor function in these patients.

Authors+Show Affiliations

Tomas-Ridocci M
Digestive Motility Unit, University Clinic Hospital, Valencia, Spain.
Moreno-Osset E
No affiliation info available
Minguez M
No affiliation info available
Ballester J
No affiliation info available
Mora F
No affiliation info available
Benages A
No affiliation info available

MeSH

Abdominal PainColonColon, SigmoidColonic Diseases, FunctionalGastrointestinal MotilityHumansRectumSensory ThresholdsTherapeutic Irrigation

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

1756283

Citation

Tomas-Ridocci, M, et al. "Colonic Sensitive-motor Alterations in the Irritable Bowel Syndrome." The Italian Journal of Gastroenterology, vol. 23, no. 8 Suppl 1, 1991, pp. 48-52.
Tomas-Ridocci M, Moreno-Osset E, Minguez M, et al. Colonic sensitive-motor alterations in the irritable bowel syndrome. Ital J Gastroenterol. 1991;23(8 Suppl 1):48-52.
Tomas-Ridocci, M., Moreno-Osset, E., Minguez, M., Ballester, J., Mora, F., & Benages, A. (1991). Colonic sensitive-motor alterations in the irritable bowel syndrome. The Italian Journal of Gastroenterology, 23(8 Suppl 1), 48-52.
Tomas-Ridocci M, et al. Colonic Sensitive-motor Alterations in the Irritable Bowel Syndrome. Ital J Gastroenterol. 1991;23(8 Suppl 1):48-52. PubMed PMID: 1756283.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Colonic sensitive-motor alterations in the irritable bowel syndrome. AU - Tomas-Ridocci,M, AU - Moreno-Osset,E, AU - Minguez,M, AU - Ballester,J, AU - Mora,F, AU - Benages,A, PY - 1991/11/1/pubmed PY - 1991/11/1/medline PY - 1991/11/1/entrez SP - 48 EP - 52 JF - The Italian journal of gastroenterology JO - Ital J Gastroenterol VL - 23 IS - 8 Suppl 1 N2 - The pathogenetic factors involved in the genesis of the irritable bowel syndrome (IBS) has not been fully explained yet. The abnormalities observed in these patients are a hypersensitivity to distension and an amplification of painful sensations. The motor activity of sigmoid colon shows an increased motility index in IBS patients with constipation and a low motility index in those with diarrhea. An hypercaloric meal induces a hypermotility in these patients. In our experience rectal distension evokes abdominal pain in 78% of cases at volumes of 100ml (less than than controls and constipated patients). The perfusion of rectum induces continuous abdominal pain in 89% of IBS patients. We can say that the motility of the whole colon over prolonged periods of time may represent an important progress in understanding the motor function in these patients. SN - 0392-0623 UR - https://www.unboundmedicine.com/medline/citation/1756283/Colonic_sensitive_motor_alterations_in_the_irritable_bowel_syndrome_ L2 - http://www.diseaseinfosearch.org/result/3876 DB - PRIME DP - Unbound Medicine ER -