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A comparison of the action of otilonium bromide and pinaverium bromide: study conducted under clinical control.
Ital J Gastroenterol 1991; 23(8 Suppl 1):64-6IJ

Abstract

We studied 40 patients with irritable bowel syndrome (IBS) which received in a simple-blind fashion otilonium and pinaverium bromide (15 days each drug). During each 15-day period we evaluated: number of pain episodes, intensity of pain, number of bowel movements, side effects. Otilonium bromide, (OB), compared with pinaverium bromide was able to significantly (p less than 0.05) reduce the number of pain attacks, whereas no significant differences were found between the 2 groups as regards the other parameters. The occurrence of side effects was similar in the two treatment courses. We can conclude that the two types of treatment were similarly useful in IBS, although OB seems more effective than pinaverium bromide.

Authors+Show Affiliations

Hepato-gastroenterology, University of Liège, Belgium.No affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

1756286

Citation

Defrance, P, and A Casini. "A Comparison of the Action of Otilonium Bromide and Pinaverium Bromide: Study Conducted Under Clinical Control." The Italian Journal of Gastroenterology, vol. 23, no. 8 Suppl 1, 1991, pp. 64-6.
Defrance P, Casini A. A comparison of the action of otilonium bromide and pinaverium bromide: study conducted under clinical control. Ital J Gastroenterol. 1991;23(8 Suppl 1):64-6.
Defrance, P., & Casini, A. (1991). A comparison of the action of otilonium bromide and pinaverium bromide: study conducted under clinical control. The Italian Journal of Gastroenterology, 23(8 Suppl 1), pp. 64-6.
Defrance P, Casini A. A Comparison of the Action of Otilonium Bromide and Pinaverium Bromide: Study Conducted Under Clinical Control. Ital J Gastroenterol. 1991;23(8 Suppl 1):64-6. PubMed PMID: 1756286.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A comparison of the action of otilonium bromide and pinaverium bromide: study conducted under clinical control. AU - Defrance,P, AU - Casini,A, PY - 1991/11/1/pubmed PY - 1991/11/1/medline PY - 1991/11/1/entrez SP - 64 EP - 6 JF - The Italian journal of gastroenterology JO - Ital J Gastroenterol VL - 23 IS - 8 Suppl 1 N2 - We studied 40 patients with irritable bowel syndrome (IBS) which received in a simple-blind fashion otilonium and pinaverium bromide (15 days each drug). During each 15-day period we evaluated: number of pain episodes, intensity of pain, number of bowel movements, side effects. Otilonium bromide, (OB), compared with pinaverium bromide was able to significantly (p less than 0.05) reduce the number of pain attacks, whereas no significant differences were found between the 2 groups as regards the other parameters. The occurrence of side effects was similar in the two treatment courses. We can conclude that the two types of treatment were similarly useful in IBS, although OB seems more effective than pinaverium bromide. SN - 0392-0623 UR - https://www.unboundmedicine.com/medline/citation/1756286/A_comparison_of_the_action_of_otilonium_bromide_and_pinaverium_bromide:_study_conducted_under_clinical_control_ L2 - https://medlineplus.gov/irritablebowelsyndrome.html DB - PRIME DP - Unbound Medicine ER -